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Knowledge graph completion (KGC) aims to infer new knowledge and make predictions from knowledge graphs. Recently, large language models (LLMs) have exhibited remarkable reasoning capabilities. LLM-enhanced KGC methods primarily focus on…

Computation and Language · Computer Science 2025-09-03 Yu Liu , Yanan Cao , Xixun Lin , Yanmin Shang , Shi Wang , Shirui Pan

Pre-trained language models (PLMs) have achieved remarkable success on various natural language understanding tasks. Simple fine-tuning of PLMs, on the other hand, might be suboptimal for domain-specific tasks because they cannot possibly…

Computation and Language · Computer Science 2022-08-05 Minki Kang , Jinheon Baek , Sung Ju Hwang

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

The overwhelming amount of biomedical scientific texts calls for the development of effective language models able to tackle a wide range of biomedical natural language processing (NLP) tasks. The most recent dominant approaches are…

Computation and Language · Computer Science 2021-04-21 Giacomo Miolo , Giulio Mantoan , Carlotta Orsenigo

Entities lie in the heart of biomedical natural language understanding, and the biomedical entity linking (EL) task remains challenging due to the fine-grained and diversiform concept names. Generative methods achieve remarkable…

Computation and Language · Computer Science 2022-05-24 Hongyi Yuan , Zheng Yuan , Sheng Yu

Recently, ChatGPT, a representative large language model (LLM), has gained considerable attention due to its powerful emergent abilities. Some researchers suggest that LLMs could potentially replace structured knowledge bases like knowledge…

Computation and Language · Computer Science 2024-01-31 Linyao Yang , Hongyang Chen , Zhao Li , Xiao Ding , Xindong Wu

The increasing reliance on Large Language Models (LLMs) for health information seeking can pose severe risks due to the potential for misinformation and the complexity of these topics. This paper introduces KNOWNET a visualization system…

Human-Computer Interaction · Computer Science 2024-09-27 Youfu Yan , Yu Hou , Yongkang Xiao , Rui Zhang , Qianwen Wang

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

The ability of knowledge graphs to represent complex relationships at scale has led to their adoption for various needs including knowledge representation, question-answering, and recommendation systems. Knowledge graphs are often…

Computation and Language · Computer Science 2023-05-18 Jason Youn , Ilias Tagkopoulos

Biomedical question-answering (QA) has gained increased attention for its capability to provide users with high-quality information from a vast scientific literature. Although an increasing number of biomedical QA datasets has been recently…

Computation and Language · Computer Science 2021-02-17 Gabriele Pergola , Elena Kochkina , Lin Gui , Maria Liakata , Yulan He

The integration of Artificial Intelligence (AI) into the field of drug discovery has been a growing area of interdisciplinary scientific research. However, conventional AI models are heavily limited in handling complex biomedical structures…

Machine Learning · Computer Science 2024-07-25 Zhiqiang Zhong , Anastasia Barkova , Davide Mottin

Existing Protein Language Models (PLMs) often suffer from limited adaptability to multiple tasks and exhibit poor generalization across diverse biological contexts. In contrast, general-purpose Large Language Models (LLMs) lack the…

Machine Learning · Computer Science 2026-02-23 Yujia Wang , Jihong Guan , Wengen Li , Shuigeng Zhou , Xuhong Wang

Medical text learning has recently emerged as a promising area to improve healthcare due to the wide adoption of electronic health record (EHR) systems. The complexity of the medical text such as diverse length, mixed text types, and full…

Computation and Language · Computer Science 2022-10-11 Yong He , Cheng Wang , Shun Zhang , Nan Li , Zhaorong Li , Zhenyu Zeng

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging…

Computation and Language · Computer Science 2023-10-24 Wei Zhu , Xiaoling Wang , Huanran Zheng , Mosha Chen , Buzhou Tang

Multimodal reasoning in Large Language Models (LLMs) struggles with incomplete knowledge and hallucination artifacts, challenges that textual Knowledge Graphs (KGs) only partially mitigate due to their modality isolation. While Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Junming Liu , Siyuan Meng , Yanting Gao , Song Mao , Pinlong Cai , Guohang Yan , Yirong Chen , Zilin Bian , Ding Wang , Botian Shi

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

Document-Level Biomedical Relation Extraction (Bio-RE) aims to identify relations between biomedical entities within extensive texts, serving as a crucial subfield of biomedical text mining. Existing Bio-RE methods struggle with…

Computation and Language · Computer Science 2025-01-10 Yufei Shang , Yanrong Guo , Shijie Hao , Richang Hong

Large Language Models (LLMs) have grown exponentially since the release of ChatGPT. These models have gained attention due to their robust performance on various tasks, including language processing tasks. These models achieve understanding…

Computation and Language · Computer Science 2025-08-11 Ali Sarabadani , Maryam Abdollahi Shamami , Hamidreza Sadeghsalehi , Borhan Asadi , Saba Hesaraki

Within clinical, biomedical, and translational science, an increasing number of projects are adopting graphs for knowledge representation. Graph-based data models elucidate the interconnectedness between core biomedical concepts, enable…

Molecular property prediction is a crucial foundation for drug discovery. In recent years, pre-trained deep learning models have been widely applied to this task. Some approaches that incorporate prior biological domain knowledge into the…

Machine Learning · Computer Science 2024-08-20 Tianyu Zhang , Yuxiang Ren , Chengbin Hou , Hairong Lv , Xuegong Zhang
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