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We propose a difference-in-differences (DiD) framework with mediation for possibly multivalued discrete or continuous treatments and mediators, aimed at identifying the direct effect of the treatment on the outcome (net of effects operating…

Econometrics · Economics 2026-03-02 Martin Huber , Sarina Joy Oberhänsli

Estimation of heterogeneous treatment effects (HTE) is of prime importance in many disciplines, ranging from personalized medicine to economics among many others. Random forests have been shown to be a flexible and powerful approach to HTE…

Methodology · Statistics 2025-10-07 Susanne Dandl , Torsten Hothorn , Heidi Seibold , Erik Sverdrup , Stefan Wager , Achim Zeileis

Multi-modal methods establish comprehensive superiority over uni-modal methods. However, the imbalanced contributions of different modalities to task-dependent predictions constantly degrade the discriminative performance of canonical…

Machine Learning · Computer Science 2025-04-18 Yi Li , Fei Song , Changwen Zheng , Jiangmeng Li , Fuchun Sun , Hui Xiong

Conventional multi-hop fact verification models are prone to rely on spurious correlations from the annotation artifacts, leading to an obvious performance decline on unbiased datasets. Among the various debiasing works, the causal…

Computation and Language · Computer Science 2024-03-06 Congzhi Zhang , Linhai Zhang , Deyu Zhou

The causal effect of a treatment can vary from person to person based on their individual characteristics and predispositions. Mining for patterns of individual-level effect differences, a problem known as heterogeneous treatment effect…

Machine Learning · Computer Science 2019-09-04 Christopher Tran , Elena Zheleva

Decision-making across various fields, such as medicine, heavily relies on conditional average treatment effects (CATEs). Practitioners commonly make decisions by checking whether the estimated CATE is positive, even though the…

Machine Learning · Computer Science 2025-05-23 Dennis Frauen , Valentyn Melnychuk , Jonas Schweisthal , Mihaela van der Schaar , Stefan Feuerriegel

Heterogeneous treatment effects (HTEs) are increasingly estimated using machine learning models that produce highly personalized predictions of treatment effects. In practice, however, predicted treatment effects are rarely interpreted,…

Federated learning (FL) facilitates edge devices to cooperatively train a global shared model while maintaining the training data locally and privately. However, a common assumption in FL requires the participating edge devices to have…

Machine Learning · Computer Science 2024-02-02 Yun-Hin Chan , Zhihan Jiang , Jing Deng , Edith C. -H. Ngai

Federated learning offers a paradigm to the challenge of preserving privacy in distributed machine learning. However, datasets distributed across each client in the real world are inevitably heterogeneous, and if the datasets can be…

Machine Learning · Computer Science 2024-09-19 Xiuhua Lu , Peng Li , Xuefeng Jiang

In a federated learning (FL) system, decentralized data owners (clients) could upload their locally trained models to a central server, to jointly train a global model. Malicious clients may plant backdoors into the global model through…

Cryptography and Security · Computer Science 2024-06-03 Songze Li , Yanbo Dai

When treating depression, clinicians are interested in determining the optimal treatment for a given patient, which is challenging given the amount of treatments available. To advance individualized treatment allocation, integrating data…

Analyses of heterogeneous treatment effects (HTE) are common in applied causal inference research. However, when outcomes are latent variables assessed via psychometric instruments such as educational tests, standard methods ignore the…

The front-door criterion is an identification strategy for the intervention-specific mean outcome in settings where the standard back-door criterion fails due to unmeasured exposure-outcome confounders, but an intermediate variable exists…

Methodology · Statistics 2026-03-17 Marie S. Breum , Helene C. W. Rytgaard , Torben Martinussen , Erin E. Gabriel

The treatment effects of medications play a key role in guiding medical prescriptions. They are usually assessed with randomized controlled trials (RCTs), which are expensive. Recently, large-scale electronic health records (EHRs) have…

Machine Learning · Statistics 2019-08-20 Linying Zhang , Yixin Wang , Anna Ostropolets , Jami J. Mulgrave , David M. Blei , George Hripcsak

We consider identification and inference for the average treatment effect and heterogeneous treatment effect conditional on observable covariates in the presence of unmeasured confounding. Since point identification of these treatment…

Methodology · Statistics 2025-03-04 Kan Chen , Jeffrey Zhang , Bingkai Wang , Dylan S. Small

This paper introduces a scalable causal inference framework for estimating the immediate, session-level effects of on-demand human tutoring embedded within adaptive learning systems. Because students seek assistance at moments of…

Human-Computer Interaction · Computer Science 2026-02-24 Kirk Vanacore , Danielle R Thomas , Digory Smith , Bibi Groot , Justin Reich , Rene Kizilcec

In many scenarios such as genome-wide association studies where dependences between variables commonly exist, it is often of interest to infer the interaction effects in the model. However, testing pairwise interactions among millions of…

Methodology · Statistics 2022-09-02 Jingyi Duan , Yang Ning , Xi Chen , Yong Chen

It is valuable for any decision maker to know the impact of decisions (treatments) on average and for subgroups. The causal machine learning literature has recently provided tools for estimating group average treatment effects (GATE) to…

Econometrics · Economics 2025-01-10 Nora Bearth , Michael Lechner

Federated learning (FL) is a distributed collaborative learning method, where multiple clients learn together by sharing gradient updates instead of raw data. However, it is well-known that FL is vulnerable to manipulated updates from…

Machine Learning · Computer Science 2025-03-06 Dimitar Chakarov , Nikita Tsoy , Kristian Minchev , Nikola Konstantinov

End-to-End autonomous driving (E2E-AD) systems face challenges in lifelong learning, including catastrophic forgetting, difficulty in knowledge transfer across diverse scenarios, and spurious correlations between unobservable confounders…

Machine Learning · Computer Science 2026-03-31 Jiayuan Du , Yuebing Song , Yiming Zhao , Xianghui Pan , Jiawei Lian , Yuchu Lu , Liuyi Wang , Chengju Liu , Qijun Chen