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Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Domain generalization (DG) aims to learn a robust model from source domains that generalize well on unseen target domains. Recent studies focus on generating novel domain samples or features to diversify distributions complementary to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Chenming Li , Daoan Zhang , Wenjian Huang , Jianguo Zhang

Computer-aided detection systems based on deep learning have shown great potential in breast cancer detection. However, the lack of domain generalization of artificial neural networks is an important obstacle to their deployment in changing…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Lidia Garrucho , Kaisar Kushibar , Socayna Jouide , Oliver Diaz , Laura Igual , Karim Lekadir

Model generalization capacity at domain shift (e.g., various imaging protocols and scanners) is crucial for deep learning methods in real-world clinical deployment. This paper tackles the challenging problem of domain generalization, i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Quande Liu , Qi Dou , Pheng-Ann Heng

Recently, considerable effort has been devoted to deep domain adaptation in computer vision and machine learning communities. However, most of existing work only concentrates on learning shared feature representation by minimizing the…

Machine Learning · Computer Science 2019-04-24 Chao Chen , Zhihong Chen , Boyuan Jiang , Xinyu Jin

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Accurate diagnosis of pediatric brain tumors, starting with histopathology, presents unique challenges for deep learning, including severe data scarcity, class imbalance, and fine-grained morphologic overlap across diagnostically distinct…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Joakim Nguyen , Jian Yu , Jinrui Fang , Nicholas Konz , Tianlong Chen , Sanjay Krishnan , Chandra Krishnan , Ying Ding , Hairong Wang , Ankita Shukla

Deep Neural Networks (DNNs) suffer from domain shift when the test dataset follows a distribution different from the training dataset. Domain generalization aims to tackle this issue by learning a model that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2022-12-15 Yu Ding , Lei Wang , Bin Liang , Shuming Liang , Yang Wang , Fang Chen

Histopathology image embedding is an active research area in computer vision. Most of the embedding models exclusively concentrate on a specific magnification level. However, a useful task in histopathology embedding is to train an…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Milad Sikaroudi , Benyamin Ghojogh , Fakhri Karray , Mark Crowley , H. R. Tizhoosh

We provide in this paper a comprehensive comparison of various transfer learning strategies and deep learning architectures for computer-aided classification of adult-type diffuse gliomas. We evaluate the generalizability of out-of-domain…

Despite the recent success of domain generalization in medical image segmentation, voxel-wise annotation for all source domains remains a huge burden. Semi-supervised domain generalization has been proposed very recently to combat this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Muyang Qiu , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Distributional shift between domains poses great challenges to modern machine learning algorithms. The domain generalization (DG) signifies a popular line targeting this issue, where these methods intend to uncover universal patterns across…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Hao Chen , Qi Zhang , Zenan Huang , Haobo Wang , Junbo Zhao

Domain generalization aims to train models on multiple source domains so that they can generalize well to unseen target domains. Among many domain generalization methods, Fourier-transform-based domain generalization methods have gained…

Image and Video Processing · Electrical Eng. & Systems 2023-12-14 Hongyi Pan , Bin Wang , Zheyuan Zhang , Xin Zhu , Debesh Jha , Ahmet Enis Cetin , Concetto Spampinato , Ulas Bagci

Generalising deep models to new data from new centres (termed here domains) remains a challenge. This is largely attributed to shifts in data statistics (domain shifts) between source and unseen domains. Recently, gradient-based…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Xiao Liu , Spyridon Thermos , Alison O'Neil , Sotirios A. Tsaftaris

Learning the ability to generalize knowledge between similar contexts is particularly important in medical imaging as data distributions can shift substantially from one hospital to another, or even from one machine to another. To…

Computer Vision and Pattern Recognition · Computer Science 2023-11-13 Steven Korevaar , Ruwan Tennakoon , Ricky O'Brien , Dwarikanath Mahapatra , Alireza Bab-Hadiasha

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Deep learning based medical imaging classification models usually suffer from the domain shift problem, where the classification performance drops when training data and real-world data differ in imaging equipment manufacturer, image…

Computer Vision and Pattern Recognition · Computer Science 2022-06-01 Wenshuo Zhou , Dalu Yang , Binghong Wu , Yehui Yang , Junde Wu , Xiaorong Wang , Lei Wang , Haifeng Huang , Yanwu Xu

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…