English
Related papers

Related papers: Evaluating Retrieval-Augmented Generation vs. Long…

200 papers

Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

Processing long contexts presents a significant challenge for large language models (LLMs). While recent advancements allow LLMs to handle much longer contexts than before (e.g., 32K or 128K tokens), it is computationally expensive and can…

Computation and Language · Computer Science 2025-04-10 Hongjin Qian , Zheng Liu , Peitian Zhang , Kelong Mao , Defu Lian , Zhicheng Dou , Tiejun Huang

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with…

Artificial Intelligence · Computer Science 2025-11-21 Deepthi Potluri , Aby Mammen Mathew , Jeffrey B DeWitt , Alexander L. Rasgon , Yide Hao , Junyuan Hong , Ying Ding

Although Large Language Models (LLMs) demonstrate significant capabilities, their reliance on parametric knowledge often leads to inaccuracies. Retrieval Augmented Generation (RAG) mitigates this by incorporating external knowledge, but…

Artificial Intelligence · Computer Science 2025-11-04 Hailong Yin , Bin Zhu , Jingjing Chen , Chong-Wah Ngo

Retrieval-augmented generation (RAG) empowers large language models (LLMs) to utilize external knowledge sources. The increasing capacity of LLMs to process longer input sequences opens up avenues for providing more retrieved information,…

Computation and Language · Computer Science 2024-10-10 Bowen Jin , Jinsung Yoon , Jiawei Han , Sercan O. Arik

In high-stakes information domains such as healthcare, where large language models (LLMs) can produce hallucinations or misinformation, retrieval-augmented generation (RAG) has been proposed as a mitigation strategy, grounding model outputs…

Information Retrieval · Computer Science 2026-04-07 Saeedeh Javadi , Sara Mirabi , Manan Gangar , Bahadorreza Ofoghi

Large Language Models (LLMs) excel in data synthesis but can be inaccurate in domain-specific tasks, which retrieval-augmented generation (RAG) systems address by leveraging user-provided data. However, RAGs require optimization in both…

Computation and Language · Computer Science 2024-11-05 Kazi Ahmed Asif Fuad , Lizhong Chen

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Large language models (LLMs) inevitably exhibit hallucinations since the accuracy of generated texts cannot be secured solely by the parametric knowledge they encapsulate. Although retrieval-augmented generation (RAG) is a practicable…

Computation and Language · Computer Science 2024-10-08 Shi-Qi Yan , Jia-Chen Gu , Yun Zhu , Zhen-Hua Ling

Retrieval-augmented generation (RAG) systems rely on retrieval models for identifying relevant contexts and answer generation models for utilizing those contexts. However, retrievers exhibit imperfect recall and precision, limiting…

Computation and Language · Computer Science 2026-04-29 Jerry Huang , Siddarth Madala , Risham Sidhu , Cheng Niu , Hao Peng , Julia Hockenmaier , Tong Zhang

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

The efficient processing of long context poses a serious challenge for large language models (LLMs). Recently, retrieval-augmented generation (RAG) has emerged as a promising strategy for this problem, as it enables LLMs to make selective…

Computation and Language · Computer Science 2025-02-18 Kun Luo , Zheng Liu , Peitian Zhang , Hongjin Qian , Jun Zhao , Kang Liu

Retrieval-Augmented Generation (RAG) enhances Large Language Model (LLM) output by providing prior knowledge as context to input. This is beneficial for knowledge-intensive and expert reliant tasks, including legal question-answering, which…

Retrieval-Augmented Generation (RAG) is a framework for grounding Large Language Models (LLMs) in external, up-to-date information. However, recent advancements in context window size allow LLMs to process inputs of up to 128K tokens or…

Machine Learning · Computer Science 2026-02-26 Seongwoong Shim , Myunsoo Kim , Jae Hyeon Cho , Byung-Jun Lee