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Kinetic modeling of microbial growth is essential for the design, optimization, and scale-up of industrial bioprocesses. Classical empirical models often lack biologically interpretable parameters or fail to capture complex multiphasic…

Quantitative Methods · Quantitative Biology 2026-04-10 Gustavo Mockaitis

This investigation presents novel adaptive control algorithms specifically designed to address and mitigate thermoacoustic instabilities. Two control strategies are available to alleviate this issue: active and passive. Active control…

Optimization and Control · Mathematics 2024-07-02 Bayu Dharmaputra , Pit Reckinger , Bruno Schuermans , Nicolas Noiray

This work deals with the design optimization of electrical machines under the consideration of manufacturing uncertainties. In order to efficiently quantify the uncertainty, blackbox machine learning methods are employed. A multi-objective…

Computational Engineering, Finance, and Science · Computer Science 2023-11-27 Morten Huber , Mona Fuhrländer , Sebastian Schöps

The mechanical performance of plant fibres is linked to the presence of crystalline elements dispersed within an amorphous cohesive matrix. The more the crystalline reinforcement is aligned with the fibre axis, the better the mechanical…

Classical Physics · Physics 2025-12-16 Moisy Amélie , Voisin Hugo , Davy Joëlle , Cathala Bernard , Guessasma Sofiane

Multigrid methods are asymptotically optimal algorithms ideal for large-scale simulations. But, they require making numerous algorithmic choices that significantly influence their efficiency. Unlike recent approaches that learn optimal…

Computational Engineering, Finance, and Science · Computer Science 2024-12-12 Dinesh Parthasarathy , Tommaso Bevilacqua , Martin Lanser , Axel Klawonn , Harald Köstler

Stochastic fluctuations of molecular abundances are a ubiquitous feature of cellular processes and lead to significant cell-to-cell variability. Recent theoretical work established lower bounds for stochastic fluctuations in cells for broad…

Molecular Networks · Quantitative Biology 2025-05-06 Brayden Kell , Andreas Hilfinger

We demonstrate that the permeability of the cell wall of microalga $\textit{C. reinhardtii}$ can be enhanced in controlled microstreaming flow conditions using single bubbles adherent to a wall and driven by ultrasound near their resonance…

Quantitative Methods · Quantitative Biology 2021-12-20 Angelo Pommella , Irina Harun , Klaus Hellgardt , Valeria Garbin

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

Populations and Evolution · Quantitative Biology 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

We study how simple eukaryotic organisms make decisions in response to competing stimuli in the context of phototaxis by the unicellular alga $Chlamydomonas~reinhardtii$. While negatively phototactic cells swim directly away from a…

The increasing interconnection of power systems through AC and DC links enables energy storage units to access multiple electricity markets yet most existing arbitrage models remain limited to singlemarket participation This gap restricts…

Systems and Control · Electrical Eng. & Systems 2026-04-09 Md Umar Hashmi , Harsha Nagarajan , Dirk Van Hertem1

This article presents new hexagonal and pentagonal PEM fuel cell models. The models have been optimized after achieving improved cell performance. The input parameters of the multi-objective optimization algorithm were pressure and…

Neural and Evolutionary Computing · Computer Science 2023-10-18 Ali Jabbary , Nader Pourmahmoud , Mir Ali Asghar Abdollahi , Marc A. Rosen

In order to deploy machine learning in a real-world self-driving laboratory where data acquisition is costly and there are multiple competing design criteria, systems need to be able to intelligently sample while balancing performance…

Machine Learning · Computer Science 2023-04-18 Tyler H. Chang , Jakob R. Elias , Stefan M. Wild , Santanu Chaudhuri , Joseph A. Libera

While the forward and backward modeling of the process-structure-property chain has received a lot of attention from the materials community, fewer efforts have taken into consideration uncertainties. Those arise from a multitude of sources…

Machine Learning · Statistics 2021-08-06 Maximilian Rixner , Phaedon-Stelios Koutsourelakis

Phototaxis is one of the most fundamental stimulus-response behaviors in biology wherein motile micro-organisms sense light gradients to swim towards the light source. Apart from single cell survival and growth, it plays a major role at the…

Soft Condensed Matter · Physics 2020-01-08 Sujeet Kumar Choudhary , Aparna Baskaran , Prerna Sharma

This paper presents a methodological framework for training, self-optimising, and self-organising surrogate models to approximate and speed up multiobjective optimisation of technical systems based on multiphysics simulations. At the hand…

Machine Learning · Computer Science 2024-04-04 Diego Botache , Jens Decke , Winfried Ripken , Abhinay Dornipati , Franz Götz-Hahn , Mohamed Ayeb , Bernhard Sick

Metabolism and evolution are closely connected: if a mutation incurs extra energetic costs for an organism, there is a baseline selective disadvantage that may or may not be compensated for by other adaptive effects. A long-standing, but to…

Populations and Evolution · Quantitative Biology 2019-06-19 Efe Ilker , Michael Hinczewski

Most approaches for designing self-assembled materials focus on the thermodynamic stability of a target structure or crystal polymorph. Yet in practice, the outcome of a self-assembly process is often controlled by kinetic pathways. Here we…

Soft Condensed Matter · Physics 2025-05-08 Sambarta Chatterjee , William M. Jacobs

We introduce a model of the growth of a single microorganism in a self-cycling fermentor in which an arbitrary number of resources are limiting, and impulses are triggered when the concentration of one specific substrate reaches a…

Dynamical Systems · Mathematics 2020-04-28 Tyler Meadows , Gail S. K. Wolkowicz

Increasingly volatile electricity prices make simultaneous scheduling optimization desirable for production processes and their energy systems. Simultaneous scheduling needs to account for both process dynamics and binary on/off-decisions…

Optimization and Control · Mathematics 2022-07-28 Florian Joseph Baader , André Bardow , Manuel Dahmen

In a post-prognostics decision context, this paper addresses the problem of maximizing the useful life of a platform composed of several parallel machines under service constraint. Application on multi-stack fuel cell systems is considered.…

Computational Engineering, Finance, and Science · Computer Science 2017-10-25 Stephane Chretien , Nathalie Herr , Jean-Marc Nicod , Christophe Varnier