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Multi-step retrieval-augmented generation (RAG) has become a widely adopted strategy for enhancing large language models (LLMs) on tasks that demand global comprehension and intensive reasoning. Although many RAG systems incorporate a…

Computation and Language · Computer Science 2026-05-28 Chulun Zhou , Chunkang Zhang , Guoxin Yu , Fandong Meng , Jie Zhou , Wai Lam , Mo Yu

Multimodal reasoning with large language models (LLMs) often suffers from hallucinations and the presence of deficient or outdated knowledge within LLMs. Some approaches have sought to mitigate these issues by employing textual knowledge…

Computation and Language · Computer Science 2024-06-06 Junlin Lee , Yequan Wang , Jing Li , Min Zhang

Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

Despite remarkable progress made in natural language processing, even the state-of-the-art models often make incorrect predictions. Such predictions hamper the reliability of systems and limit their widespread adoption in real-world…

Computation and Language · Computer Science 2023-05-04 Neeraj Varshney , Chitta Baral

Motivated by the challenge to improve the adversarial robustness, security, and trust of medical decision making intelligent agents, this study develops a full-link security enhancement framework, which describes "input risk perception -…

Cryptography and Security · Computer Science 2026-05-12 Saisai Hu

Conversational diagnosis requires multi-turn history-taking, where an agent asks clarifying questions to refine differential diagnoses under incomplete information. Existing approaches often rely on the parametric knowledge of a model or…

Artificial Intelligence · Computer Science 2026-02-04 Jeongmoon Won , Seungwon Kook , Yohan Jo

Multi-Turn Long-Form Question Answering (MT-LFQA) is a key application paradigm of Large Language Models (LLMs) in knowledge-intensive domains. However, existing benchmarks are limited to single-turn dialogue, while multi-turn dialogue…

Computation and Language · Computer Science 2025-09-29 Junhao Chen , Yu Huang , Siyuan Li , Rui Yao , Hanqian Li , Hanyu Zhang , Jungang Li , Jian Chen , Bowen Wang , Xuming Hu

In this paper, we investigate the retrieval-augmented generation (RAG) based on Knowledge Graphs (KGs) to improve the accuracy and reliability of Large Language Models (LLMs). Recent approaches suffer from insufficient and repetitive…

Computation and Language · Computer Science 2024-04-22 Xinke Jiang , Ruizhe Zhang , Yongxin Xu , Rihong Qiu , Yue Fang , Zhiyuan Wang , Jinyi Tang , Hongxin Ding , Xu Chu , Junfeng Zhao , Yasha Wang

LLMs cannot reliably recognize their parametric knowledge boundaries and often hallucinate answers to outside-of-boundary questions. In this paper, we introduce MASH (Modeling Abstention via Selective Help-seeking), a training framework…

Computation and Language · Computer Science 2026-04-14 Mustafa Omer Gul , Claire Cardie , Tanya Goyal

Robust model-editing techniques are essential for deploying large language models (LLMs) in practical applications, as they enable cost-effective ways to deal with challenges such as privacy breaches, bias mitigation and misinformation…

Machine Learning · Computer Science 2026-01-19 Manit Baser , Dinil Mon Divakaran , Mohan Gurusamy

Retrieval-Augmented Generation (RAG) integrates external knowledge to enhance Large Language Models (LLMs), yet systems remain susceptible to two critical flaws: providing correct answers without explicit grounded evidence and producing…

Computation and Language · Computer Science 2026-01-09 Yibo Zhao , Jiapeng Zhu , Zichen Ding , Xiang Li

Trustworthy biomedical question answering (QA) systems must not only provide accurate answers but also justify them with current, verifiable evidence. Retrieval-augmented approaches partially address this gap but lack mechanisms to…

Computation and Language · Computer Science 2026-03-31 Yiqing Zhang , Xiaozhong Liu , Fabricio Murai

Large language models (LLMs), such as GPT3.5, GPT4 and LLAMA2 perform surprisingly well and outperform human experts on many tasks. However, in many domain-specific evaluations, these LLMs often suffer from hallucination problems due to…

Computation and Language · Computer Science 2024-04-19 Yuqi Wang , Boran Jiang , Yi Luo , Dawei He , Peng Cheng , Liangcai Gao

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

Large language models (LLMs) define a distribution over text, which can be viewed as a probabilistic representation of uncertainty: sampling K responses yields a belief state - responses a model deems plausible. Existing work exploits this…

Computation and Language · Computer Science 2026-05-26 Joris Baan , Wilker Aziz , Barbara Plank , Raquel Fernández

Medical large language model (LLM) evaluations rely on simplified, exam-style benchmarks that rarely reflect the ambiguity of real-world medical inquiries. We introduce the CLinical Evaluation of Ambiguity and Reliability (CLEAR) framework,…

Computation and Language · Computer Science 2026-05-12 Kevin H. Guo , Chao Yan , Avinash Baidya , Katherine Brown , Xiang Gao , Juming Xiong , Zhijun Yin , Bradley A. Malin

Reasoning benchmarks measure clinical performance on clean inputs. We evaluate the step before reasoning: retrieval over real EHR notes, where negation, temporality, and family-versus-patient attribution can flip a correct answer to a wrong…

Computation and Language · Computer Science 2026-05-13 Alex Stinard

Multimodal document question answering requires retrieving dispersed evidence from visually rich long documents and performing reliable reasoning over heterogeneous information. Existing multimodal RAG systems remain limited by two…

Information Retrieval · Computer Science 2026-03-18 Jiashu Yang , Chi Zhang , Abudukelimu Wuerkaixi , Xuxin Cheng , Cao Liu , Ke Zeng , Xu Jia , Xunliang Cai

This study presents a systematic approach to identifying and characterizing student misconceptions in online learning environments through a novel combination of quantitative performance analysis and large language model (LLM) assessment.…

Computation and Language · Computer Science 2026-05-04 Michael J. Parker , Maria G. Zavala-Cerna