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Due to the limited capabilities of a single bio-nanomachine, complicated tasks can be performed only with the co-operation of multiple bio-nanomachines. In this work, we consider a diffusion-based molecular communication system with a…

Information Theory · Computer Science 2020-05-20 Nithin V. Sabu , Abhishek K. Gupta

The aim of this work is to develop dual-functional scaffolds for bone tissue regeneration and local antibiotic delivery applications. In this respect, bioresorbable bredigite (Ca7MgSi4O16) porous scaffolds were fabricated by a foam replica…

Biological Physics · Physics 2026-04-21 A. Jadidi , E. Salahinejad , E. Sharifi , L. Tayebi

Nitinol (NiTi shape-memory alloy) is an interesting candidate in various medical applications like dental, orthopedic, and cardiovascular devices, owing to its unique mechanical behaviors and proper biocompatibility. The aim of this work is…

Biological Physics · Physics 2026-01-29 M. Moradi , E. Salahinejad , E. Sharifi , L. Tayebi

In this paper, we design a drug release mechanism for dynamic time division multiple access (TDMA)-based molecular communication via diffusion (MCvD). In the proposed scheme, the communication frame is divided into several time slots over…

Signal Processing · Electrical Eng. & Systems 2019-09-02 Hamid Khoshfekr Rudsari , Nader Mokari , Mohammad Reza Javan , Eduard A. Jorswieck , Mahdi Orooji

Recent remarkable advancements in geometric deep generative models, coupled with accumulated structural data, enable structure-based drug design (SBDD) using only target protein information. However, existing models often struggle to…

Biomolecules · Quantitative Biology 2026-03-09 Joongwon Lee , Wonho Zhung , Jisu Seo , Woo Youn Kim

Cotton gauze bandages (CGB) are one of the most widely used wound dressing materials. These bandages are placed over a wound site to keep it clean and facilitate the healing process. However, it is used along with antibacterial agents…

Medical Physics · Physics 2021-05-24 Rohit Parkale , Priyanka Pulugu , Prasoon Kumar

The design of antibacterial-releasing coatings or wrapping materials with controlled drug release capability is a promising strategy to minimise risks of infection and medical device failure in vivo. Collagen fibres have been employed as…

Biomolecules · Quantitative Biology 2021-01-06 M. Tarik Arafat , Giuseppe Tronci , David J. Wood , Stephen J. Russell

Recently, Molecular Communication (MC) has been recognized as an enabling technology for nanonetworks where MC is envisioned to enable nanorobots to achieve sophisticated and complex tasks in the human body for promising medical…

Systems and Control · Electrical Eng. & Systems 2020-03-05 AbdulAziz Al-Helali , Ben Liang , Nidal Nasser

The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…

Fluid Dynamics · Physics 2024-01-23 V. Puthumana , P. G. Chen , M. Leonetti , R. Lasserre , M. Jaeger

Genetic engineering of cells has a range of applications in treating incurable diseases. Plasmid DNA is a popular choice of nucleic acid for cell engineering due to its low cost and stability. However, plasmid DNA must survive the…

Biological Physics · Physics 2025-10-06 Leyla Akh , Apresio K. Fajrial , Benjamin Seelbinder , Xin Xu , Wei Tan , Jill Slansky , Corey P. Neu , Xiaoyun Ding

Simple and easy to implement testbeds are needed to further advance molecular communication research. To this end, this paper presents an in-vessel molecular communication testbed using magnetic nanoparticles dispersed in an aqueous…

Biomolecular condensates form by phase separation of biological polymers and have important functions in the cell $-$ functions that are inherently connected to their physical properties. A remarkable aspect of such condensates is that…

Molecular carriers represent an increasingly common strategy in the field of nanopore sensing to use secondary molecules to selectively report on the presence of target analytes in solution, allowing for sensitive assays of otherwise…

Biomolecules · Quantitative Biology 2023-05-10 Zachary Roelen , Vincent Tabard-Cossa

Spherical multi-layered structures are prevalent in numerous biological systems and engineered applications, including tumor spheroids, layered tissues, and multi-shell nanoparticles for targeted drug delivery. Despite their widespread…

Information Theory · Computer Science 2025-03-19 Mitra Rezaei , Michael Chappell , Adam Noel

Nanoscale biosystems are widely used in numerous medical applications. The approaches for structure and function of the nanomachines that are available in the cell (natural nanomachines) are discussed. Molecular simulation studies have been…

Biological Physics · Physics 2016-09-08 Babu A Manjasetty , T. R. Gopalakrishnan Nair , Y. S. Ramaswamy

Pulmonary drug delivery systems rely on inhalation of drug-laden aerosols produced from aerosol generators such as inhalers, nebulizers etc. On deposition, the drug molecules diffuse in the mucus layer and are also subjected to mucociliary…

Tissues and Organs · Quantitative Biology 2022-01-14 Aranyak Chakravarty , Mahesh V. Panchagnula , Alladi Mohan , Neelesh A. Patankar

Recent studies have proposed that the diffusion of messenger molecules, such as monoamines, can mediate the plastic adaptation of synapses in supervised learning of neural networks. Based on these findings we developed a model for neural…

Neurons and Cognition · Quantitative Biology 2017-09-21 Damian L. Berger , Lucilla de Arcangelis , Hans J. Herrmann

All materials enter or exit the cell nucleus through nuclear pore complexes (NPCs), efficient transport devices that combine high selectivity and throughput. A central feature of this transport is the binding of cargo-carrying soluble…

Cell Behavior · Quantitative Biology 2015-06-26 A. Zilman , S. DiTalia , B. T. Chait , M. P Rout , M. O. Magnasco

Polymer nanocomposites (PNCs) offer a broad range of thermophysical properties that are linked to their compositions. However, it is challenging to establish a universal composition-property relation of PNCs due to their enormous…

Materials Science · Physics 2022-08-25 Kumar Ayush , Abhishek Seth , Tarak K Patra

Peptide nucleic acids (PNAs) are artificial nucleic acids with a peptide backbone instead of sugar phosphate backbone of DNA or RNA. Their resistance to degradation, selectivity and greater binding affinity in comparison to usual nucleic…

Biomolecules · Quantitative Biology 2019-10-18 Reyhane Alidousti , Mostafa Shakhsi-Niaee
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