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Proposals to determine biomolecular structures from diffraction experiments using femtosecond X-ray free-electron laser (XFEL) pulses involve a conflict between the incident brightness required to achieve diffraction-limited atomic…

Optics · Physics 2015-05-19 Harry M. Quiney , Keith A. Nugent

X-ray free-electron lasers (XFELs) as the world's brightest light sources provide ultrashort X-ray pulses with a duration typically in the order of femtoseconds. Recently, they have approached and entered the attosecond regime, which holds…

Accelerator-based X-ray free-electron lasers (XFELs) are the latest addition to the revolutionary tools of discovery for the 21st century. The two major components of an XFEL are an accelerator-produced electron beam and a magnetic…

Diffraction imaging of non-equilibrium dynamics at atomic resolution is becoming possible with X-ray free-electron lasers. However, there are unresolved problems with applying this method to objects that are confined in only one dimension.…

Strongly Correlated Electrons · Physics 2018-02-19 Kenneth R. Beyerlein

In single particle coherent x-ray diffraction imaging experiments, performed at x-ray free-electron lasers (XFELs), samples are exposed to intense x-ray pulses to obtain single-shot diffraction patterns. The high intensity induces…

Atomic and Molecular Clusters · Physics 2013-01-29 U. Lorenz , N. M. Kabachnik , E. Weckert , I. A. Vartanyants

X-ray Free Electron Lasers (XFELs) have been proven to generate short and powerful radiation pulses allowing for a wide class of novel experiments. If an XFEL facility supports the generation of two X-ray pulses with different wavelengths…

Accelerator Physics · Physics 2017-06-05 Gianluca Geloni , Vitali Kocharyan , Tommaso Mazza , Michael Meyer , Evgeni Saldin , Svitozar Serkez

We propose a technique, to be used for time-resolved pump-probe experiments, for timing an x-ray free electron laser (XFEL) to a high-power conventional laser with femtosecond accuracy. Our method takes advantage of the same electron bunch…

Accelerator Physics · Physics 2009-11-13 Gianluca Geloni , Evgeni Saldin , Evgeni Schneidmiller , Mikhail Yurkov

Single-particle imaging experiments of biomolecules at x-ray free-electron lasers (XFELs) require processing of hundreds of thousands (or more) of images that contain very few x-rays. Each low-flux image of the diffraction pattern is…

Instrumentation and Detectors · Physics 2012-03-16 Hugh T. Philipp , Kartik Ayyer , Mark W. Tate , Veit Elser , Sol M. Gruner

Current Flash X-ray single-particle diffraction Imaging (FXI) experiments, which operate on modern X-ray Free Electron Lasers (XFELs), can record millions of interpretable diffraction patterns from individual biomolecules per day. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-02-20 Jing Liu , Gijs van der Schot , Stefan Engblom

X-ray photoelectron diffraction is a powerful tool for determining the structure of clean and adsorbate-covered surfaces. Extending the technique into the ultrafast time domain will open the door to studies as diverse as the direct…

X-ray Free-Electron Lasers (XFELs) deliver X-ray pulses with a coherent flux that is approximately eight orders of magnitude greater than that available from a modern third generation synchrotron source. The power density in an XFEL pulse…

Dynamical diffraction effects in single crystals produce highly monochromatic parallel X-ray beams with a mutual separation of a few micrometer and a time-delay of a few fs -the so-called echoes. This ultrafast diffraction effect is used at…

X-ray free-electron lasers (XFELs) utilize high-density and high-energy electron bunches which are well-suited to produce Compton back-scattering radiation. Here we study back-scattered radiation pulses produced by the interaction of XFEL…

Accelerator Physics · Physics 2023-09-28 Eugene Bulyak , Svitozar Serkez , Gianluca Aldo Geloni

Modern Flash X-ray diffraction Imaging (FXI) acquires diffraction signals from single biomolecules at a high repetition rate from X-ray Free Electron Lasers (XFELs), easily obtaining millions of 2D diffraction patterns from a single…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Jing Liu , Stefan Engblom , Carl Nettelblad

Sub-angstrom spatial resolution of electron density coupled with sub-femtosecond temporal resolution is required to directly observe the dynamics of the electronic structure of a molecule after photoinitiation or some other ultrafast…

X-ray free electron lasers (XFELs) are the new generation of particle accelerator-based light sources, capable of producing tunable, high-power X-ray pulses that are increasingly vital across various scientific disciplines. Recently,…

Accelerator Physics · Physics 2025-02-03 Liuyang Wu , Zihan Zhu , Bingyang Yan , Jiawei Yan , Haixiao Deng

A channel-cut Si(111) crystal with a channel width of 90 $\mu$m was developed for achieving reflection self-seeding in hard X-ray free-electron lasers (XFELs). With the crystal, a monochromatic seed pulse is produced from a broadband XFEL…

Instrumentation and Detectors · Physics 2018-11-06 Taito Osaka , Ichiro Inoue , Ryota Kinjo , Takashi Hirano , Yuki Morioka , Yasuhisa Sano , Kazuto Yamauchi , Makina Yabashi

The advent of X-ray free-electron lasers (XFELs) has revolutionized fundamental science, from atomic to condensed matter physics, from chemistry to biology, giving researchers access to X-rays with unprecedented brightness, coherence, and…

Mesoscale and Nanoscale Physics · Physics 2022-10-27 Nanna Zhou Hagström , Michael Schneider , Nico Kerber , Alexander Yaroslavtsev , Erick Burgos Parra , Marijan Beg , Martin Lang , Christian M. Günther , Boris Seng , Fabian Kammerbauer , Horia Popescu , Matteo Pancaldi , Kumar Neeraj , Debanjan Polley , Rahul Jangid , Stjepan B. Hrkac , Sheena K. K. Patel , Sergei Ovcharenko , Diego Turenne , Dmitriy Ksenzov , Christine Boeglin , Igor Pronin , Marina Baidakova , Clemens von Korff Schmising , Martin Borchert , Boris Vodungbo , Kai Chen , Chen Luo , Florin Radu , Leonard Müller , Miriam Martínez Flórez , André Philippi-Kobs , Matthias Riepp , Wojciech Roseker , Gerhard Grübel , Robert Carley , Justine Schlappa , Benjamin Van Kuiken , Rafael Gort , Laurent Mercadier , Naman Agarwal , Loïc Le Guyader , Giuseppe Mercurio , Martin Teichmann , Jan Torben Delitz , Alexander Reich , Carsten Broers , David Hickin , Carsten Deiter , James Moore , Dimitrios Rompotis , Jinxiong Wang , Daniel Kane , Sandhya Venkatesan , Joachim Meier , Florent Pallas , Tomasz Jezynski , Maximilian Lederer , Djelloul Boukhelef , Janusz Szuba , Krzysztof Wrona , Steffen Hauf , Jun Zhu , Martin Bergemann , Ebad Kamil , Thomas Kluyver , Robert Rosca , Michał Spirzewski , Markus Kuster , Monica Turcato , David Lomidze , Andrey Samartsev , Jan Engelke , Matteo Porro , Stefano Maffessanti , Karsten Hansen , Florian Erdinger , Peter Fischer , Carlo Fiorini , Andrea Castoldi , Massimo Manghisoni , Cornelia Beatrix Wunderer , Eric E. Fullerton , Oleg G. Shpyrko , Christian Gutt , Cecilia Sanchez-Hanke , Hermann A. Dürr , Ezio Iacocca , Hans T. Nembach , Mark W. Keller , Justin M. Shaw , Thomas J. Silva , Roopali Kukreja , Hans Fangohr , Stefan Eisebitt , Mathias Kläui , Nicolas Jaouen , Andreas Scherz , Stefano Bonetti , Emmanuelle Jal

The European X-ray Free Electron Laser (XFEL.EU) will provide unprecedented peak brilliance and ultra-short and spatially coherent X-ray pulses in an energy range of 0.25 to 25 keV . The pulse timing structure is unique with a burst of 2700…

X-ray free electron laser (XFEL) experiments have brought unique capabilities and opened new directions in research, such as creating new states of matter or directly measuring atomic motion. One such area is the ability to use finely…