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Pandemic(epidemic) modeling, aiming at disease spreading analysis, has always been a popular research topic especially following the outbreak of COVID-19 in 2019. Some representative models including SIR-based deep learning prediction…

Machine Learning · Computer Science 2022-12-07 Danfeng Guo , Zijie Huang , Junheng Hao , Yizhou Sun , Wei Wang , Demetri Terzopoulos

When investigating epidemic dynamics through differential models, the parameters needed to understand the phenomenon and to simulate forecast scenarios require a delicate calibration phase, often made even more challenging by the scarcity…

Numerical Analysis · Mathematics 2023-09-11 Giulia Bertaglia , Chuan Lu , Lorenzo Pareschi , Xueyu Zhu

In this work, we present an approach called Disease Informed Neural Networks (DINNs) that can be employed to effectively predict the spread of infectious diseases. This approach builds on a successful physics informed neural network…

Machine Learning · Computer Science 2022-08-26 Sagi Shaier , Maziar Raissi , Padmanabhan Seshaiyer

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

The COVID-19 pandemic highlighted the need to improve the modeling, estimation, and prediction of how infectious diseases spread. SEIR-like models have been particularly successful in providing accurate short-term predictions. This study…

Populations and Evolution · Quantitative Biology 2024-12-31 Jorge P. Zubelli , Jennifer Loria , Vinicius V. L. Albani

Mathematical models of infectious diseases exhibit robust dynamics such as stable endemic or a disease-free equilibrium, or convergence of the solutions to periodic epidemic waves. The present work shows that the accuracy of such dynamics…

Applications · Statistics 2022-05-04 Hadeel AlQadi , Majid Bani-Yaghoub

In this paper, we propose a machine learning technics and SIR models (deterministic and stochastic cases) with numerical approximations to predict the number of cases infected with the COVID-19, for both in few days and the following three…

Populations and Evolution · Quantitative Biology 2020-04-29 Babacar Mbaye Ndiaye , Lena Tendeng , Diaraf Seck

The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

Populations and Evolution · Quantitative Biology 2020-06-11 Kok Yew Ng , Meei Mei Gui

Physics-Informed Neural Networks (PINNs) have recently emerged as a novel approach to simulate complex physical systems on the basis of both data observations and physical models. In this work, we investigate the use of PINNs for various…

Analysis of PDEs · Mathematics 2024-03-27 Guillaume Coulaud , Maxime Le , Régis Duvigneau

The importance and cost of time-domain simulations when studying power systems have exponentially increased in the last decades. With the growing share of renewable energy sources, the slow and predictable responses from large turbines are…

Systems and Control · Electrical Eng. & Systems 2025-10-08 Ignasi Ventura Nadal , Rahul Nellikkath , Spyros Chatzivasileiadis

We develop a physics-informed neural network (PINN) framework for parameter estimation in fractional-order SEIRD epidemic models. By embedding the Caputo fractional derivative into the network residuals via the L1 discretization scheme, our…

Machine Learning · Statistics 2025-09-30 Achraf Zinihi

Physics-informed neural networks (PINNs) have great potential for flexibility and effectiveness in forward modeling and inversion of seismic waves. However, coordinate-based neural networks (NNs) commonly suffer from the "spectral bias"…

Geophysics · Physics 2025-06-19 Yi Ding , Su Chen , Hiroe Miyake , Xiaojun Li

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

This paper introduces a novel approach to solve inverse problems by leveraging deep learning techniques. The objective is to infer unknown parameters that govern a physical system based on observed data. We focus on scenarios where the…

Machine Learning · Computer Science 2023-10-02 Sidney Besnard , Frédéric Jurie , Jalal M. Fadili

Highly-interconnected societies difficult to model the spread of infectious diseases such as COVID-19. Single-region SIR models fail to account for incoming forces of infection and expanding them to a large number of interacting regions…

Machine Learning · Computer Science 2023-11-06 Adrian Rojas-Campos , Lukas Stelz , Pascal Nieters

The SARS-CoV-2 infectious outbreak has rapidly spread across the globe and precipitated varying policies to effectuate physical distancing to ameliorate its impact. In this study, we propose a new hybrid machine learning model, SIRNet, for…

Populations and Evolution · Quantitative Biology 2020-04-23 Nicholas Soures , David Chambers , Zachariah Carmichael , Anurag Daram , Dimpy P. Shah , Kal Clark , Lloyd Potter , Dhireesha Kudithipudi

Physics-informed neural networks (PINNs) provide a powerful framework for learning governing equations of dynamical systems from data. Biologically-informed neural networks (BINNs) are a variant of PINNs that preserve the known differential…

Machine Learning · Computer Science 2026-04-21 William Lavery , Jodie A. Cochrane , Christian Olesen , Dagim S. Tadele , John T. Nardini , Sara Hamis

The unprecedented coronavirus disease 2019 (COVID-19) pandemic is still a worldwide threat to human life since its invasion into the daily lives of the public in the first several months of 2020. Predicting the size of confirmed cases is…

Applications · Statistics 2020-12-02 Xinyu Wang , Lu Yang , Hong Zhang , Zhouwang Yang , Catherine Liu

We present a new efficient hybrid parameter estimation method based on the idea, that if nonlinear dynamic models are stated in terms of a system of equations that is linear in terms of the parameters, then regularized ordinary least…

In the field of pharmacokinetics and pharmacodynamics (PKPD) modeling, which plays a pivotal role in the drug development process, traditional models frequently encounter difficulties in fully encapsulating the complexities of drug…

Quantitative Methods · Quantitative Biology 2024-09-23 Nazanin Ahmadi Daryakenari , Shupeng Wang , George Karniadakis