English
Related papers

Related papers: In Silico Evaluation of Cardiac Tissue-Engineered …

200 papers

For plane-wave and many-spiral states of the experimentally based Luo-Rudy 1 model of heart tissue in large (8 cm square) domains, we show that an explicit space-time-adaptive time-integration algorithm can achieve an order of magnitude…

Computational Physics · Physics 2009-10-31 Elizabeth M. Cherry , Henry S. Greenside , Craig S. Henriquez

Automatic segmentation of myocardial contours and relevant areas like infraction and no-reflow is an important step for the quantitative evaluation of myocardial infarction. In this work, we propose a cascaded convolutional neural network…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Yichi Zhang

The Electrocardiograph signal represents the heart's electrical activity while blood pressure results from the heart's mechanical activity. Previous studies have investigated how the heart's electrical and mechanical activities are related…

Signal Processing · Electrical Eng. & Systems 2020-08-25 Seyedeh Somayyeh Mousavi , Mostafa Charmi , Mohammad Firouzmand , Mohammad Hemmati , Maryam Moghadam , Yadollah Ghorbani

Traditionally, cardiac surgery has been performed through a median sternotomy, which allows the surgeon generous access to the heart and surrounding great vessels. As a paradigm shift in the size and location of incisions occurs in cardiac…

Robotics · Computer Science 2007-05-23 Alan P. Kypson , W. Randolph Chitwood

Atrial fibrillation is a clinical arrhythmia with multifactorial mechanisms still unresolved. Time-frequency analysis of epicardial electrograms has been investigated to study atrial fibrillation. However, deeper understanding of atrial…

Signal Processing · Electrical Eng. & Systems 2019-10-15 Miao Sun , Elvin Isufi , Natasja M. S. de Groot , Richard C. Hendriks

Accurate segmentation and motion estimation of myocardium have always been important in clinic field, which essentially contribute to the downstream diagnosis. However, existing methods cannot always guarantee the shape integrity for…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Xiaoling Hu , Xiao Chen , Yikang Liu , Eric Z. Chen , Terrence Chen , Shanhui Sun

Spiral waves of excitation in cardiac tissue are associated with life-threatening cardiac arrhythmias. It is, therefore, important to study the electrophysiological factors that affect the dynamics of these spiral waves. By using an…

Biological Physics · Physics 2021-08-17 Mahesh Kumar Mulimani , Soling Zimik , Rahul Pandit

3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and the diagnosis of cardiovascular diseases. Current state-of-the art methods focus on estimating dense…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Qingjie Meng , Wenjia Bai , Declan P O'Regan , and Daniel Rueckert

Accurate segmentation of aortic vascular structures is critical for diagnosing and treating cardiovascular diseases.Traditional Transformer-based models have shown promise in this domain by capturing long-range dependencies between vascular…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenxi Zhang , Fuchen Zheng , Adnan Iltaf , Yifei Han , Zhenyu Cheng , Yue Du , Bin Li , Tianyong Liu , Shoujun Zhou

Cerebral vasospasm, a prolonged constriction of cerebral arteries, is the first cause of morbidity and mortality for patients who survive hospitalisation after aneurysmal subarachnoid haemorrhage. The recent finding that stent-retrievers…

Computational Engineering, Finance, and Science · Computer Science 2024-09-02 Giulia Pederzani , Andrii Grytsan , Alfons G. Hoekstra , Anne M. Robertson , Paul N. Watton

Electrocardiographic imaging non-invasively reconstructs activation maps of the heart from temporal body surface potential maps by post-processing solutions of an inverse problem. Typically, activation times are detected through the maximal…

Analysis of PDEs · Mathematics 2024-12-02 Emma Lagracie , Lisl Weynans , Yves Coudière

Human organs are composed of interconnected substructures whose geometry and spatial relationships constrain one another. Yet, most deep-learning approaches treat these parts independently, producing anatomically implausible…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Deniz Sayin Mercadier , Hieu Le , Yihong Chen , Jiancheng Yang , Udaranga Wickramasinghe , Pascal Fua

A significant hallmark of hypertrophic cardiomyopathy (HCM) is fiber disarray, which is associated with various cardiac events such as heart failure. Quantifying fiber disarray remains critical for understanding the disease s complex…

Tissues and Organs · Quantitative Biology 2025-07-04 Mohammad Mehri , Kenneth S. Campbell , Lik Chuan Lee , Jonathan F. Wenk

The mechanisms underlying cardiac fibrillation have been investigated for over a century, but we are still finding surprising results that change our view of this phenomenon. The present study focuses on the transition from normal rhythm to…

Tissues and Organs · Quantitative Biology 2024-11-15 Alejandro Garzón , Roman O. Grigoriev

As part of applications dealing with cardiovascular tissue engineering, drop-cast polyvinylidene fluoride (PVDF) scaffolds have been treated by cold plasma to enhance their adherence to cardiac cells. The scaffolds were treated in a…

Heart transplant patients are followed with periodic right heart catheterizations (RHCs) to identify post-transplant complications and guide treatment. Post-transplant positive outcomes are associated with a steady reduction of right…

Tissues and Organs · Quantitative Biology 2019-12-11 Amanda L. Colunga , Karam G. Kim , N. Payton Woodall , Todd F. Dardas , John H. Gennari , Mette S. Olufsen , Brian E. Carlson

Elucidating the biomechanical behavior of the myocardium is crucial for understanding cardiac physiology, but cannot be directly inferred from clinical imaging and typically requires finite element (FE) simulations. However, conventional FE…

Medical Physics · Physics 2025-06-27 Siyu Mu , Wei Xuan Chan , Choon Hwai Yap

This study presents a novel methodology for stratifying post-myocardial infarction patients at risk of ventricular arrhythmias using patient-specific 3D cardiac models derived from late gadolinium enhancement cardiovascular magnetic…

Computational Engineering, Finance, and Science · Computer Science 2024-09-11 Dolors Serra , Pau Romero , Paula Franco , Ignacio Bernat , Miguel Lozano , Ignacio Garcia-Fernandez , David Soto , Antonio Berruezo , Oscar Camara , Rafael Sebastian

Soft composite solids, comprising discrete inclusions embedded within a compliant matrix, are emerging candidates for engineering synthetic tissues and soft robotic materials. Current strategies for controlling their nonlinear mechanics,…

Soft Condensed Matter · Physics 2026-04-23 Yiqiu Zhao , Deng Pan , Yiming Pang , Jonathan Barés , Chang Xu , Che Liu , Haitao Hu , Yuliang Jin , Qin Xu