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State-of-the-art aeronautic Low Pressure gas Turbines (LPTs) are already characterized by high quality standards, thus they offer very narrow margins of improvement. Typical design process starts with a Concept Design (CD) phase, defined…

Optimization and Control · Mathematics 2014-02-04 Francesco Bertini , Lorenzo Dal Mas , Luca Vassio , Enrico Ampellio

We derive the explicit solutions to singular stochastic control problems of the monotone follower type with (a) an expected discounted criterion, (b) an expected ergodic criterion and (c) a pathwise ergodic criterion. These problems have…

Optimization and Control · Mathematics 2025-02-05 Gechun Liang , Zhesheng Liu , Mihail Zervos

We introduce a new and efficient numerical method for multicriterion optimal control and single criterion optimal control under integral constraints. The approach is based on extending the state space to include information on a "budget"…

Optimization and Control · Mathematics 2016-01-06 Ajeet Kumar , Alexander Vladimirsky

Guaranteed maximization of financial returns from economic structures is only possible if all of its systems are focused on selecting target operations with maximum efficiency. Is it possible? Any system is created to enhance the value of…

Optimization and Control · Mathematics 2015-10-15 Igor Lutsenko

Multi-task learning uses auxiliary data or knowledge from relevant tasks to facilitate the learning in a new task. Multi-task optimization applies multi-task learning to optimization to study how to effectively and efficiently tackle…

Neural and Evolutionary Computing · Computer Science 2019-09-17 Dongrui Wu , Xianfeng Tan

Hydrogen fuel cells are a key technology in the transition toward carbon-neutral energy systems, offering clean power with water as the only byproduct. Microfluidic fuel cells, which operate at the microliter scale, are an emerging variant…

Computational Engineering, Finance, and Science · Computer Science 2026-03-31 Michel Takken , Robert Wille

The system comprises of three interconnected power system networks based on thermal, wind and hydro power generation. The load variation in any one of the network results in frequency deviation in all the connected systems.The PI…

Systems and Control · Computer Science 2017-01-30 Naresh Kumari , Nitin Malik , A. N. Jha , Gaddam Mallesham

Microfiltration technology is a widely used engineering strategy for fresh water production and water treatment. The major concern in many applications is the formation of a biological fouling layer leading to increased hydraulic resistance…

Biological Physics · Physics 2021-04-12 V. Luongo , M. R. Mattei , L. Frunzo , B. D'Acunto , K. Gupta , S. Chellam , N. G. Cogan

We consider the chemostat model with the substrate concentration as the single measurement. We propose a control strategy that drives the system at a steady state maximizing the gas production without the knowledge of the specific growth…

Optimization and Control · Mathematics 2013-05-14 Alain Rapaport , Jan Sieber , Serafim Rodrigues , Mathieu Desroches

Bioprocesses are central to modern biotechnology, enabling sustainable production in pharmaceuticals, specialty chemicals, cosmetics, and food. However, developing high-performing processes is costly and complex, requiring iterative,…

Quantitative Methods · Quantitative Biology 2025-08-18 Adrian Martens , Mathias Neufang , Alessandro Butté , Moritz von Stosch , Antonio del Rio Chanona , Laura Marie Helleckes

In this article we propose an inverse analysis algorithm to find the best fit of multiple material parameters in different coupled multi-physics biofilm models. We use a nonlinear continuum mechanical approach to model biofilm deformation…

Computational Engineering, Finance, and Science · Computer Science 2022-12-26 Harald Willmann , Wolfgang A. Wall

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian

Organic molecular crystals are appealing for next-generation optoelectronic applications, most notably due to their multiexciton generation process that can increase the efficiency of photovoltaic devices. However, a general understanding…

Materials Science · Physics 2021-11-01 Aaron R. Altman , Sivan Refaely-Abramson , Felipe H. da Jornada

Optimization-based models have been used to predict cellular behavior for over 25 years. The constraints in these models are derived from genome annotations, measured macro-molecular composition of cells, and by measuring the cell's growth…

Quantitative Methods · Quantitative Biology 2019-05-21 Laurence Yang , Michael A. Saunders , Jean-Christophe Lachance , Bernhard O. Palsson , José Bento

Continuous-time generative models have achieved remarkable success in image restoration and synthesis. However, controlling the composition of multiple pre-trained models remains an open challenge. Current approaches largely treat…

Machine Learning · Computer Science 2026-05-20 Riccardo Barbano , Alexander Denker , Zeljko Kereta , Runchang Li , Francisco Vargas

In this paper, the stability analysis of an anaerobic digestion process is presented. The analysis is performed using a simplified mathematical model, which includes explicit temperature and pH dependence on kinetic growth rates. A detailed…

Populations and Evolution · Quantitative Biology 2017-06-08 Angélica M. Alzate Ibañez , Carlos Ocampo-Martinez , Carlos A. Cardona Alzate , Víctor M. Trejos M

The industrial implementation of biofuel production from lignocellulosic biomass faces a number of economic obstacles. One of these is the cost of enzymes, typically used for cellulose hydrolysis. Nature provides some hints towards the…

Soft Condensed Matter · Physics 2021-11-02 O. Paiuk , A. Zaichenko , N. Mitina , J. Ilnytskyi , T. Patsahan , S. Minko , Kh. Harhay , V. Garamus , K. Volianiuk

We study the optimization of the expected long-term reward in finite partially observable Markov decision processes over the set of stationary stochastic policies. In the case of deterministic observations, also known as state aggregation,…

Optimization and Control · Mathematics 2022-11-18 Mareike Dressler , Marina Garrote-López , Guido Montúfar , Johannes Müller , Kemal Rose

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

Biological Physics · Physics 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

Multifidelity and multioutput optimisation algorithms are of active interest in many areas of computational design as they allow cheaper computational proxies to be used intelligently to aid experimental searches for high-performing…

Machine Learning · Statistics 2022-08-29 Clyde Fare , Peter Fenner , Edward O. Pyzer-Knapp