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Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

Intraoperative pathology is pivotal to precision surgery, yet its clinical impact is constrained by diagnostic complexity and the limited availability of high-quality frozen-section data. While computational pathology has made significant…

Breast cancer is one of the leading causes of death among women worldwide. We introduce Mammo-FM, the first foundation model specifically for mammography, pretrained on the largest and most diverse dataset to date - 140,677 patients…

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu

Foundation models in artificial intelligence (AI) are transforming medical imaging by enabling general-purpose feature learning from large-scale, unlabeled datasets. In this work, we introduce BrainFound, a self-supervised foundation model…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Moona Mazher , Geoff J. M. Parker , Daniel C. Alexander

Foundation models, large-scale, pre-trained deep-learning models adapted to a wide range of downstream tasks have gained significant interest lately in various deep-learning problems undergoing a paradigm shift with the rise of these…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Bobby Azad , Reza Azad , Sania Eskandari , Afshin Bozorgpour , Amirhossein Kazerouni , Islem Rekik , Dorit Merhof

Modern medical records include a vast amount of multimodal free text clinical data and imaging data from radiology, cardiology, and digital pathology. Fully mining such big data requires multitasking; otherwise, occult but important aspects…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Chuang Niu , Qing Lyu , Christopher D. Carothers , Parisa Kaviani , Josh Tan , Pingkun Yan , Mannudeep K. Kalra , Christopher T. Whitlow , Ge Wang

Prostate cancer (PCa) is one of the most common cancers in men worldwide. Bi-parametric MRI (bp-MRI) and clinical variables are crucial for PCa identification and improving treatment decisions. However, this process is subjective to expert…

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The incorporation of physical information in machine learning frameworks is transforming medical image analysis (MIA). By integrating fundamental knowledge and governing physical laws, these models achieve enhanced robustness and…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Chayan Banerjee , Kien Nguyen , Olivier Salvado , Truyen Tran , Clinton Fookes

Artificial Intelligence (AI) has become commonplace to solve routine everyday tasks. Because of the exponential growth in medical imaging data volume and complexity, the workload on radiologists is steadily increasing. We project that the…

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

Background: Facial appearance offers a noninvasive window into health. We built FAHR-Face, a foundation model trained on >40 million facial images and fine-tuned it for two distinct tasks: biological age estimation (FAHR-FaceAge) and…

Our evolving understanding of the heterocellular cardiac environment demands innovative tools for its study. While murine models are lauded for their versatility and accessibility, they are constrained by scale; tools designed for larger…

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Prenatal diagnosis of Congenital Heart Diseases (CHDs) holds great potential for Artificial Intelligence (AI)-driven solutions. However, collecting high-quality diagnostic data remains difficult due to the rarity of these conditions,…

Artificial intelligence applied to retinal images offers significant potential for recognizing signs and symptoms of retinal conditions and expediting the diagnosis of eye diseases and systemic disorders. However, developing generalized…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Boa Jang , Youngbin Ahn , Eun Kyung Choe , Chang Ki Yoon , Hyuk Jin Choi , Young-Gon Kim

Recent advancements in AI and medical imaging offer transformative potential in emergency head CT interpretation for reducing assessment times and improving accuracy in the face of an increasing request of such scans and a global shortage…

Here we present a versatile foundation model that can perform a range of clinically-relevant image analysis tasks, including segmentation, landmark localisation, diagnosis, and prognostication. A multi-view convolution-transformer masked…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Yunguan Fu , Wenjia Bai , Weixi Yi , Charlotte Manisty , Anish N Bhuva , Thomas A Treibel , James C Moon , Matthew J Clarkson , Rhodri Huw Davies , Yipeng Hu

Noninvasive optical imaging modalities can probe patient's tissue in 3D and over time generate gigabytes of clinically relevant data per sample. There is a need for AI models to analyze this data and assist clinical workflow. The lack of…

AI-assisted imaging made substantial advances in tumor diagnosis and management. However, a major barrier to developing robust oncology foundation models is the scarcity of large-scale, high-quality annotated datasets, which are limited by…