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The early detection and prediction of cardiovascular diseases are crucial for reducing the severe morbidity and mortality associated with these conditions worldwide. A multi-headed self-attention mechanism, widely used in natural language…

Graphs can be leveraged to model polyphonic multitrack symbolic music, where notes, chords and entire sections may be linked at different levels of the musical hierarchy by tonal and rhythmic relationships. Nonetheless, there is a lack of…

Sound · Computer Science 2023-07-28 Emanuele Cosenza , Andrea Valenti , Davide Bacciu

We present CardiacGen, a Deep Learning framework for generating synthetic but physiologically plausible cardiac signals like ECG. Based on the physiology of cardiovascular system function, we propose a modular hierarchical generative model…

Machine Learning · Computer Science 2022-11-16 Tushar Agarwal , Emre Ertin

We introduce PartCrafter, the first structured 3D generative model that jointly synthesizes multiple semantically meaningful and geometrically distinct 3D meshes from a single RGB image. Unlike existing methods that either produce…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Yuchen Lin , Chenguo Lin , Panwang Pan , Honglei Yan , Yiqiang Feng , Yadong Mu , Katerina Fragkiadaki

Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

Machine Learning · Computer Science 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Current text-to-3D methods excel at generating single objects but falter on compositional prompts. We argue this failure is fundamental to their optimization schedules, as simultaneous or iterative heuristics predictably collapse under a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Utkarsh Nath , Rajeev Goel , Rahul Khurana , Kyle Min , Mark Ollila , Pavan Turaga , Varun Jampani , Tejaswi Gowda

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright

Recent text-to-image generative models can generate high-fidelity images from text prompts. However, these models struggle to consistently generate the same objects in different contexts with the same appearance. Consistent object…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Alec Helbling , Evan Montoya , Duen Horng Chau

Generating molecular structures with desired properties is a critical task with broad applications in drug discovery and materials design. We propose 3M-Diffusion, a novel multi-modal molecular graph generation method, to generate diverse,…

Machine Learning · Computer Science 2024-10-04 Huaisheng Zhu , Teng Xiao , Vasant G Honavar

Structure-based drug design (SBDD), which aims to generate molecules that can bind tightly to the target protein, is an essential problem in drug discovery, and previous approaches have achieved initial success. However, most existing…

Machine Learning · Computer Science 2024-04-04 Xinze Li , Penglei Wang , Tianfan Fu , Wenhao Gao , Chengtao Li , Leilei Shi , Junhong Liu

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye

Cyclic peptides, characterized by geometric constraints absent in linear peptides, offer enhanced biochemical properties, presenting new opportunities to address unmet medical needs. However, designing target-specific cyclic peptides…

Machine Learning · Computer Science 2025-07-15 Dapeng Jiang , Xiangzhe Kong , Jiaqi Han , Mingyu Li , Rui Jiao , Wenbing Huang , Stefano Ermon , Jianzhu Ma , Yang Liu

Finding appropriate low dimensional representations of high-dimensional multi-modal data can be challenging, since each modality embodies unique deformations and interferences. In this paper, we address the problem using manifold learning,…

Signal Processing · Electrical Eng. & Systems 2018-08-23 Tal Shnitzer , Mirela Ben-Chen , Leonidas Guibas , Ronen Talmon , Hau-Tieng Wu

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational modeling of atrioventricular valves has advanced…

Tissues and Organs · Quantitative Biology 2022-02-01 Wensi Wu , Stephen Ching , Steve A. Maas , Andras Lasso , Patricia Sabin , Jeffrey A. Weiss , Matthew A. Jolley

The complex structure of the heart leads to significant challenges in echocardiography, especially in acquisition cardiac ultrasound images. Successful echocardiography requires a thorough understanding of the structures on the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Haojun Jiang , Meng Li , Zhenguo Sun , Ning Jia , Yu Sun , Shaqi Luo , Shiji Song , Gao Huang

Cardiac segmentation is in great demand for clinical practice. Due to the enormous labor of manual delineation, unsupervised segmentation is desired. The ill-posed optimization problem of this task is inherently challenging, requiring…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 Sihan Wang , Fuping Wu , Lei Li , Zheyao Gao , Byung-Woo Hong , Xiahai Zhuang

Accurate analysis of cardiac motion is crucial for evaluating cardiac function. While dynamic cardiac magnetic resonance imaging (CMR) can capture detailed tissue motion throughout the cardiac cycle, the fine-grained 4D cardiac motion…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Xueming Fu , Pei Wu , Yingtai Li , Xin Luo , Zihang Jiang , Junhao Mei , Jian Lu , Gao-Jun Teng , S. Kevin Zhou

This paper explores the modeling method of polyphonic music sequence. Due to the great potential of Transformer models in music generation, controllable music generation is receiving more attention. In the task of polyphonic music, current…

Sound · Computer Science 2023-11-29 Jiuyang Zhou , Tengfei Niu , Hong Zhu , Xingping Wang
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