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Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

Computation and Language · Computer Science 2026-05-28 Yinghao Zhu , Lei Gu , Zixiang Wang , Haoran Sang , Dehao Sui , Wen Tang , Lan Mi , Yasha Wang , Junyi Gao , Liang Yao , Tianfan Fu , Ewen Harrison , Lequan Yu , Liantao Ma

Multi-agent systems (MAS) have emerged as a promising approach for enhancing the reasoning capabilities of large language models in complex problem-solving; however, current MAS frameworks suffer from poor flexibility and scalability with…

Multiagent Systems · Computer Science 2025-06-02 Heng Zhou , Hejia Geng , Xiangyuan Xue , Li Kang , Yiran Qin , Zhiyong Wang , Zhenfei Yin , Lei Bai

Building effective clinical decision support systems requires the synthesis of complex heterogeneous multimodal data. Such modalities include temporal electronic health records data, medical images, radiology reports, and clinical notes.…

Artificial Intelligence · Computer Science 2026-05-12 Baraa Al Jorf , Farah E. Shamout

This study investigates large language model (LLM) -based multi-agent systems (MASs) as a promising approach to inventory management, which is a key component of supply chain management. Although these systems have gained considerable…

Multiagent Systems · Computer Science 2026-02-06 Konosuke Yoshizato , Kazuma Shimizu , Ryota Higa , Takanobu Otsuka

Multimodal clinical reasoning in the field of gastrointestinal (GI) oncology necessitates the integrated interpretation of endoscopic imagery, radiological data, and biochemical markers. Despite the evident potential exhibited by Multimodal…

Inpatient pathways demand complex clinical decision-making based on comprehensive patient information, posing critical challenges for clinicians. Despite advancements in large language models (LLMs) in medical applications, limited research…

Artificial Intelligence · Computer Science 2025-03-18 Zhen Chen , Zhihao Peng , Xusheng Liang , Cheng Wang , Peigan Liang , Linsheng Zeng , Minjie Ju , Yixuan Yuan

Large Language Models (LLMs) have demonstrated remarkable capabilities in various reasoning and generation tasks. However, their proficiency in complex causal reasoning, discovery, and estimation remains an area of active development, often…

Artificial Intelligence · Computer Science 2025-09-03 Adib Bazgir , Amir Habibdoust , Yuwen Zhang , Xing Song

The rapid adoption of large language models (LLMs) in digital health has been driven by a "scaling-first" philosophy, i.e., the assumption that clinical intelligence increases with model size and data. However, real-world clinical needs…

Artificial Intelligence · Computer Science 2026-05-29 Yuqiao Meng , Luoxi Tang , Dazheng Zhang , Rafael Brens , Elvys J. Romero , Nancy Guo , Safa Elkefi , Zhaohan Xi

Rare disease diagnosis is inherently challenging due to heterogeneous symptoms, limited clinical familiarity, and fragmented evidence across specialties. Recent large language model (LLM)-based agentic systems have shown promise by…

Human-Computer Interaction · Computer Science 2026-03-31 Peng Kuai , Yukun Yang , Shaolun Ruan , Junchi Xu , Yanjie Zhang , Lin Zhang , Min Zhu , Rui Sheng

Large language model (LLM)-based multi-agent systems have demonstrated impressive capabilities in handling complex tasks. However, the complexity of agentic behaviors makes these systems difficult to understand. When failures occur,…

Human-Computer Interaction · Computer Science 2026-02-06 Rui Sheng , Yukun Yang , Chuhan Shi , Yanna Lin , Zixin Chen , Huamin Qu , Furui Cheng

Clinical dialogue represents a complex duality requiring both the empathetic fluency of natural conversation and the rigorous precision of evidence-based medicine. While Large Language Models possess unprecedented linguistic capabilities,…

Other Quantitative Biology · Quantitative Biology 2025-12-02 Xiaoquan Zhi , Hongke Zhao , Likang Wu , Chuang Zhao , Hengshu Zhu

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis…

Artificial Intelligence · Computer Science 2025-03-24 Sihan Wang , Suiyang Jiang , Yibo Gao , Boming Wang , Shangqi Gao , Xiahai Zhuang

Early-stage engineering design involves complex, iterative reasoning, yet existing large language model (LLM) workflows struggle to maintain task continuity and generate executable models. We evaluate whether a structured multi-agent system…

Artificial Intelligence · Computer Science 2025-11-04 Soheyl Massoudi , Mark Fuge

Large language models applied to clinical prediction exhibit case-level heterogeneity: simple cases yield consistent outputs, while complex cases produce divergent predictions under minor prompt changes. Existing single-agent strategies…

Artificial Intelligence · Computer Science 2026-04-02 Yuxing Lu , Yushuhong Lin , Jason Zhang

Large Language Models (LLMs) are increasingly deployed as reasoning systems, where reasoning paradigms - such as Chain-of-Thought (CoT) and multi-agent systems (MAS) - play a critical role, yet their relative effectiveness and cost-accuracy…

Machine Learning · Computer Science 2026-01-21 Yapeng Li , Jiakuo Yu , Zhixin Liu , Xinnan Liu , Jing Yu , Songze Li , Tonghua Su

Recent advancements in Large Language Models (LLMs) and autonomous agents have demonstrated remarkable capabilities across various domains. However, standalone agents frequently encounter limitations when handling complex tasks that demand…

Computation and Language · Computer Science 2025-05-29 Rennai Qiu , Chen Qian , Ran Li , Yufan Dang , Weize Chen , Cheng Yang , Yingli Zhang , Ye Tian , Xuantang Xiong , Lei Han , Zhiyuan Liu , Maosong Sun

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

Multimodal large language models (MLLMs) have shown remarkable capabilities in cross-modal understanding and reasoning, offering new opportunities for intelligent assistive systems, yet existing systems still struggle with risk-aware…

Robotics · Computer Science 2026-04-08 Renjun Gao

Clinical data-driven research requires clinical expertise, programming skills, access to patient data, and extensive documentation, creating barriers and slowing the pace for clinicians and external researchers. To address this, we…

Computation and Language · Computer Science 2026-04-22 Taehun Kim , Hyeryun Park , Hyeonhoon Lee , Yushin Lee , Kyungsang Kim , Hyung-Chul Lee

Collaborative reasoning with multiple agents offers the potential for more robust and diverse problem-solving. However, existing approaches often suffer from homogeneous agent behaviors and lack of reflective and rethinking capabilities. We…

Artificial Intelligence · Computer Science 2025-11-13 Jian Zhang , Zhiyuan Wang , Zhangqi Wang , Fangzhi Xu , Qika Lin , Lingling Zhang , Rui Mao , Erik Cambria , Jun Liu