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In longitudinal studies, we observe measurements of the same variables at different time points to track the changes in their pattern over time. In such studies, scheduling of the data collection waves (i.e. time of participants' visits) is…

Methodology · Statistics 2020-04-30 Li Xing , Xuekui Zhang , Ardo van den Hout , Scott Hofer , Graciela Muniz Terrera

We construct optimal designs for group testing experiments where the goal is to estimate the prevalence of a trait by using a test with uncertain sensitivity and specificity. Using optimal design theory for approximate designs, we show that…

Statistics Theory · Mathematics 2017-01-05 Shih-Hao Huang , Mong-Na Lo Huang , Kerby Shedden , Weng Kee Wong

In an order-of-addition experiment, each treatment is a permutation of m components. It is often unaffordable to test all the m! treatments, and the design problem arises. We consider a model that incorporates the order of each pair of…

Statistics Theory · Mathematics 2018-05-15 Jiayu Peng , Rahul Mukerjee , Dennis K. J. Lin

In the group-testing literature, efficient algorithms have been developed to minimize the number of tests required to identify all minimal "defective" sub-groups embedded within a larger group, using deterministic group splitting with a…

Discrete Mathematics · Computer Science 2020-10-20 Laurence A. Clarfeld , Margaret J. Eppstein

Test bots are automated testing tools that autonomously and periodically run a set of test cases that check whether the system under test meets the requirements set forth by the customer. The automation decreases the amount of time a…

Software Engineering · Computer Science 2020-04-22 Linda Erlenhov , Francisco Gomes de Oliveira Neto , Martin Chukaleski , Samer Daknache

This paper deals exclusively with crossover designs for the purpose of comparing t test treatments with a control treatment when the number of periods is no larger than t+1. Among other results it specifies sufficient conditions for a…

Statistics Theory · Mathematics 2007-06-13 A. S. Hedayat , Min Yang

For large classes of group testing problems, we derive lower bounds for the probability that all significant items are uniquely identified using specially constructed random designs. These bounds allow us to optimize parameters of the…

Statistics Theory · Mathematics 2022-02-17 Jack Noonan , Anatoly Zhigljavsky

The structural design process for buildings is time-consuming and laborious. To automate this process, structural engineers combine optimization methods with simulation tools to find an optimal design with minimal building mass subject to…

Machine Learning · Computer Science 2020-08-14 Kai-Hung Chang , Chin-Yi Cheng

Statistical design of experiments is widely used in scientific and industrial investigations. A generalized minimum aberration (GMA) orthogonal array is optimum under the well-established, so-called GMA criterion, and such an array can…

Computation · Statistics 2021-04-27 Dursun A. Bulutoglu , Kenneth J. Ryan

In many real-life scenarios, system failure depends on dynamic stress-strength interference, where strength degrades and stress accumulates concurrently over time. In this paper, we consider the problem of finding an optimal replacement…

Applications · Statistics 2022-01-04 Phalguni Nanda , Prajamitra Bhuyan , Anup Dewanji

Many chemical and biological experiments involve multiple treatment factors and often it is convenient to fit a nonlinear model in these factors. This nonlinear model can be mechanistic, empirical or a hybrid of the two. Motivated by…

Computation · Statistics 2018-10-09 Yuanzhi Huang , Steven Gilmour , Kalliopi Mylona , Peter Goos

Experimental design is a classical statistics problem and its aim is to estimate an unknown $m$-dimensional vector $\beta$ from linear measurements where a Gaussian noise is introduced in each measurement. For the combinatorial experimental…

Machine Learning · Statistics 2024-12-06 Mohit Singh , Weijun Xie

In industrial engineering and manufacturing, quality control is an essential part of the production process of a product. To ensure proper functionality of a manufactured good, rigorous testing has to be performed to identify defective…

Methodology · Statistics 2025-04-02 Michael Balzer

This paper presents a quasi-sequential optimal design framework for toxicology experiments, specifically applied to sea urchin embryos. The authors propose a novel approach combining robust optimal design with adaptive, stage-based testing…

Methodology · Statistics 2025-03-04 Elvis Han Cui , Michael Collins , Jessica Munson , Weng Kee Wong

Electric machine design optimization is a computationally expensive multi-objective optimization problem. While the objectives require time-consuming finite element analysis, optimization constraints can often be based on mathematical…

Neural and Evolutionary Computing · Computer Science 2022-06-06 Bhuvan Khoshoo , Julian Blank , Thang Q. Pham , Kalyanmoy Deb , Shanelle N. Foster

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

Applications · Statistics 2014-07-22 Xiao Lin , Gabriel Terejanu

We consider the problem of designing experiments for the comparison of two regression curves describing the relation between a predictor and a response in two groups, where the data between and within the group may be dependent. In order to…

Statistics Theory · Mathematics 2021-01-15 Kirsten Schorning , Holger Dette

In this paper, gradient-based optimization methods are combined with finite-element modeling for improving electric devices. Geometric design parameters are considered by affine decomposition of the geometry or by the design element…

Group testing is concerned with identifying $t$ defective items in a set of $m$ items, where each test reports whether a specific subset of items contains at least one defective. In non-adaptive group testing, the subsets to be tested are…

Computational Geometry · Computer Science 2020-12-03 Benjamin Aram Berendsohn , László Kozma

This research is motivated by the need for effective classification in ice-breaking dynamic simulations, aimed at determining the conditions under which an underwater vehicle will break through the ice. This simulation is extremely…

Methodology · Statistics 2025-06-05 Tian Bai , Dianpeng Wang , Kuangqi Chen , Xu He