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This paper investigates the challenges of developing large language models (LLMs) proficient in both multilingual understanding and medical knowledge. We demonstrate that simply translating medical data does not guarantee strong performance…

Computation and Language · Computer Science 2025-01-20 Nada Saadi , Tathagata Raha , Clément Christophe , Marco AF Pimentel , Ronnie Rajan , Praveen K Kanithi

Biomedical Named Entity Recognition (NER) is a fundamental task of Biomedical Natural Language Processing for extracting relevant information from biomedical texts, such as clinical records, scientific publications, and electronic health…

Computation and Language · Computer Science 2023-12-27 Fahime Shahrokh , Nasser Ghadiri , Rasoul Samani , Milad Moradi

Recently, the performance of Pre-trained Language Models (PLMs) has been significantly improved by injecting knowledge facts to enhance their abilities of language understanding. For medical domains, the background knowledge sources are…

Computation and Language · Computer Science 2021-08-23 Taolin Zhang , Zerui Cai , Chengyu Wang , Minghui Qiu , Bite Yang , Xiaofeng He

In precision medicine, quantitative multi-omic features, topological context, and textual biological knowledge play vital roles in identifying disease-critical signaling pathways and targets. Existing pipelines capture only part of…

Artificial Intelligence · Computer Science 2025-12-17 Heming Zhang , Di Huang , Wenyu Li , Michael Province , Yixin Chen , Philip Payne , Fuhai Li

Knowledge graph completion (KGC) aims to predict missing triples in knowledge graphs (KGs) by leveraging existing triples and textual information. Recently, generative large language models (LLMs) have been increasingly employed for graph…

Artificial Intelligence · Computer Science 2025-11-11 Yongkang Xiao , Sinian Zhang , Yi Dai , Huixue Zhou , Jue Hou , Jie Ding , Rui Zhang

The exponential growth of biomedical texts such as biomedical literature and electronic health records (EHRs), poses a significant challenge for clinicians and researchers to access clinical information efficiently. To tackle this…

Computation and Language · Computer Science 2023-07-17 Qianqian Xie , Zheheng Luo , Benyou Wang , Sophia Ananiadou

Domain experts often rely on most recent knowledge for apprehending and disseminating specific biological processes that help them design strategies for developing prevention and therapeutic decision-making in various disease scenarios. A…

Computation and Language · Computer Science 2023-11-21 Md. Rezaul Karim , Lina Molinas Comet , Md Shajalal , Oya Deniz Beyan , Dietrich Rebholz-Schuhmann , Stefan Decker

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Corpus distillation for biomedical large language models (LLMs) seeks to address the pressing challenge of insufficient quantity and quality in open-source annotated scientific corpora, which remains a bottleneck for effective LLM training…

Computation and Language · Computer Science 2025-12-19 Meng Xiao , Xunxin Cai , Qingqing Long , Chengrui Wang , Yuanchun Zhou , Hengshu Zhu

Deploying Large Language Models (LLMs) for healthcare question answering requires robust methods to ensure accuracy and reliability. This work introduces Query-Based Retrieval Augmented Generation (QB-RAG), a framework for enhancing…

Machine Learning · Computer Science 2025-07-31 Eric Yang , Jonathan Amar , Jong Ha Lee , Bhawesh Kumar , Yugang Jia

Language model (LM) pretraining can learn various knowledge from text corpora, helping downstream tasks. However, existing methods such as BERT model a single document, and do not capture dependencies or knowledge that span across…

Computation and Language · Computer Science 2022-03-31 Michihiro Yasunaga , Jure Leskovec , Percy Liang

Recent advances in image-text pretraining have significantly enhanced visual understanding by aligning visual and textual representations. Contrastive Language-Image Pretraining (CLIP) has played a pivotal role in multimodal learning.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Zihan Li , Yiqing Wang , Sina Farsiu , Paul Kinahan

Recent development in Retrieval-Augmented Large Language Models (LLMs) have shown great promise in biomedical applications. How ever, a critical gap persists in reliably evaluating their curation ability the process by which models select…

Computation and Language · Computer Science 2025-08-07 Hanmeng Zhong , Linqing Chen , Wentao Wu , Weilei Wang

Knowledge Graph Embeddings (KGE) have become a quite popular class of models specifically devised to deal with ontologies and graph structure data, as they can implicitly encode statistical dependencies between entities and relations in a…

Artificial Intelligence · Computer Science 2023-03-27 Michelangelo Diligenti , Francesco Giannini , Stefano Fioravanti , Caterina Graziani , Moreno Falaschi , Giuseppe Marra

With the advent of pretrained language models (LMs), increasing research efforts have been focusing on infusing commonsense and domain-specific knowledge to prepare LMs for downstream tasks. These works attempt to leverage knowledge graphs,…

Computation and Language · Computer Science 2023-05-16 Shangbin Feng , Zhaoxuan Tan , Wenqian Zhang , Zhenyu Lei , Yulia Tsvetkov

Pretraining a language model (LM) on text has been shown to help various downstream NLP tasks. Recent works show that a knowledge graph (KG) can complement text data, offering structured background knowledge that provides a useful scaffold…

Computation and Language · Computer Science 2022-10-20 Michihiro Yasunaga , Antoine Bosselut , Hongyu Ren , Xikun Zhang , Christopher D Manning , Percy Liang , Jure Leskovec

This comprehensive review aims to provide an overview of the current state of Healthcare Knowledge Graphs (HKGs), including their construction, utilization models, and applications across various healthcare and biomedical research domains.…

Recent advancements in Large Language Models (LLMs) have showcased their proficiency in answering natural language queries. However, their effectiveness is hindered by limited domain-specific knowledge, raising concerns about the…

Vision-language models have become increasingly powerful for tasks that require an understanding of both visual and linguistic elements, bridging the gap between these modalities. In the context of multimodal clinical AI, there is a growing…

Computation and Language · Computer Science 2024-04-30 Masoud Monajatipoor , Zi-Yi Dou , Aichi Chien , Nanyun Peng , Kai-Wei Chang

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

Machine Learning · Computer Science 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam