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Designing and analysis of test cases is a challenging tasks for tester roles especially those who are related to test the structure of program. Recently, Programmers are showing valuable trend towards the implementation of recursive modules…

Software Engineering · Computer Science 2012-08-28 Muhammad Javed , Bashir Ahmad , Zaffar Abbas , Allah Nawaz , Muhammad Ali Abid , Ihsan Ullah

Degradation models play a critical role in quality engineering by enabling the assessment and prediction of system reliability based on data. The objective of this paper is to provide an accessible introduction to degradation models. We…

We study experiment design for unique identification of the causal graph of a simple SCM, where the graph may contain cycles. The presence of cycles in the structure introduces major challenges for experiment design as, unlike acyclic…

Machine Learning · Computer Science 2023-12-15 Ehsan Mokhtarian , Saber Salehkaleybar , AmirEmad Ghassami , Negar Kiyavash

Model-based experimental design is attracting increasing attention in chemical process engineering. Typically, an iterative procedure is pursued: an approximate model is devised, prescribed experiments are then performed and the resulting…

Optimization and Control · Mathematics 2021-01-25 Charlie Vanaret , Philipp Seufert , Jan Schwientek , Gleb Karpov , Gleb Ryzhakov , Ivan Oseledets , Norbert Asprion , Michael Bortz

Optimization problems are crucial in artificial intelligence. Optimization algorithms are generally used to adjust the performance of artificial intelligence models to minimize the error of mapping inputs to outputs. Current evaluation…

Artificial Intelligence · Computer Science 2021-11-23 Zhicheng He

We review typical design problems encountered in the planning of observational studies and propose a unifying framework that allows us to use the same concepts and notation for different problems. In the framework, the design is defined as…

Statistics Theory · Mathematics 2017-11-02 Juha Karvanen , Jarno Vanhatalo , Kari Auranen , Sangita Kulathinal , Samu Mäntyniemi

Optimal experimental designs are probability measures with finite support enjoying an optimality property for the computation of least squares estimators. We present an algorithm for computing optimal designs on finite sets based on the…

Numerical Analysis · Mathematics 2022-01-11 Federico Piazzon

In this paper, we consider the problem of designing optimal pooling matrix for group testing (for example, for COVID-19 virus testing) with the constraint that no more than $r>0$ samples can be pooled together, which we call "dilution…

Quantitative Methods · Quantitative Biology 2020-08-06 Jirong Yi , Myung Cho , Xiaodong Wu , Raghu Mudumbai , Weiyu Xu

We develop adaptive discretization algorithms for locally optimal experimental design of nonlinear prediction models. With these algorithms, we refine and improve a pertinent state-of-the-art algorithm in various respects. We establish…

Optimization and Control · Mathematics 2024-06-04 Jochen Schmid , Philipp Seufert , Michael Bortz

We consider design issues for toxicology studies when we have a continuous response and the true mean response is only known to be a member of a class of nested models. This class of non-linear models was proposed by toxicologists who were…

Statistics Theory · Mathematics 2010-11-29 Holger Dette , Andrey Pepelyshev , Piter Shpilev , Weng Kee Wong

We design optimal $2 \times N$ ($2 <N$) matrices, with unit columns, so that the maximum condition number of all the submatrices comprising 3 columns is minimized. The problem has two applications. When estimating a 2-dimensional signal by…

Information Theory · Computer Science 2012-12-17 Hema Kumari Achanta , Weiyu Xu , Soura Dasgupta

In this article the most fundamental decomposition-based optimization method - block coordinate search, based on the sequential decomposition of problems in subproblems - and building performance simulation programs are used to reason about…

Optimization and Control · Mathematics 2016-09-12 Gian Luca Brunetti

Efficient algorithms for searching for optimal saturated designs are widely available. They maximize a given efficiency measure (such as D-optimality) and provide an optimum design. Nevertheless, they do not guarantee a \emph{global}…

Computation · Statistics 2013-03-29 Roberto Fontana

We consider the optimal design problem for a comparison of two regression curves, which is used to establish the similarity between the dose response relationships of two groups. An optimal pair of designs minimizes the width of the…

Methodology · Statistics 2014-11-19 Holger Dette , Kirsten Schorning

We develop a novel iterative algorithm for locally optimal experimental design under constraints, like budget or performance constraints. It is an adaptive discretization algorithm. In every iteration, a discretized version of the…

Optimization and Control · Mathematics 2026-04-21 Jochen Schmid , Philipp Seufert , Jan Schwientek , Tobias Seidel , Karl-Heinz Küfer

We study the problem of group testing with non-identical, independent priors. So far, the pooling strategies that have been proposed in the literature take the following approach: a hand-crafted test design along with a decoding strategy is…

Information Theory · Computer Science 2022-01-31 Sundara Rajan Srinivasavaradhan , Pavlos Nikolopoulos , Christina Fragouli , Suhas Diggavi

Accurate parameter dependent electro-chemical numerical models for lithium-ion batteries are essential in industrial application. The exact parameters of each battery cell are unknown and a process of estimation is necessary to infer them.…

Statistics Theory · Mathematics 2024-04-25 Andrea Petrocchi , Matthias K. Scharrer , Franz Pichler , Stefan Volkwein

The determination of an optimal design for a given regression problem is an intricate optimization problem, especially for models with multivariate predictors. Design admissibility and invariance are main tools to reduce the complexity of…

Statistics Theory · Mathematics 2020-03-24 Holger Dette , Xin Liu , Rong-Xian Yue

Group testing is a well-known search problem that consists in detecting of $s$ defective members of a set of $t$ samples by carrying out tests on properly chosen subsets of samples. In classical group testing the goal is to find all…

Information Theory · Computer Science 2020-05-19 Ilya Vorobyev

We typically construct optimal designs based on a single objective function. To better capture the breadth of an experiment's goals, we could instead construct a multiple objective optimal design based on multiple objective functions. While…

Methodology · Statistics 2023-03-09 Lucy L. Gao , Jane J. Ye , Shangzhi Zeng , Julie Zhou