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Foundation models (FMs) are rapidly reshaping medical imaging, shifting the field from narrowly trained, task-specific networks toward large, general-purpose models that can be adapted across modalities, anatomies, and clinical tasks. In…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Chuang Niu , Pengwei Wu , Bruno De Man , Ge Wang

Medical foundation models show promise to learn broadly generalizable features from large, diverse datasets. This could be the base for reliable cross-modality generalization and rapid adaptation to new, task-specific goals, with only a few…

Ultrasound (US) imaging exhibits substantial heterogeneity across anatomical structures and acquisition protocols, posing significant challenges to the development of generalizable analysis models. Most existing methods are task-specific,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Bo Deng , Yitong Tang , Jiake Li , Yuxin Huang , Li Wang , Yu Zhang , Yufei Zhan , Hua Lu , Xiaoshen Zhang , Jieyun Bai

Purpose: Most studies evaluating artificial intelligence (AI) models that detect abnormalities in neuroimaging are either tested on unrepresentative patient cohorts or are insufficiently well-validated, leading to poor generalisability to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-10 Siddharth Agarwal , David A. Wood , Mariusz Grzeda , Chandhini Suresh , Munaib Din , James Cole , Marc Modat , Thomas C Booth

A unified foundation model for medical time series -- pretrained on open access and ethics board-approved medical corpora -- offers the potential to reduce annotation burdens, minimize model customization, and enable robust transfer across…

Machine Learning · Computer Science 2025-12-17 Hao Li , Bowen Deng , Chang Xu , Zhiyuan Feng , Viktor Schlegel , Yu-Hao Huang , Yizheng Sun , Jingyuan Sun , Kailai Yang , Yiyao Yu , Jiang Bian

The development of radiology foundation models (RFMs) is hindered by a reliance on brute-force scaling. Existing approaches often directly translate methods for natural images, which prioritize scale over precision and hence lead to brittle…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yingtai Li , Shuai Ming , Mingyue Zhao , Haoran Lai , Rongsheng Wang , Rui Zhou , Rundong Wang , Yujia Li , Wei Wei , Shaohua Kevin Zhou

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Kang Yu , Dingyu Wang , Zimu Yuan , Nan Zhou , Jiajun Liu , Jiaxin Liu , Shanggui Liu , Yaoyan Zheng , Huishu Yuan , Di Huang , Dong Jiang

Optical tomography has emerged as a non-invasive imaging method, providing three-dimensional insights into subcellular structures and thereby enabling a deeper understanding of cellular functions, interactions, and processes. Conventional…

Medical Physics · Physics 2023-12-14 Jiawei Sun , Bin Yang , Nektarios Koukourakis , Jochen Guck , Juergen W. Czarske

As artificial intelligence (AI) becomes increasingly central to healthcare, the demand for explainable and trustworthy models is paramount. Current report generation systems for chest X-rays (CXR) often lack mechanisms for validating…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Sayeh Gholipour Picha , Dawood Al Chanti , Alice Caplier

This article discusses the opportunities, applications and future directions of large-scale pre-trained models, i.e., foundation models, for analyzing medical images. Medical foundation models have immense potential in solving a wide range…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Shaoting Zhang , Dimitris Metaxas

Fusion of multimodal healthcare data holds great promise to provide a holistic view of a patient's health, taking advantage of the complementarity of different modalities while leveraging their correlation. This paper proposes a simple and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Omnia Alwazzan , Ioannis Patras , Gregory Slabaugh

Computer-aided diagnosis systems hold great promise to aid radiologists and clinicians in radiological clinical practice and enhance diagnostic accuracy and efficiency. However, the conventional systems primarily focus on delivering…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Sheng Wang , Tianming Du , Katherine Fischer , Gregory E Tasian , Justin Ziemba , Joanie M Garratt , Hersh Sagreiya , Yong Fan

Coronary artery disease, the leading cause of cardiovascular mortality worldwide, can be assessed non-invasively by coronary computed tomography angiography (CCTA). Despite progress in automated CCTA analysis using deep learning, clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jinkui Hao , Gorkem Durak , Halil Ertugrul Aktas , Ulas Bagci , Bradley D. Allen , Nilay S. Shah , Bo Zhou

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Zhongying Deng , Cheng Tang , Ziyan Huang , Jiashi Lin , Ying Chen , Junzhi Ning , Chenglong Ma , Jiyao Liu , Wei Li , Yinghao Zhu , Shujian Gao , Yanyan Huang , Sibo Ju , Yanzhou Su , Pengcheng Chen , Wenhao Tang , Tianbin Li , Haoyu Wang , Yuanfeng Ji , Hui Sun , Shaobo Min , Liang Peng , Feilong Tang , Haochen Xue , Rulin Zhou , Chaoyang Zhang , Wenjie Li , Shaohao Rui , Weijie Ma , Xingyue Zhao , Yibin Wang , Kun Yuan , Zhaohui Lu , Shujun Wang , Jinjie Wei , Lihao Liu , Dingkang Yang , Lin Wang , Yulong Li , Haolin Yang , Yiqing Shen , Lequan Yu , Xiaowei Hu , Yun Gu , Yicheng Wu , Benyou Wang , Minghui Zhang , Angelica I. Aviles-Rivero , Qi Gao , Hongming Shan , Xiaoyu Ren , Fang Yan , Hongyu Zhou , Haodong Duan , Maosong Cao , Shanshan Wang , Bin Fu , Xiaomeng Li , Zhi Hou , Chunfeng Song , Lei Bai , Yuan Cheng , Yuandong Pu , Xiang Li , Wenhai Wang , Hao Chen , Jiaxin Zhuang , Songyang Zhang , Huiguang He , Mengzhang Li , Bohan Zhuang , Zhian Bai , Rongshan Yu , Liansheng Wang , Yukun Zhou , Xiaosong Wang , Xin Guo , Guanbin Li , Xiangru Lin , Dakai Jin , Mianxin Liu , Wenlong Zhang , Qi Qin , Conghui He , Yuqiang Li , Ye Luo , Nanqing Dong , Jie Xu , Wenqi Shao , Bo Zhang , Qiujuan Yan , Yihao Liu , Jun Ma , Zhi Lu , Yuewen Cao , Zongwei Zhou , Jianming Liang , Shixiang Tang , Qi Duan , Dongzhan Zhou , Chen Jiang , Yuyin Zhou , Yanwu Xu , Jiancheng Yang , Shaoting Zhang , Xiaohong Liu , Siqi Luo , Yi Xin , Chaoyu Liu , Haochen Wen , Xin Chen , Alejandro Lozano , Min Woo Sun , Yuhui Zhang , Yue Yao , Xiaoxiao Sun , Serena Yeung-Levy , Xia Li , Jing Ke , Chunhui Zhang , Zongyuan Ge , Ming Hu , Jin Ye , Zhifeng Li , Yirong Chen , Yu Qiao , Junjun He

Artificial intelligence (AI) has shown promise in detecting and characterizing musculoskeletal diseases from radiographs. However, most existing models remain task-specific, annotation-dependent, and limited in generalizability across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Shinn Kim , Soobin Lee , Kyoungseob Shin , Han-Soo Kim , Yongsung Kim , Minsu Kim , Juhong Nam , Somang Ko , Daeheon Kwon , Wook Huh , Ilkyu Han , Sunghoon Kwon

Despite recent advances in cancer treatments that prolong patients' lives, treatment-induced cardiotoxicity remains one severe side effect. The clinical decision-making of cardiotoxicity is challenging, as non-clinical symptoms can be…

Human-Computer Interaction · Computer Science 2025-03-04 Siyi Wu , Weidan Cao , Shihan Fu , Bingsheng Yao , Ziqi Yang , Changchang Yin , Varun Mishra , Daniel Addison , Ping Zhang , Dakuo Wang

Foundation models have recently achieved impressive success in computational pathology, demonstrating strong generalization across diverse histopathology tasks. However, existing models overlook the heterogeneous and non-uniform…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Di Zhang , Zhangpeng Gong , Xiaobo Pang , Jiashuai Liu , Junbo Lu , Hao Cui , Jiusong Ge , Zhi Zeng , Kai Yi , Yinghua Li , Si Liu , Tingsong Yu , Haoran Wang , Mireia Crispin-Ortuzar , Weimiao Yu , Chen Li , Zeyu Gao

Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 José Morano , Botond Fazekas , Emese Sükei , Ronald Fecso , Taha Emre , Markus Gumpinger , Georg Faustmann , Marzieh Oghbaie , Ursula Schmidt-Erfurth , Hrvoje Bogunović

The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Jie Liu , Yixiao Zhang , Kang Wang , Mehmet Can Yavuz , Xiaoxi Chen , Yixuan Yuan , Haoliang Li , Yang Yang , Alan Yuille , Yucheng Tang , Zongwei Zhou

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka