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Recent studies have suggested that the Nuclear Pore Complex (NPC) plays a significant role in mechanotransduction. When a force is exerted, the NPC's diameter widens, leading to an increased molecular flux into the nucleus. In this study,…

Biological Physics · Physics 2025-04-09 Atsushi Matsuda , Mohammad R. K. Mofrad

Molecular communication (MC) enables information exchange at the nano- and microscale, with applications in areas like drug delivery and health monitoring. These event-driven scenarios often require alternatives to traditional transmission.…

Information Theory · Computer Science 2025-06-18 Yaning Zhao , Luca Miszewski , Christian Deppe , Massimiliano Pierobon

Design and characterisation of capsules is not an easy task owing to the multiple involved preparation factors and parameters. Here, a novel method to characterise capsule membrane permeability to solute molecules by an inverse approach is…

Medical Physics · Physics 2021-11-03 Clément Bielinski , Badr Kaoui

Cellulose, as a naturally abundant and biocompatible material, is still gaining interest due to its high potential for functionalization. This makes cellulose a promising candidate for replacing plastics. Understanding how cellulose…

Inspired by biological communication systems, molecular communication has been proposed as a viable scheme to communicate between nano-sized devices separated by a very short distance. Here, molecules are released by the transmitter into…

Biological Physics · Physics 2016-11-15 Sachin Kadloor , Raviraj S. Adve , Andrew W. Eckford

Molecular Communication (MC) is a bio-inspired communication method based on the exchange of molecules for information transfer among nanoscale devices. MC has been extensively studied from various aspects in the literature; however, the…

Emerging Technologies · Computer Science 2016-07-26 M. Kuscu , O. B. Akan

Bacterial quorum sensing can be engineered with a view to the design of biotechnological applications based on their intrinsic role as a means of communication. We propose the creation of a positive feedback loop that will promote the…

Cell Behavior · Quantitative Biology 2021-04-15 Daniel P. Martins , Huong Q. -O'Reilly , Lee Coffey , Paul D. Cotter , Sasitharan Balasubramaniam

The biotransport of the intravascular nanoparticle (NP) is influenced by both the complex cellular flow environment and the NP characteristics. Being able to computationally simulate such intricate transport phenomenon with high efficiency…

Fluid Dynamics · Physics 2018-04-24 Zixiang Liu , Yuanzheng Zhu , Rekha R. Rao , Jonathan R. Clausen , Cyrus K. Aidun

A lattice gas model is proposed for investigating the release of drug molecules on devices with semi-permeable, porous membranes in two and three dimensions. The kinetic of this model was obtained through the analytical solution of the…

With the goal of determining strategies to maximise drug delivery to a specific site in the body, we developed a mathematical model for the transport of drug nanocarriers (nanoparticles) in the bloodstream under the influence of an external…

Fluid Dynamics · Physics 2022-08-30 C. Fanelli , K. Kaouri , T. N. Phillips , T. G. Myers , F. Font

Molecular communication is an expanding body of research. Recent advances in biology have encouraged using genetically engineered bacteria as the main component in the molecular communication. This has stimulated a new line of research that…

Information Theory · Computer Science 2012-09-13 Arash Einolghozati , Mohsen Sardari , Faramarz Fekr

Living cells display a remarkable capacity to compartmentalize their functional biochemistry. A particularly fascinating example is the cell nucleus. Exchange of macromolecules between the nucleus and the surrounding cytoplasm does not…

Subcellular Processes · Quantitative Biology 2017-04-19 Ching-Hao Wang , Pankaj Mehta , Michael Elbaum

A closer look at nature has recently brought more interest in exploring and utilizing intra-body communication networks composed of cells as intrinsic, perfectly biocompatible infrastructures to deliver therapeutics. Naturally occurring…

Signal Processing · Electrical Eng. & Systems 2022-07-06 Hamid Khoshfekr Rudsari , Mohammad Zoofaghari , Mladen Veletic , Jacob Bergsland , Ilangko Balasingham

Efficient and non-invasive techniques of cargo delivery to biological cells are the focus of biomedical research because of their great potential importance for targeted drug therapy. Therefore, much effort is being made to study the…

The use of nanoparticles for targeted drug delivery, especially in diseased arteries, is a novel procedure. We are incorporating nanoparticles into blood vessels using a catheter, which could potentially deliver drugs precisely to affected…

Fluid Dynamics · Physics 2023-08-31 Surabhi Rathore , Dasari Srikanth

As one of the most prevalent diseases worldwide, plaque formation in human arteries, known as atherosclerosis, is the focus of many research efforts. Previously, molecular communication (MC) models have been proposed to capture and analyze…

The recently emerged molecular communication (MC) paradigm intends to leverage communication engineering tools for the design of synthetic chemical communication systems. These systems are envisioned to operate at nanoscale and in…

Information Theory · Computer Science 2024-04-05 Lukas Brand , Yan Wang , Maurizio Magarini , Robert Schober , Sebastian Lotter

Cellulose nanocrystals (CNC) are naturally-derived nanostructures of growing importance for the production of composites having attractive mechanical properties, and offer improved sustainability over purely petroleum-based alternatives.…

Soft Condensed Matter · Physics 2019-01-15 Abhinav Rao , Thibaut Divoux , Gareth H. McKinley , A. John Hart

Motivated by the numerous healthcare applications of molecular communication (MC) inside blood vessels, this work considers relay/cooperative nanomachine (CN)-assisted mobile MC between a source nanomachine (SN) and a destination…

Information Theory · Computer Science 2018-05-28 Neeraj Varshney , Adarsh Patel , Werner Haselmayr , Aditya K. Jagannatham , Pramod K. Varshney , Weisi Guo

Drug-loaded hydrogels provide a means to deliver pharmaceutical agents to specific sites within the body at a controlled rate. The aim of this paper is to understand how controlled drug release can be achieved by tuning the initial…

Optimization and Control · Mathematics 2022-02-07 Matthew J. Penn , Matthew G. Hennessy