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Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

Applications · Statistics 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

Ensemble forecasts often outperform forecasts from individual standalone models, and have been used to support decision-making and policy planning in various fields. As collaborative forecasting efforts to create effective ensembles grow,…

Methodology · Statistics 2026-01-12 Minsu Kim , Evan L. Ray , Nicholas G. Reich

The U.S. COVID-19 Forecast Hub aggregates forecasts of the short-term burden of COVID-19 in the United States from many contributing teams. We study methods for building an ensemble that combines forecasts from these teams. These…

Forecasts of hospitalisations of infectious diseases play an important role for allocating healthcare resources during epidemics and pandemics. Large-scale analysis of model forecasts during the COVID-19 pandemic has shown that the model…

Populations and Evolution · Quantitative Biology 2025-05-20 Grégoire Béchade , Torbjörn Lundh , Philip Gerlee

Model multiplicity refers to the existence of multiple machine learning models that describe the data equally well but may produce different predictions on individual samples. In medicine, these models can admit conflicting predictions for…

Forecasting new cases, hospitalizations, and disease-induced deaths is an important part of infectious disease surveillance and helps guide health officials in implementing effective countermeasures. For disease surveillance in the U.S.,…

Physics and Society · Physics 2022-06-22 Nino Antulov-Fantulin , Lucas Böttcher

Accurate and reliable predictions of infectious disease dynamics can be valuable to public health organizations that plan interventions to decrease or prevent disease transmission. A great variety of models have been developed for this…

Machine Learning · Statistics 2018-07-04 Evan L. Ray , Nicholas G. Reich

Ensembles depend on diversity for improved performance. Many ensemble training methods, therefore, attempt to optimize for diversity, which they almost always define in terms of differences in training set predictions. In this paper,…

Machine Learning · Computer Science 2020-02-10 Andrew Slavin Ross , Weiwei Pan , Leo Anthony Celi , Finale Doshi-Velez

Seasonal influenza infects between 10 and 50 million people in the United States every year, overburdening hospitals during weeks of peak incidence. Named by the CDC as an important tool to fight the damaging effects of these epidemics,…

Applications · Statistics 2020-05-19 Thomas McAndrew , Nicholas G. Reich

It is increasingly common to encounter prediction tasks in the biomedical sciences for which multiple datasets are available for model training. Common approaches such as pooling datasets and applying standard statistical learning methods…

Machine Learning · Statistics 2021-10-05 Gabriel Loewinger , Rolando Acosta Nunez , Rahul Mazumder , Giovanni Parmigiani

Given the continuous increase in dataset sizes and the complexity of forecasting models, the trade-off between forecast accuracy and computational cost is emerging as an extremely relevant topic, especially in the context of ensemble…

Machine Learning · Computer Science 2025-07-10 Marco Zanotti

The COVID-19 pandemic has placed forecasting models at the forefront of health policy making. Predictions of mortality and hospitalization help governments meet planning and resource allocation challenges. In this paper, we consider the…

Applications · Statistics 2020-08-21 Kathryn S. Taylor , James W. Taylor

The COVID-19 pandemic has brought forth the importance of epidemic forecasting for decision makers in multiple domains, ranging from public health to the economy as a whole. While forecasting epidemic progression is frequently…

Machine Learning · Computer Science 2022-07-21 Alexander Rodríguez , Harshavardhan Kamarthi , Pulak Agarwal , Javen Ho , Mira Patel , Suchet Sapre , B. Aditya Prakash

Recent work has shown that models trained to the same objective, and which achieve similar measures of accuracy on consistent test data, may nonetheless behave very differently on individual predictions. This inconsistency is undesirable in…

Machine Learning · Computer Science 2021-11-17 Emily Black , Klas Leino , Matt Fredrikson

This work addresses the challenge of providing consistent explanations for predictive models in the presence of model indeterminacy, which arises due to the existence of multiple (nearly) equally well-performing models for a given dataset…

Machine Learning · Computer Science 2023-06-14 Dan Ley , Leonard Tang , Matthew Nazari , Hongjin Lin , Suraj Srinivas , Himabindu Lakkaraju

Ensembles, which employ a set of classifiers to enhance classification accuracy collectively, are crucial in the era of big data. However, although there is general agreement that the relation between ensemble size and its prediction…

Machine Learning · Computer Science 2023-08-29 Enes Bektas , Fazli Can

Ensembling is a simple and popular technique for boosting evaluation performance by training multiple models (e.g., with different initializations) and aggregating their predictions. This approach is commonly reserved for the largest…

Machine Learning · Computer Science 2020-05-05 Dan Kondratyuk , Mingxing Tan , Matthew Brown , Boqing Gong

Ensemble models often achieve higher accuracy than single learners, but their ability to maintain small generalization gaps is not always well understood. This study examines how ensembles balance accuracy and overfitting across four…

Machine Learning · Computer Science 2025-12-08 Zubair Ahmed Mohammad

Background: Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic, comparative…

Ensemble forecasting is, so far, the most successful approach to produce relevant forecasts with an estimation of their uncertainty. The main limitations of ensemble forecasting are the high computational cost and the difficulty to capture…

Machine Learning · Computer Science 2022-12-21 Maximiliano A. Sacco , Juan J. Ruiz , Manuel Pulido , Pierre Tandeo
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