Related papers: In Silico Evaluation of Cardiac Tissue-Engineered …
Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to regenerative tissue engineering. Yet, alongside these potential…
The introduction of computational models in cardiovascular sciences has been progressively bringing new and unique tools for the investigation of the physiopathology. Together with the dramatic improvement of imaging and measuring devices…
Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…
The assessment of myocardial fiber disarray is of major interest for the study of the progression of myocardial disease. However, time-resolved imaging of the myocardial structure remains unavailable in clinical practice. In this study, we…
One of the challenges in the development of patient-specific models of cardiac arrhythmias for clinical applications has been accounting for myocardial fiber organization. The fiber varies significantly from heart to heart, but cannot be…
Purpose: Advancements in MRI Tissue Phase Velocity Mapping (TPM) allow for the acquisition of higher quality velocity cardiac images providing better assessment of regional myocardial deformation for accurate disease diagnosis,…
Background. Most surgical procedures involve structures deeper than the skin. However, the difference in surgical noxious stimulation between skin incision and laparoscopic trocar insertion is unknown. By analyzing instantaneous heart rate…
Excitable membranes are an important type of nonlinear dynamical system and their study can be used to provide a connection between physical and biological circuits. We discuss two models of excitable membranes important in cardiac and…
Cardiac re-entry regime of self-organised abnormal synchronisation underlie dangerous arrhythmias and fatal fibrillation. Recent advances in the theory of dissipative vortices, experimental studies, and anatomically realistic computer…
Carotid artery plaques can cause arterial vascular diseases such as stroke and myocardial infarction, posing a severe threat to human life. However, the current clinical examination mainly relies on a direct assessment by physicians of…
Interest in the application of engineering methods to problems in congenital heart disease has gained increased popularity over the past decade. The use of computational simulation to examine common clinical problems including single…
The motion of and interaction between phase singularities that anchor spiral waves captures many qualitative and, in some cases, quantitative features of complex dynamics in excitable systems. Being able to accurately reconstruct their…
The aim of this study is to use image-processing techniques developed in the field of astrophysics as inspiration for a novel approach to the three-dimensional (3D) imaging of periprocedural medical data, with the intention of providing…
Prismatic sandwich panels fabricated from metals offer a compelling alternative to more traditional panels across diverse industries, primarily due to their superior strength-to-weight ratio. Although several core types were proposed in the…
The 3D volumetric shape of the heart's left ventricle (LV) myocardium (MYO) wall provides important information for diagnosis of cardiac disease and invasive procedure navigation. Many cardiac image segmentation methods have relied on…
In this study, palpating and rolling arteries with different physical properties and tactile distinction of them from each other, using finite element method, are presented. Five models have been created: healthy artery containing blood,…
Background-The electric field applied to the heart during defibrillation causes mechanical forces (electrostriction), and as a result the heart deforms. This paper analyses the physical origin of the deformation, and how significant it is.…
Extracellular matrix (ECM) remodeling is central to a wide variety of healthy and diseased tissue processes. Unfortunately, predicting ECM remodeling under various chemical and mechanical conditions has proven to be excessively challenging,…
Understanding the viability of the ischemic myocardial tissue is a critical issue in determining the appropriate surgical procedure for patients with chronic heart failure after myocardial infarction (MI). Conventional MI evaluation methods…
Precisely controlling the shape of the printed-layers, eliminating the curved sides and internal stress concentration, and increasing the mechanical properties are essential to guarantee the quality of 3D printed cement-based structures.…