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Recent advances in clinical AI have enabled remarkable progress across many clinical domains. However, existing benchmarks and models are primarily limited to a small set of modalities and tasks, which hinders the development of large-scale…

Machine Learning · Computer Science 2025-03-21 Wei Dai , Peilin Chen , Malinda Lu , Daniel Li , Haowen Wei , Hejie Cui , Paul Pu Liang

To address challenges in the digital economy's landscape of digital intelligence, large language models (LLMs) have been developed. Improvements in computational power and available resources have significantly advanced LLMs, allowing their…

Computation and Language · Computer Science 2024-05-24 Yanxin Zheng , Wensheng Gan , Zefeng Chen , Zhenlian Qi , Qian Liang , Philip S. Yu

Generative artificial intelligence (AI) has brought revolutionary innovations in various fields, including medicine. However, it also exhibits limitations. In response, retrieval-augmented generation (RAG) provides a potential solution,…

Artificial Intelligence · Computer Science 2024-06-19 Rui Yang , Yilin Ning , Emilia Keppo , Mingxuan Liu , Chuan Hong , Danielle S Bitterman , Jasmine Chiat Ling Ong , Daniel Shu Wei Ting , Nan Liu

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Large Language Models (LLMs) have shown impressive potential in clinical question answering (QA), with Retrieval Augmented Generation (RAG) emerging as a leading approach for ensuring the factual accuracy of model responses. However,…

Computation and Language · Computer Science 2025-07-21 Mohita Chowdhury , Yajie Vera He , Jared Joselowitz , Aisling Higham , Ernest Lim

The integration of artificial intelligence (AI) into medical diagnostic workflows requires robust and consistent evaluation methods to ensure reliability, clinical relevance, and the inherent variability in expert judgments. Traditional…

We present an advanced approach to medical question-answering (QA) services, using fine-tuned Large Language Models (LLMs) to improve the accuracy and reliability of healthcare information. Our study focuses on optimizing models like…

Computation and Language · Computer Science 2024-10-22 Ali Anaissi , Ali Braytee , Junaid Akram

Reasoning-based large language models have excelled in mathematics and programming, yet their potential in knowledge-intensive medical question answering remains underexplored and insufficiently validated in clinical contexts. To bridge…

Computation and Language · Computer Science 2025-10-10 Yu Sun , Xingyu Qian , Weiwen Xu , Hao Zhang , Chenghao Xiao , Long Li , Deli Zhao , Wenbing Huang , Tingyang Xu , Qifeng Bai , Yu Rong

We present MedConceptsQA, a dedicated open source benchmark for medical concepts question answering. The benchmark comprises of questions of various medical concepts across different vocabularies: diagnoses, procedures, and drugs. The…

Computation and Language · Computer Science 2024-05-15 Ofir Ben Shoham , Nadav Rappoport

Question answering (QA) has achieved promising progress recently. However, answering a question in real-world scenarios like the medical domain is still challenging, due to the requirement of external knowledge and the insufficient quantity…

Artificial Intelligence · Computer Science 2019-12-10 Sheng Shen , Yaliang Li , Nan Du , Xian Wu , Yusheng Xie , Shen Ge , Tao Yang , Kai Wang , Xingzheng Liang , Wei Fan

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Recent advances in machine learning have made revolutionary breakthroughs in computer games, image and natural language understanding, and scientific discovery. Foundation models and large-scale language models (LLMs) have recently achieved…

Neurons and Cognition · Quantitative Biology 2023-10-31 Ran Wang , Zhe Sage Chen

Large-language models have recently demonstrated impressive zero-shot capabilities in a variety of natural language tasks such as summarization, dialogue generation, and question-answering. Despite many promising applications in clinical…

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Advances in computing power, deep learning architectures, and expert labelled datasets have spurred the development of medical imaging artificial intelligence systems that rival clinical experts in a variety of scenarios. The National…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Rohan Shad , John P. Cunningham , Euan A. Ashley , Curtis P. Langlotz , William Hiesinger

Developing AI models that are useful in clinical practice, requires efficient collaboration between clinicians and AI developers. This poses a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Zihao Zhao , Frederik Hauke , Juliana De Castilhos , Mathis Bode , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

We evaluate the impact of large language model-based clinical decision support in live care. In partnership with Penda Health, a network of primary care clinics in Nairobi, Kenya, we studied AI Consult, a tool that serves as a safety net…