English
Related papers

Related papers: Cell State Transitions Beyond the Small-Noise Limi…

200 papers

In this paper, we study the phase transition behavior emerging from the interactions among multiple agents in the presence of noise. We propose a simple discrete-time model in which a group of non-mobile agents form either a fixed connected…

Optimization and Control · Mathematics 2008-10-21 Jialing Liu , Vikas Yadav , Hullas Sehgal , Joshua M. Olson , Haifeng Liu , Nicola Elia

An important characteristic of flocks of birds, school of fish, and many similar assemblies of self-propelled particles is the emergence of states of collective order in which the particles move in the same direction. When noise is added…

Statistical Mechanics · Physics 2015-01-19 M. Aldana , V. Dossetti , C. Huepe , V. M. Kenkre , H. Larralde

We consider a stochastic process with long-range dependence perturbed by multiplicative noise. The marginal distributions of both the original process and the noise have regularly-varying tails, with tail indices $\alpha,\alpha'>0$,…

Probability · Mathematics 2021-04-19 Olivier Durieu , Yizao Wang

Growth-fragmentation processes model systems of cells that grow continuously over time and then fragment into smaller pieces. Typically, on average, the number of cells in the system exhibits asynchronous exponential growth and, upon…

Probability · Mathematics 2023-06-08 Emma Horton , Alexander R. Watson

A description in terms of transition rates among cells is used to analyze self-diffusion of hard spheres in the fluid phase. Cell size is assumed much larger than the mean free path. Transition state theory is used to obtain an equation…

Statistical Mechanics · Physics 2021-11-15 Miguel Hoyuelos

Cell movement, for example during embryogenesis or tumor metastasis, is a complex dynamical process resulting from an intricate interplay of multiple components of the cellular migration machinery. At first sight, the paths of migrating…

Cell Behavior · Quantitative Biology 2009-04-17 Peter Dieterich , Rainer Klages , Roland Preuss , Albrecht Schwab

The effect of small-amplitude noise on excitable systems with large time-scale separation is analyzed. It is found that small random perturbations of the fast excitatory variable result in the onset of a quasi-deterministic limit cycle…

Quantitative Methods · Quantitative Biology 2007-05-23 Cyrill B. Muratov , Eric Vanden-Eijnden , Weinan E

Measurement in biological systems became a subject of concern as a consequence of numerous reports on limited reproducibility of experimental results. To reveal origins of this inconsistency, we have examined general features of biological…

Other Quantitative Biology · Quantitative Biology 2017-04-03 Dalibor Štys , Jan Urban , Renata Rychtáriková , Anna Zhyrova , Petr Císař

The circuit complexity of time-evolved pure quantum states grows linearly in time for an exponentially long time. This behavior has been proven in certain models, is conjectured to hold for generic quantum many-body systems, and is believed…

High Energy Physics - Theory · Physics 2025-10-22 Yale Fan , Nicholas Hunter-Jones , Andreas Karch , Shivan Mittal

Stochastic transitions between discrete microscopic states play an important role in many physical and biological systems. Often, these transitions lead to fluctuations on a macroscopic scale. A classic example from neuroscience is the…

Statistical Mechanics · Physics 2024-02-20 Lukas Ramlow , Benjamin Lindner

While Kramers' rates have been studied for almost a century, the transition path time between states has only recently received attention. Transition paths between different energy levels are expected to be indistinguishable in shape and…

Statistical Mechanics · Physics 2020-06-02 Jannes Gladrow , Marco Ribezzi-Crivellari , Felix Ritort , Ulrich F. Keyser

Motivated by recent findings, we discuss the existence of a direct and robust mechanism providing discontinuous absorbing transitions in short range systems with single species, with no extra symmetries or conservation laws. We consider…

Statistical Mechanics · Physics 2014-02-10 Carlos E. Fiore

The number of defects which are generated on crossing a quantum phase transition can be minimized by choosing properly designed time-dependent pulses. In this work we determine what are the ultimate limits of this optimization. We discuss…

Other Condensed Matter · Physics 2015-05-20 T. Caneva , T. Calarco , R. Fazio , G. E. Santoro , S. Montangero

Cells are known to utilize biochemical noise to probabilistically switch between distinct gene expression states. We demonstrate that such noise-driven switching is dominated by tails of probability distributions and is therefore…

Molecular Networks · Quantitative Biology 2009-11-13 Pankaj Mehta , Ranjan Mukhopadhyay , Ned S. Wingreen

It has been recently shown that the exponential growth rate of a population of bacterial cells starting from a single cell shows transient oscillations due to early synchronized bursts of division. These oscillations are enhanced by cell…

Populations and Evolution · Quantitative Biology 2024-08-05 Yaïr Hein , Farshid Jafarpour

Do biological cells sense time by the number of their divisions, a process that ends at senescence? We consider the question "can the cell's perception of time be expressed through the length of the shortest telomere?" The answer is that…

Subcellular Processes · Quantitative Biology 2017-11-15 Zeev Schuss , Kimsy Tor , David Holcman

Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

A granular system confined in a quasi two-dimensional box that is vertically vibrated can transit to an absorbing state in which all particles bounce vertically in phase with the box, with no horizontal motion. In principle, this state can…

Statistical Mechanics · Physics 2015-06-18 Baptiste Néel , Ignacio Rondini , Alex Turzillo , Nicolás Mujica , Rodrigo Soto

We explore reachable sets of open $n$-qubit quantum systems, the coherent parts of which are under full unitary control and that have just one qubit whose Markovian noise amplitude can be modulated in time such as to provide an additional…

Quantum Physics · Physics 2015-03-20 V. Bergholm , T. Schulte-Herbrueggen

Many driven systems alternate between bursts of activity and quiescence and can become trapped in an absorbing state, such as complete inactivity in reaction-diffusion processes or extinction in predator-prey dynamics. It is generally…

Statistical Mechanics · Physics 2026-05-14 Kartik Chhajed , P. K. Mohanty