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Intracranial language brain-computer interfaces (BCIs) are a promising route for restoring communication in people with severe motor and speech impairments, but clinical translation remains limited by fragmented evidence and unresolved…

Neurons and Cognition · Quantitative Biology 2026-03-17 Dongyi He , Wai Ting Siok , Nizhuan Wang

This numerical simulation study investigates solving the L1-norm fitted and regularized (L1-L1) linear programming (LP) problem to find a well-localized volumetric current density in transcranial electrical stimulation (tES), where a…

Optimization and Control · Mathematics 2022-09-26 F. Galaz Prieto , M. Samavaki , S. Pursiainen

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a multitude of neurological and neuropsychiatric disorders. At the single-patient level, however, symptoms may sometimes persist despite "optimal"…

Identifying what aspects of brain activity are responsible for conscious perception remains one of the most challenging problems in science. While progress has been made through psychophysical studies employing EEG and fMRI, research would…

Neurons and Cognition · Quantitative Biology 2025-07-14 Daniel K. Freeman , Brian Odegaard , Seung-Schik Yoo , Matthias Michel

Recent advances in biosensors technology and mobile electroencephalographic (EEG) interfaces have opened new application fields for cognitive monitoring. A computable biomarker for the assessment of spontaneous aesthetic brain responses…

Neurons and Cognition · Quantitative Biology 2016-09-26 Dimitrios A. Adamos , Stavros I. Dimitriadis , Nikolaos A. Laskaris

Electrical brain stimulation is currently being investigated as a therapy for neurological disease. However, opportunities to optimize such therapies are challenged by the fact that the beneficial impact of focal stimulation on both…

Neurostimulation using weak electric fields has generated excitement in recent years due to its potential as a medical intervention. However, study of this stimulation modality has been hampered by inconsistent results and large variability…

Neurons and Cognition · Quantitative Biology 2020-01-29 Frances Hutchings , Christopher Thornton , Chencheng Zhang , Yujiang Wang , Marcus Kaiser

The development of personalized human head models from medical images has become an important topic in the electromagnetic dosimetry field, including the optimization of electrostimulation, safety assessments, etc. Human head models are…

Image and Video Processing · Electrical Eng. & Systems 2020-02-24 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Accurate electromagnetic modeling of the head of a subject is of main interest in the fields of source reconstruction and brain stimulation. Those processes rely heavily on the quality of the model and, even though the geometry of the…

Medical Physics · Physics 2022-02-15 Martin Grignard , Christophe Geuzaine , Christophe Phillips

The present literature about possible mechanisms behind the effectivity of noninvasive electromagnetic stimulation in major depressive disorder (MDD) is not very rich. Despite extensive research in applications for clinical practice, the…

Neurons and Cognition · Quantitative Biology 2019-12-19 Milena Cukic

Noninvasive brain stimulation (NIBS) by quasistatic electromagnetic means is presently comprised of two methods: Magnetic induction methods (Transcranial magnetic perturbation or TMP) and electrical contact methods (Transcranial electric…

Medical Physics · Physics 2020-06-11 D. J. Sheltraw , B. Inglis , L. Labruna , R. Ivry

Excitable tissue is fundamental to brain function, yet its study is complicated by extreme morphological complexity and the physiological processes governing its dynamics. Consequently, detailed computational modeling of this tissue…

Purpose: This study investigates the feasibility of transcutaneous interferential spinal cord stimulation (tISCS), a novel non-invasive neuromodulation method, using temporal interference to enhance focality and comfort in spinal cord…

Neurological and Physiological Disorders that impact emotional regulation each have their own unique characteristics which are important to understand in order to create a generalized solution to all of them. The purpose of this experiment…

Human-Computer Interaction · Computer Science 2024-11-25 Vedant Mehta

Acquisition of fine motor skills is a time-consuming process as it requires frequent repetitions. Transcranial electrical stimulation is a promising means of enhancing simple motor skill development via neuromodulatory mechanisms. Here, we…

Transcranial photobiomodulation (tPBM) therapy is an emerging, non-invasive neuromodulation technique that has demonstrated considerable potential in the field of neuropsychiatric disorders. Several studies have found that pulsed wave (PW)…

Neurons and Cognition · Quantitative Biology 2025-12-02 Jiangshan He , Hui Xie , Yuqiang Yang , Chunli Jia , Dan Liang , Lianghua Zhang , Xiaoyu Wang , Tianyi Luo , Zexiao Dong , Huiting Yang , Zhen Yuan , Mingzhe Jiang , Xueli Chen

Transcranial ultrasonic stimulation (TUS) has the potential to usher in a new era for human neuroscience by allowing spatially precise and high-resolution non-invasive targeting of both deep and superficial brain regions. Currently,…

Transcranial direct current stimulation (tDCS) is known to have a modulatory effect on neural tissue and that it is polarity specific. It is also shown that tDCS demonstrated the lasting effect in therapeutic applications. The main aim of…

Neurons and Cognition · Quantitative Biology 2018-12-05 Milena Cukic , Miodrag Stokic , Slavoljub Radenkovic , Milos Ljubisavljevic , Dragoljub Donald Pokrajac

Sleep is crucial for memory consolidation, underpinning effective learning. Targeted memory reactivation (TMR) can strengthen neural representations by re-engaging learning circuits during sleep. However, TMR protocols overlook individual…

Human-Computer Interaction · Computer Science 2025-11-20 Gi-Hwan Shin , Young-Seok Kweon , Seungwon Oh , Seong-Whan Lee

Emotion recognition based on Electroencephalography (EEG) has gained significant attention and diversified development in fields such as neural signal processing and affective computing. However, the unique brain anatomy of individuals…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Yihang Dong , Xuhang Chen , Yanyan Shen , Michael Kwok-Po Ng , Tao Qian , Shuqiang Wang