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Quantum Machine Learning represents a paradigm shift at the intersection of Quantum Computing and Machine Learning, leveraging quantum phenomena such as superposition, entanglement, and quantum parallelism to address the limitations of…

Quantum Physics · Physics 2025-01-17 Sahil Tomar , Rajeshwar Tripathi , Sandeep Kumar

Free energy calculations are at the heart of physics-based analyses of biochemical processes. They allow us to quantify molecular recognition mechanisms, which determine a wide range of biological phenomena from how cells send and receive…

Training with huge datasets and a large number of participating devices leads to bottlenecks in federated learning (FL). Furthermore, the challenges of heterogeneity between multiple FL clients affect the overall performance of the system.…

Machine Learning · Computer Science 2025-06-06 Dev Gurung , Shiva Raj Pokhrel

Polymers are a versatile class of materials with widespread industrial applications. Advanced computational tools could revolutionize their design, but their complex, multi-scale nature poses significant modeling challenges. Conventional…

Ranking the binding of small molecules to protein receptors through physics-based computation remains challenging. Though inroads have been made using free energy methods, these fail when the underlying classical mechanical force fields are…

Chemical Physics · Physics 2020-04-21 Narbe Mardirossian , Yuhang Wang , David A. Pearlman , Garnet Kin-Lic Chan , Toru Shiozaki

Machine learning and quantum computing are two technologies that are causing a paradigm shift in the performance and behavior of certain algorithms, achieving previously unattainable results. Machine learning (kernel classification) has…

Quantum Physics · Physics 2020-04-28 Siddharth Sharma

Quantum machine learning (QML) has emerged as a promising domain to leverage the computational capabilities of quantum systems to solve complex classification tasks. In this work, we present the first comprehensive QML study by benchmarking…

Quantum Physics · Physics 2025-03-21 Gurinder Singh , Hongni Jin , Kenneth M. Merz

To address the computational challenges of ab initio molecular dynamics and the accuracy limitations of empirical force fields, the introduction of machine learning force fields has proven effective in various systems including metals and…

Soft Condensed Matter · Physics 2023-12-18 Junbao Hu , Liyang Zhou , Jian Jiang

In this work, we introduce CHIPS-FF (Computational High-Performance Infrastructure for Predictive Simulation-based Force Fields), a universal, open-source benchmarking platform for machine learning force fields (MLFFs). This platform…

Materials Science · Physics 2025-03-20 Daniel Wines , Kamal Choudhary

Accurately predicting enzyme functionality remains one of the major challenges in computational biology, particularly for enzymes with limited structural annotations or sequence homology. We present a novel multimodal Quantum Machine…

Machine Learning · Computer Science 2025-08-21 Murat Isik , Mandeep Kaur Saggi , Humaira Gowher , Sabre Kais

As quantum computers become increasingly practical, so does the prospect of using quantum computation to improve upon traditional algorithms. Kernel methods in machine learning is one area where such improvements could be realized in the…

Quantum Physics · Physics 2023-05-30 Ara Ghukasyan , Jack S. Baker , Oktay Goktas , Juan Carrasquilla , Santosh Kumar Radha

Bioelectrochemistry is crucial for understanding biological functions and driving applications in synthetic biology, healthcare, and catalysis. However, current simulation methods fail to capture both the stochastic nature of molecular…

Molecular spin qudits based on lanthanide complexes offer a promising platform for quantum technologies, combining chemical tunability with multi-level encoding. However, experimental demonstrations of their envisaged capabilities remain…

We introduce QMBench, a comprehensive benchmark designed to evaluate the capability of large language model agents in quantum materials research. This specialized benchmark assesses the model's ability to apply condensed matter physics…

The development of machine learning (ML) methods has made quantum chemistry (QC) calculations more accessible by reducing the compute cost incurred in conventional QC methods. This has since been translated into the overhead cost of…

Chemical Physics · Physics 2025-03-26 Vivin Vinod , Peter Zaspel

Quantum Federated Learning (QFL) is an emerging interdisciplinary field that merges the principles of Quantum Computing (QC) and Federated Learning (FL), with the goal of leveraging quantum technologies to enhance privacy, security, and…

Machine Learning · Computer Science 2024-08-20 Chao Ren , Rudai Yan , Huihui Zhu , Han Yu , Minrui Xu , Yuan Shen , Yan Xu , Ming Xiao , Zhao Yang Dong , Mikael Skoglund , Dusit Niyato , Leong Chuan Kwek

With the digitization of health data, the growth of electronic health and medical records lowers barriers for using algorithmic techniques for data analysis. While classical machine learning techniques for health data approach…

Quantum Physics · Physics 2025-05-09 Riddhi S. Gupta , Carolyn E. Wood , Teyl Engstrom , Jason D. Pole , Sally Shrapnel

We introduce the first large-scale dataset, MNISQ, for both the Quantum and the Classical Machine Learning community during the Noisy Intermediate-Scale Quantum era. MNISQ consists of 4,950,000 data points organized in 9 subdatasets.…

Recent progress in machine learning (ML) has made high-accuracy quantum chemistry (QC) calculations more accessible. Of particular interest are multifidelity machine learning (MFML) methods where training data from differing accuracies or…

Chemical Physics · Physics 2025-03-26 Vivin Vinod , Peter Zaspel

Quantum Monte Carlo (QMC) methods deliver highly accurate electronic structure calculations but are computationally intensive. The quantum Monte Carlo kernel library (QMCkl) provides a modular, portable collection of high-performance…