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Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…

We propose to fuse two currently separate research lines on novel therapies for stroke rehabilitation: brain-computer interface (BCI) training and transcranial electrical stimulation (TES). Specifically, we show that BCI technology can be…

Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental…

Neurons and Cognition · Quantitative Biology 2020-12-30 Jose Gomez-Tames , Ilkka Laakso , Akimasa Hirata

Electromagnetic stimulation of the human brain is a key tool for the neurophysiological characterization and diagnosis of several neurological disorders. Transcranial magnetic stimulation (TMS) is one procedure that is commonly used…

Machine Learning · Computer Science 2020-02-04 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

The main objective of the electrical stimulation of the brain is to generate action potentials from the application of electromagnetic fields. Among the available techniques, transcranial electrical stimulation (TES) represents a popular…

Medical Physics · Physics 2015-11-09 Carlos G. Tarazona , Carlos E. Guerra , Laura Chávez , Sebastián Andrade

Background and Objective: Transcranial temporal interference stimulation (tTIS) is a promising non-invasive brain stimulation technique in which interference between electrical current fields extends the possibilities of electrical brain…

Numerical Analysis · Mathematics 2026-02-05 Santtu Söderholm , Maryam Samavaki , Sampsa Pursiainen

For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…

Neurons and Cognition · Quantitative Biology 2025-12-17 Pierre Vassiliadis , Elena Beanato , Maximilian J. Wessel , Friedhelm C. Hummel

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

Neurons and Cognition · Quantitative Biology 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

In this article, we design a novel Transcranial Electrical Stimulator for medical applications, which is very cheap and can produce the desired signals very accurately. Our fabricated stimulator generates all current signals related to…

Signal Processing · Electrical Eng. & Systems 2020-09-10 HoseinAli Jafari , Mohammad Bagher Heydari , Niloofar Jafari , Hamid Mirhosseini

Electro-stimulation or modulation of deep brain regions is commonly used in clinical procedures for the treatment of several nervous system disorders. In particular, transcranial direct current stimulation (tDCS) is widely used as an…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Personalized treatments are gaining momentum across all fields of medicine. Precision medicine can be applied to neuromodulatory techniques, where focused brain stimulation treatments such as repetitive transcranial magnetic stimulation…

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

This study evaluated transcranial temporal interference stimulation (tTIS) for focal targeting of the insula and hippocampus, which are clinically relevant yet anatomically difficult to stimulate. Individualized and group-level electrode…

Medical Physics · Physics 2025-10-28 Taiga Inoue , Naofumi Otsuru , Akimasa Hirata

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

Medical Physics · Physics 2023-12-27 Max Koehler , Stefan Goetz

Introduction: Rehabilitation after a neurological impairment can be supported by functional electrical stimulation (FES). However, FES is limited by early muscle fatigue, slowing down the recovery progress. The use of optimal control to…

Medical Physics · Physics 2025-08-06 Kevin Co , Mickaël Begon , François Bailly , Florent Moissenet

Transcranial direct current stimulation is a non-invasive brain stimulation technique which modifies neural excitability by providing weak currents through scalp electrodes. The aim of this study is to introduce and analyze a novel…

Optimization and Control · Mathematics 2016-09-27 Sven Wagner , Martin Burger , Carsten H. Wolters

Concurrency of transcranial magnetic stimulation with electroencephalography (TMS-EEG) technique is a powerful and challenging methodology for basic research and clinical applications. Aspects considered in experiments for effective TMS-EEG…

Neurons and Cognition · Quantitative Biology 2024-03-18 Hua Cheng

Background: Transcranial magnetic stimulation (TMS) is a powerful tool to investigate neurophysiology of the human brain and treat brain disorders. Traditionally, therapeutic TMS has been applied in a one-size-fits-all approach,…

This paper explores advanced electrode modeling in the context of separate and parallel transcranial electrical stimulation (tES) and electroencephalography (EEG) measurements. We focus on boundary condition based approaches that do not…

Medical Physics · Physics 2016-08-22 Britte Agsten , Sven Wagner , Sampsa Pursiainen , Carsten H. Wolters

Concurrent transcranial magnetic stimulation (TMS) and electroencephalography (EEG), or TMS-EEG, holds the potential to broaden the clinical applications of TMS beyond its traditional role in evaluating the cortico-spinal tract and motor…

Neurons and Cognition · Quantitative Biology 2025-02-04 Giacomo Bertazzoli , Carlo Miniussi , Petro Julkunen , Marta Bortoletto
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