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Optimizing black-box functions is a fundamental problem in science and engineering. To solve this problem, many approaches learn a surrogate function that estimates the underlying objective from limited historical evaluations. Large…

Machine Learning · Computer Science 2025-10-23 Tung Nguyen , Aditya Grover

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Large language models (LLMs) have recently shown strong reasoning capabilities beyond traditional language tasks, motivating their use for numerical optimization. This paper presents LLMize, an open-source Python framework that enables…

Machine Learning · Computer Science 2026-01-06 M. Rizki Oktavian

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Large Language Models (LLMs) have demonstrated remarkable reasoning abilities, prompting interest in their application as black-box optimizers. This paper asserts that LLMs possess the capability for zero-shot optimization across diverse…

The vocabulary used by language models (LM) - defined by the tokenizer - plays a key role in text generation quality. However, its impact remains under-explored in radiology. In this work, we address this gap by systematically comparing…

Computation and Language · Computer Science 2025-08-14 Hermione Warr , Wentian Xu , Harry Anthony , Yasin Ibrahim , Daniel McGowan , Konstantinos Kamnitsas

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

The rapid development of large language models (LLMs) has transformed many industries, including healthcare. However, previous medical LLMs have largely focused on leveraging general medical knowledge to provide responses, without…

Computation and Language · Computer Science 2024-12-23 Ruize Shi , Hong Huang , Wei Zhou , Kehan Yin , Kai Zhao , Yun Zhao

Future wireless networks are expected to incorporate diverse services that often lack general mathematical models. To address such black-box network management tasks, the large language model (LLM) optimizer framework, which leverages…

Information Theory · Computer Science 2025-07-04 Hoon Lee , Wentao Zhou , Merouane Debbah , Inkyu Lee

Large Language Models (LLMs) have already been widely adopted for automated algorithm design, demonstrating strong abilities in generating and evolving algorithms across various fields. Existing work has largely focused on examining their…

Machine Learning · Computer Science 2026-03-04 Qi Huang , Furong Ye , Ananta Shahane , Thomas Bäck , Niki van Stein

As opposed to general English, many concepts in biomedical terminology have been designed in recent history by biomedical professionals with the goal of being precise and concise. This is often achieved by concatenating meaningful…

Computation and Language · Computer Science 2023-07-11 Bernal Jiménez Gutiérrez , Huan Sun , Yu Su

Clinician scheduling remains a persistent challenge due to limited clinical resources and fluctuating demands. This complexity is especially acute in large academic anesthesiology departments as physicians balance responsibilities across…

Optimization and Control · Mathematics 2025-10-03 Anjali Jha , Wanqing Chen , Maxim Eckmann , Ian Stockwell , Jianwu Wang , Kai Sun

Multimodal models are ubiquitous, yet existing explainability methods are often single-modal, architecture-dependent, or too computationally expensive to run at scale. We introduce LEMON (Local Explanations via Modality-aware OptimizatioN),…

Machine Learning · Computer Science 2026-02-04 Yu Qin , Phillip Sloan , Raul Santos-Rodriguez , Majid Mirmehdi , Telmo de Menezes e Silva Filho

Large Language Models (LLMs) exploit fine-tuning as a technique to adapt to diverse goals, thanks to task-specific training data. Task specificity should go hand in hand with domain orientation, that is, the specialization of an LLM to…

Computation and Language · Computer Science 2023-09-20 Teodoro Baldazzi , Luigi Bellomarini , Stefano Ceri , Andrea Colombo , Andrea Gentili , Emanuel Sallinger

Large Language Models (LLMs), such as GPT3.5, have exhibited remarkable proficiency in comprehending and generating natural language. On the other hand, medical assistants hold the potential to offer substantial benefits for individuals.…

Computation and Language · Computer Science 2024-04-05 Kai Zhang , Yangyang Kang , Fubang Zhao , Xiaozhong Liu

Large Language Models (LLMs) have significantly advanced natural language processing (NLP) with their impressive language understanding and generation capabilities. However, their performance may be suboptimal for domain-specific tasks that…

Computation and Language · Computer Science 2023-05-19 Ziyang Luo , Can Xu , Pu Zhao , Xiubo Geng , Chongyang Tao , Jing Ma , Qingwei Lin , Daxin Jiang

Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of…

Computation and Language · Computer Science 2024-08-23 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

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