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Seeking dietary guidance often requires navigating complex professional knowledge while accommodating individual health conditions. Knowledge Graphs (KGs) offer structured and interpretable nutritional information, whereas Large Language…

Human-Computer Interaction · Computer Science 2025-04-22 Fan Gao , Xinjie Zhao , Ding Xia , Zhongyi Zhou , Rui Yang , Jinghui Lu , Hang Jiang , Chanjun Park , Irene Li

Large language models (LLMs) used in medical applications are known to be prone to exhibiting biased and unfair patterns. Prior to deploying these in clinical decision-making, it is crucial to identify such bias patterns to enable effective…

Artificial Intelligence · Computer Science 2025-12-23 Farzana Islam Adiba , Rahmatollah Beheshti

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

Large language models (LLMs) frequently generate confident yet factually incorrect content when used for language generation (a phenomenon often known as hallucination). Retrieval augmented generation (RAG) tries to reduce factual errors by…

Information Retrieval · Computer Science 2026-04-01 Dobrik Georgiev , Kheeran Naidu , Alberto Cattaneo , Federico Monti , Carlo Luschi , Daniel Justus

Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

Computation and Language · Computer Science 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

Biomedical entity linking (BEL) is the task of grounding entity mentions to a knowledge base. It plays a vital role in information extraction pipelines for the life sciences literature. We review recent work in the field and find that, as…

Computation and Language · Computer Science 2023-08-23 Samuele Garda , Leon Weber-Genzel , Robert Martin , Ulf Leser

Pre-trained language models have attracted increasing attention in the biomedical domain, inspired by their great success in the general natural language domain. Among the two main branches of pre-trained language models in the general…

Computation and Language · Computer Science 2023-04-04 Renqian Luo , Liai Sun , Yingce Xia , Tao Qin , Sheng Zhang , Hoifung Poon , Tie-Yan Liu

Although achieving great success, Large Language Models (LLMs) usually suffer from unreliable hallucinations. Although language attribution can be a potential solution, there are no suitable benchmarks and evaluation metrics to attribute…

Computation and Language · Computer Science 2024-05-24 Xinze Li , Yixin Cao , Liangming Pan , Yubo Ma , Aixin Sun

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Term clustering is important in biomedical knowledge graph construction. Using similarities between terms embedding is helpful for term clustering. State-of-the-art term embeddings leverage pretrained language models to encode terms, and…

Computation and Language · Computer Science 2022-04-04 Sihang Zeng , Zheng Yuan , Sheng Yu

Integrating large language models (LLMs) into healthcare holds great potential but faces challenges. Pre-training LLMs from scratch for domains like medicine is resource-heavy and often unfeasible. On the other hand, sole reliance on…

Computation and Language · Computer Science 2024-04-18 Qichen Ye , Junling Liu , Dading Chong , Peilin Zhou , Yining Hua , Fenglin Liu , Meng Cao , Ziming Wang , Xuxin Cheng , Zhu Lei , Zhenhua Guo

Large Language Models (LLMs) have greatly contributed to the development of adaptive intelligent agents and are positioned as an important way to achieve Artificial General Intelligence (AGI). However, LLMs are prone to produce factually…

Computation and Language · Computer Science 2024-08-29 Weijian Xie , Xuefeng Liang , Yuhui Liu , Kaihua Ni , Hong Cheng , Zetian Hu

Word embeddings play a significant role in today's Natural Language Processing tasks and applications. While pre-trained models may be directly employed and integrated into existing pipelines, they are often fine-tuned to better fit with…

Computation and Language · Computer Science 2022-11-10 Denys Amore Bondarenko , Roger Ferrod , Luigi Di Caro

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Large Language Models (LLMs) have demonstrated impressive capabilities across natural language processing tasks. However, their application to specialized domains such as medicine and biology requires further optimization to ensure factual…

Computation and Language · Computer Science 2025-02-06 Seonok Kim

Recent advances in large language models (LLMs) and biomedical foundation models (BioFMs) have achieved strong results in biological text reasoning, molecular modeling, and single-cell analysis, yet they remain siloed in disjoint embedding…

Quantitative Methods · Quantitative Biology 2025-10-03 Ching-Huei Tsou , Michal Ozery-Flato , Ella Barkan , Diwakar Mahajan , Ben Shapira

Clinicians are increasingly looking towards machine learning to gain insights about patient evolutions. We propose a novel approach named Multi-Modal UMLS Graph Learning (MMUGL) for learning meaningful representations of medical concepts…

Machine Learning · Computer Science 2024-02-07 Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Recent advances in large language models (LLMs) have unlocked powerful reasoning and decision-making capabilities. However, their inherent dependence on static parametric memory fundamentally limits their adaptability, factual accuracy, and…

Information Retrieval · Computer Science 2025-08-07 Xinkui Zhao , Haode Li , Yifan Zhang , Guanjie Cheng , Yueshen Xu

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Evaluating the open-form textual responses generated by Large Language Models (LLMs) typically requires measuring the semantic similarity of the response to a (human generated) reference. However, there is evidence that current semantic…

Artificial Intelligence · Computer Science 2025-11-26 Qiyao Wei , Edward Morrell , Lea Goetz , Mihaela van der Schaar
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