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Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Yadan Li , Mohammad Ali Armin , Simon Denman , David Ahmedt-Aristizabal

Electroanatomical mapping, a keystone diagnostic tool in cardiac electrophysiology studies, can provide high-density maps of the local electric properties of the tissue. It is therefore tempting to use such data to better individualize…

Optimization and Control · Mathematics 2021-02-03 Thomas Grandits , Simone Pezzuto , Jolijn M. Lubrecht , Thomas Pock , Gernot Plank , Rolf Krause

Generating symphonic music requires simultaneously managing high-level structural form and dense, multi-track orchestration. Existing symbolic models often struggle with a "complexity-control imbalance", in which scaling bottlenecks limit…

Sound · Computer Science 2026-04-29 Xuzheng He , Nan Nan , Zhilin Wang , Ziyue Kang , Zhuoru Mo , Ao Li , Yu Pan , Xiaobing Li , Feng Yu , Xiaohong Guan

The interaction of a protein with its environment can be understood and controlled via its 3D structure. Experimental methods for protein structure determination, such as X-ray crystallography or cryogenic electron microscopy, shed light on…

Machine Learning · Computer Science 2025-04-24 Axel Levy , Eric R. Chan , Sara Fridovich-Keil , Frédéric Poitevin , Ellen D. Zhong , Gordon Wetzstein

One of the goals of personalized medicine is to tailor diagnostics to individual patients. Diagnostics are performed in practice by measuring quantities, called biomarkers, that indicate the existence and progress of a disease. In common…

Medical Physics · Physics 2024-12-20 Diego Renner , Georgios Kissas

Inverse design, where we seek to design input variables in order to optimize an underlying objective function, is an important problem that arises across fields such as mechanical engineering to aerospace engineering. Inverse design is…

Machine Learning · Computer Science 2024-03-12 Tailin Wu , Takashi Maruyama , Long Wei , Tao Zhang , Yilun Du , Gianluca Iaccarino , Jure Leskovec

In this work, we introduce AutoFragDiff, a fragment-based autoregressive diffusion model for generating 3D molecular structures conditioned on target protein structures. We employ geometric vector perceptrons to predict atom types and…

Biomolecules · Quantitative Biology 2024-01-12 Mahdi Ghorbani , Leo Gendelev , Paul Beroza , Michael J. Keiser

Cellular electron cryo-tomography enables the 3D visualization of cellular organization in the near-native state and at submolecular resolution. However, the contents of cellular tomograms are often complex, making it difficult to…

Quantitative Methods · Quantitative Biology 2017-12-29 Xiangrui Zeng , Miguel Ricardo Leung , Tzviya Zeev-Ben-Mordehai , Min Xu

Deep learning models often need sufficient supervision (i.e. labelled data) in order to be trained effectively. By contrast, humans can swiftly learn to identify important anatomy in medical images like MRI and CT scans, with minimal…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Xiao Liu , Pedro Sanchez , Spyridon Thermos , Alison Q. O'Neil , Sotirios A. Tsaftaris

Accurate cardiac anatomy modeling requires the model to be able to handle intricate interrelations among structures. In this paper, we propose VecHeart, a unified framework for holistic reconstruction and generation of four-chamber cardiac…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Yihong Chen , Pascal Fua

Vessels are complex structures in the body that have been studied extensively in multiple representations. While voxelization is the most common of them, meshes and parametric models are critical in various applications due to their…

Patterns, which are collections of elements arranged in regular or near-regular arrangements, are an important graphic art form and widely used due to their elegant simplicity and aesthetic appeal. When a pattern is encoded as a flat image…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Pradyumna Reddy , Paul Guerrero , Matt Fisher , Wilmot Li , Miloy J. Mitra

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

In this work, we provide a performance comparison between the Balancing Domain Decomposition by Constraints (BDDC) and the Algebraic Multigrid (AMG) preconditioners for cardiac mechanics on both structured and unstructured finite element…

Numerical Analysis · Mathematics 2022-08-15 Nicolás A. Barnafi , Luca F. Pavarino , Simone Scacchi

Noninvasive reconstruction of cardiac transmembrane potential (TMP) from surface electrocardiograms (ECG) involves an ill-posed inverse problem. Model-constrained regularization is powerful for incorporating rich physiological knowledge…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , Jwala Dhamala , Prashnna Kumar Gyawali , John L Sapp , B. Milan Horacek , Linwei Wang

Scientists, engineers, biologists, and technology specialists universally leverage image segmentation to extract shape ensembles containing many thousands of curves representing patterns in observations and measurements. These large curve…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Zachary Grey , Nicholas Fisher , Andrew Glaws

Generating high-quality and diverse human images is an important yet challenging task in vision and graphics. However, existing generative models often fall short under the high diversity of clothing shapes and textures. Furthermore, the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-01 Yuming Jiang , Shuai Yang , Haonan Qiu , Wayne Wu , Chen Change Loy , Ziwei Liu

This study proposes an end-to-end unsupervised diffeomorphic deformable registration framework based on moving mesh parameterization. Using this parameterization, a deformation field can be modeled with its transformation Jacobian…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Ameneh Sheikhjafari , Deepa Krishnaswamy , Michelle Noga , Nilanjan Ray , Kumaradevan Punithakumar

We introduce SCORES, a recursive neural network for shape composition. Our network takes as input sets of parts from two or more source 3D shapes and a rough initial placement of the parts. It outputs an optimized part structure for the…

Graphics · Computer Science 2018-09-17 Chenyang Zhu , Kai Xu , Siddhartha Chaudhuri , Renjiao Yi , Hao Zhang

While modern diffusion models excel at generating high-quality and diverse images, they still struggle with high-fidelity compositional and multimodal control, particularly when users simultaneously specify text prompts, subject references,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Yusuf Dalva , Guocheng Gordon Qian , Maya Goldenberg , Tsai-Shien Chen , Kfir Aberman , Sergey Tulyakov , Pinar Yanardag , Kuan-Chieh Jackson Wang
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