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The integration of large language models (LLMs) into virtual reality (VR) environments has opened new pathways for creating more immersive and interactive digital humans. By leveraging the generative capabilities of LLMs alongside…

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

VR simulation in Health Professions (HP) education demonstrates huge potential, but fixed learning content with little customization limits its application beyond lab environments. To address these limitations in the context of VR for…

Human-Computer Interaction · Computer Science 2025-03-04 Xiuqi Tommy Zhu , Heidi Cheerman , Minxin Cheng , Sheri Kiami , Leanne Chukoskie , Eileen McGivney

Objective Structured Clinical Examinations (OSCEs) are essential for medical training, but they require significant resources, including professional actors and expert medical feedback. Although Large Language Models (LLMs) have introduced…

Human-Computer Interaction · Computer Science 2025-08-20 Henrik Voigt , Yurina Sugamiya , Kai Lawonn , Sina Zarrieß , Atsuo Takanishi

Simulations constitute a fundamental component of medical and nursing education and traditionally employ standardized patients (SP) and high-fidelity manikins to develop clinical reasoning and communication skills. However, these methods…

Human-Computer Interaction · Computer Science 2025-10-23 Akilan Amithasagaran , Sagnik Dakshit , Bhavani Suryadevara , Lindsey Stockton

The purpose of this review article is to provide a bibliographical as well as evidence-based visual guide regarding the effect of ``Uncanny Valley'' (UV) and how it profoundly influences medical virtual reality simulation-based training.…

Graphics · Computer Science 2026-01-01 Eleni Grigoriou , Manos Kamarianakis , George Papagiannakis

Effective patient communication is pivotal in healthcare, yet traditional medical training often lacks exposure to diverse, challenging interpersonal dynamics. To bridge this gap, this study proposes the use of Large Language Models (LLMs)…

Mental health challenges are rising globally, while traditional support services face limited availability and high costs. Large language models offer potential for conversational support, but often lack personalization, empathy, and…

Human-Computer Interaction · Computer Science 2026-04-24 Truong Le Minh Toan , Dieu Bang Mach , Tan Duy Le , Nguyen Tan Viet Tuyen

Simulated Patients (SPs) play a crucial role in clinical medical education by providing realistic scenarios for student practice. However, the high cost of training and hiring qualified SPs, along with the heavy workload and potential risks…

Computation and Language · Computer Science 2024-04-26 Yanzeng Li , Cheng Zeng , Jialun Zhong , Ruoyu Zhang , Minhao Zhang , Lei Zou

The integration of Large Language Models (LLMs) into Virtual Reality (VR) games marks a paradigm shift in the design of immersive, adaptive, and intelligent digital experiences. This paper presents a comprehensive review of recent research…

Human-Computer Interaction · Computer Science 2025-11-24 Süeda Özkaya , Santiago Berrezueta-Guzman , Stefan Wagner

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

Immersive virtual reality (VR) offers affordances that may reduce cognitive complexity in binary reverse engineering (RE), enabling embodied and external cognition to augment the RE process through enhancing memory, hypothesis testing, and…

Human-Computer Interaction · Computer Science 2025-08-20 Dennis Brown , Samuel Mulder

Effective communication training is essential to preparing nurses for high-quality patient care. While standardized patient (SP) simulations provide valuable experiential learning, they are often costly and inflexible. Virtual patient (VP)…

Computation and Language · Computer Science 2025-06-03 Keyeun Lee , Seolhee Lee , Esther Hehsun Kim , Yena Ko , Jinsu Eun , Dahee Kim , Hyewon Cho , Haiyi Zhu , Robert E. Kraut , Eunyoung Suh , Eun-mee Kim , Hajin Lim

We present a virtual reality (VR) environment featuring conversational avatars powered by a locally-deployed LLM, integrated with automatic speech recognition (ASR), text-to-speech (TTS), and lip-syncing. Through a pilot study, we explored…

Human-Computer Interaction · Computer Science 2025-01-08 Mykola Maslych , Christian Pumarada , Amirpouya Ghasemaghaei , Joseph J. LaViola

Virtual, Augmented, and eXtended Reality (VR/AR/XR) technologies are increasingly recognized for their applications in training, diagnostics, and psychological research, particularly in high-risk and highly regulated environments. In this…

Doctor-patient consultations require multi-turn, context-aware communication tailored to diverse patient personas. Training or evaluating doctor LLMs in such settings requires realistic patient interaction systems. However, existing…

Artificial Intelligence · Computer Science 2025-10-30 Daeun Kyung , Hyunseung Chung , Seongsu Bae , Jiho Kim , Jae Ho Sohn , Taerim Kim , Soo Kyung Kim , Edward Choi

Medical large language models (LLMs) achieve impressive performance on standardized benchmarks, yet these evaluations fail to capture the complexity of real clinical encounters where patients exhibit memory gaps, limited health literacy,…

Artificial Intelligence · Computer Science 2026-04-14 Sina Mansouri , Mohit Marvania , Vibhavari Ashok Shihorkar , Han Ngoc Tran , Kazhal Shafiei , Mehrdad Fazli , Yikuan Li , Ziwei Zhu

The advent of immersive Virtual Reality applications has transformed various domains, yet their integration with advanced artificial intelligence technologies like Visual Language Models remains underexplored. This study introduces a…

Robotics · Computer Science 2024-08-06 Mikhail Konenkov , Artem Lykov , Daria Trinitatova , Dzmitry Tsetserukou

Virtual reality (VR) and interactive 3D visualization systems have enhanced educational experiences and environments, particularly in complicated subjects such as anatomy education. VR-based systems surpass the potential limitations of…

Mental health issues are worsening in today's competitive society, such as depression and anxiety. Traditional healings like counseling and chatbots fail to engage effectively, they often provide generic responses lacking emotional depth.…

Computation and Language · Computer Science 2025-09-12 Yujia Chen , Changsong Li , Yiming Wang , Tianjie Ju , Qingqing Xiao , Nan Zhang , Zifan Kong , Peng Wang , Binyu Yan
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