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In Fall 2020, several European countries reported rapid increases in COVID-19 cases along with growing estimates of the effective reproduction rates. Such an acceleration in epidemic spread is usually attributed to time-dependent effects,…

Populations and Evolution · Quantitative Biology 2022-11-30 Nazmi Burak Budanur , Björn Hof

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on…

Classic results establish that encouraging predictive diversity improves performance in ensembles of low-capacity models, e.g. through bagging or boosting. Here we demonstrate that these intuitions do not apply to high-capacity neural…

Machine Learning · Computer Science 2024-01-11 Taiga Abe , E. Kelly Buchanan , Geoff Pleiss , John P. Cunningham

Loss reserving generally focuses on identifying a single model that can generate superior predictive performance. However, different loss reserving models specialise in capturing different aspects of loss data. This is recognised in…

Methodology · Statistics 2024-06-04 Benjamin Avanzi , Yanfeng Li , Bernard Wong , Alan Xian

The COVID-19 pandemic and its multiple outbreaks have challenged governments around the world. Much of the epidemiological modeling was based on pre-pandemic contact information of the population, which changed drastically due to…

Populations and Evolution · Quantitative Biology 2023-09-15 Santiago Rosa , Manuel Pulido , Juan Ruiz , Tadeo Cocucci

When making predictions about ecosystems, we often have available a number of different ecosystem models that attempt to represent their dynamics in a detailed mechanistic way. Each of these can be used as simulators of large-scale…

The predictive advantage of combining several different predictive models is widely accepted. Particularly in time series forecasting problems, this combination is often dynamic to cope with potential non-stationary sources of variation…

Machine Learning · Statistics 2021-04-06 Vitor Cerqueira , Luis Torgo , Carlos Soares , Albert Bifet

Compartmental models are widely adopted to describe and predict the spreading of infectious diseases. The unknown parameters of such models need to be estimated from the data. Furthermore, when some of the model variables are not…

Physics and Society · Physics 2021-01-18 Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

Across the world, scholars are racing to predict the spread of the novel coronavirus, COVID-19. Such predictions are often pursued by numerically simulating epidemics with a large number of plausible combinations of relevant parameters. It…

Physics and Society · Physics 2021-02-03 Jonas L. Juul , Kaare Græsbøll , Lasse Engbo Christiansen , Sune Lehmann

Deep learning classifiers are assisting humans in making decisions and hence the user's trust in these models is of paramount importance. Trust is often a function of constant behavior. From an AI model perspective it means given the same…

Mathematical models are increasing adopted for setting targets for disease prevention and control. As model-informed policies are implemented, however, the inaccuracies of some forecasts become apparent, for example overprediction of…

Real-time forecasting of disease outbreaks requires standardized outputs generated in a timely manner. Development of pipelines to automate infectious disease forecasts can ensure that parameterization and software dependencies are common…

Other Quantitative Biology · Quantitative Biology 2022-08-11 VP Nagraj , Chris Hulme-Lowe , Shakeel Jessa , Stephen D. Turner

The increasing adoption of data-driven decision-making in public health has established epidemic forecasting as a critical area of research. Recent advances in multivariate forecasting models better capture complex temporal dependencies…

Machine Learning · Computer Science 2026-05-13 Madhurima Panja , Danny D'Agostino , Huitao Li , Tanujit Chakraborty , Nan Liu

Mesoscale forecasts are now routinely performed as elements of operational forecasts and their outputs do appear convincing. However, despite their realistic appearance at times the comparison to observations is less favorable. At the grid…

Atmospheric and Oceanic Physics · Physics 2016-10-26 Markus Gross

This report summarizes the discussions and conclusions of a 2-day multidisciplinary workshop that brought together researchers and practitioners in healthcare, computer science, and social sciences to explore what lessons were learned and…

Computers and Society · Computer Science 2024-03-04 David Danks , Rada Mihalcea , Katie Siek , Mona Singh , Brian Dixon , Haley Griffin

In machine learning ensembles predictions from multiple models are aggregated. Despite widespread use and strong performance of ensembles in applied problems little is known about the mathematical properties of aggregating models and…

Machine Learning · Computer Science 2024-08-27 Jeremy Kedziora

We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control…

Systems and Control · Electrical Eng. & Systems 2022-11-21 Tamas G. Molnar , Andrew W. Singletary , Gabor Orosz , Aaron D. Ames

An ensemble of classifiers combines several single classifiers to deliver a final prediction or classification decision. An increasingly provoking question is whether such systems can outperform the single best classifier. If so, what form…

Machine Learning · Computer Science 2022-09-07 Bhekisipho Twala , Eamon Molloy

This work proposes a unified framework for portfolio allocation, covering both asset selection and optimization, based on a multiple-hypothesis predict-then-optimize approach. The portfolio is modeled as a structured ensemble, where each…

Portfolio Management · Quantitative Finance 2025-11-19 Alejandro Rodriguez Dominguez , Muhammad Shahzad , Xia Hong