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With the advent of generative modeling techniques, synthetic data and its use has penetrated across various domains from unstructured data such as image, text to structured dataset modeling healthcare outcome, risk decisioning in financial…

Machine Learning · Computer Science 2021-05-11 Aman Gupta , Deepak Bhatt , Anubha Pandey

The ''Propose-Test-Release'' (PTR) framework is a classic recipe for designing differentially private (DP) algorithms that are data-adaptive, i.e. those that add less noise when the input dataset is nice. We extend PTR to a more general…

Machine Learning · Computer Science 2023-01-03 Rachel Redberg , Yuqing Zhu , Yu-Xiang Wang

Clinical trials are typically run in order to understand the effects of a new treatment on a given population of patients. However, patients in large populations rarely respond the same way to the same treatment. This heterogeneity in…

Machine Learning · Statistics 2024-02-12 Alihan Hüyük , Zhaozhi Qian , Mihaela van der Schaar

Dynamic treatment regimes (DTRs) consist of a sequence of decision rules, one per stage of intervention, that finds effective treatments for individual patients according to patient information history. DTRs can be estimated from models…

Methodology · Statistics 2021-12-07 Zeyu Bian , Erica EM Moodie , Susan M Shortreed , Sahir Bhatnagar

Clinical trials are essential for drug development but often suffer from expensive, inaccurate and insufficient patient recruitment. The core problem of patient-trial matching is to find qualified patients for a trial, where patient…

Artificial Intelligence · Computer Science 2021-04-13 Xingyao Zhang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Process mining offers techniques to exploit event data by providing insights and recommendations to improve business processes. The growing amount of algorithms for process discovery has raised the question of which algorithms perform best…

Software Engineering · Computer Science 2018-06-20 Toon Jouck , Alfredo Bolt , Benoît Depaire , Massimiliano de Leoni , Wil M. P. van der Aalst

Multiple hypothesis testing with false discovery rate (FDR) control is a fundamental problem in statistical inference, with broad applications in genomics, drug screening, and outlier detection. In many such settings, researchers may have…

Methodology · Statistics 2026-02-19 Yonghoon Lee , Meshi Bashari , Edgar Dobriban , Yaniv Romano

Synthetic data can improve generalization when real data is scarce, but excessive reliance may introduce distributional mismatches that degrade performance. In this paper, we present a learning-theoretic framework to quantify the trade-off…

Machine Learning · Statistics 2026-04-02 Amitis Shidani , Tyler Farghly , Yang Sun , Habib Ganjgahi , George Deligiannidis

A platform trial is an innovative clinical trial design that uses a master protocol to evaluate multiple treatments, where patients are often assigned to different subsets of treatment arms based on individual characteristics, enrollment…

Differential privacy (DP) data synthesizers support public release of sensitive information, offering theoretical guarantees for privacy but limited evidence of utility in practical settings. Utility is typically measured as the error on…

The distributed recursion (DR) algorithm is an effective method for solving the pooling problem that arises in many applications. It is based on the well-known P-formulation of the pooling problem, which involves the flow and quality…

Optimization and Control · Mathematics 2024-11-15 Wei-Yang Zhang , Feng-Lian Dong , Zhi-Wei Wei , Yan-Ru Wang , Ze-Jin Xu , Wei-Kun Chen , Yu-Hong Dai

Experimentation is widely utilized for causal inference and data-driven decision-making across disciplines. In an A/B experiment, for example, an online business randomizes two different treatments (e.g., website designs) to their customers…

Methodology · Statistics 2025-01-15 Wenxuan Guo , JungHo Lee , Panos Toulis

Data-driven methods have become paramount in modern systems and control problems characterized by growing levels of complexity. In safety-critical environments, deploying these methods requires rigorous guarantees, a need that has motivated…

Systems and Control · Electrical Eng. & Systems 2025-12-05 Dario Paccagnan , Daniel Marks , Marco C. Campi , Simone Garatti

Recently, deep learning technology has been successfully introduced into Automatic Modulation Recognition (AMR) tasks. However, the success of deep learning is all attributed to the training on large-scale datasets. Such a large amount of…

Machine Learning · Computer Science 2024-08-07 Dongwei Xu , Jiajun Chen , Yao Lu , Tianhao Xia , Qi Xuan , Wei Wang , Yun Lin , Xiaoniu Yang

Randomized experiments are widely used to estimate causal effects across a variety of domains. However, classical causal inference approaches rely on critical independence assumptions that are violated by network interference, when the…

Methodology · Statistics 2022-10-18 Mayleen Cortez , Matthew Eichhorn , Christina Lee Yu

Estimating individualized treatment rules (ITRs) is fundamental to precision medicine, where the goal is to tailor treatment decisions to individual patient characteristics. While numerous methods have been developed for ITR estimation,…

Methodology · Statistics 2026-05-15 Eun Jeong Oh , Min Qian

Next-generation sequencing technologies now constitute a method of choice to measure gene expression. Data to analyze are read counts, commonly modeled using Negative Binomial distributions. A relevant issue associated with this…

Methodology · Statistics 2014-11-10 Elisabetta Bonafede , Franck Picard , Stéphane Robin , Cinzia Viroli

It is essential but challenging to share medical image datasets due to privacy issues, which prohibit building foundation models and knowledge transfer. In this paper, we propose a novel dataset distillation method to condense the original…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Zhen Yu , Yang Liu , Qingchao Chen

Parallel dataflow systems are a central part of most analytic pipelines for big data. The iterative nature of many analysis and machine learning algorithms, however, is still a challenge for current systems. While certain types of bulk…

Databases · Computer Science 2012-08-02 Stephan Ewen , Kostas Tzoumas , Moritz Kaufmann , Volker Markl

Large language models often struggle with complex long-horizon analytical tasks over unstructured tables, which typically feature hierarchical and bidirectional headers and non-canonical layouts. We formalize this challenge as Deep Tabular…

Artificial Intelligence · Computer Science 2026-03-13 Junnan Dong , Chuang Zhou , Zheng Yuan , Yifei Yu , Qiufeng Wang , Yinghui Li , Siyu An , Di Yin , Xing Sun , Feiyue Huang
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