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Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Hao Guan , Mingxia Liu

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

Generalization capability to unseen domains is crucial for machine learning models when deploying to real-world conditions. We investigate the challenging problem of domain generalization, i.e., training a model on multi-domain source data…

Computer Vision and Pattern Recognition · Computer Science 2019-10-31 Qi Dou , Daniel C. Castro , Konstantinos Kamnitsas , Ben Glocker

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

Domain generalisation aims to promote the learning of domain-invariant features while suppressing domain-specific features, so that a model can generalise better to previously unseen target domains. An approach to domain generalisation for…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Karthik Seemakurthy , Erchan Aptoula , Charles Fox , Petra Bosilj

When domains, which represent underlying data distributions, vary during training and testing processes, deep neural networks suffer a drop in their performance. Domain generalization allows improvements in the generalization performance…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 Toshihiko Matsuura , Tatsuya Harada

Numerous Deep Learning (DL) classification models have been developed for a large spectrum of medical image analysis applications, which promises to reshape various facets of medical practice. Despite early advances in DL model validation…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Sarah Matta , Mathieu Lamard , Philippe Zhang , Alexandre Le Guilcher , Laurent Borderie , Béatrice Cochener , Gwenolé Quellec

Domain Generalization (DG) aims to learn a model that can generalize well to unseen target domains from a set of source domains. With the idea of invariant causal mechanism, a lot of efforts have been put into learning robust causal effects…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 Qiaowei Miao , Junkun Yuan , Kun Kuang

Medical Image Analysis (MedIA) has emerged as a crucial tool in computer-aided diagnosis systems, particularly with the advancement of deep learning (DL) in recent years. However, well-trained deep models often experience significant…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Ziwei Niu , Shuyi Ouyang , Shiao Xie , Yen-wei Chen , Lanfen Lin

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Domain Generalization (DG) is a fundamental challenge for machine learning models, which aims to improve model generalization on various domains. Previous methods focus on generating domain invariant features from various source domains.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Daoan Zhang , Mingkai Chen , Chenming Li , Lingyun Huang , Jianguo Zhang

An organ segmentation method that can generalize to unseen contrasts and scanner settings can significantly reduce the need for retraining of deep learning models. Domain Generalization (DG) aims to achieve this goal. However, most DG…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yanwu Xu , Shaoan Xie , Maxwell Reynolds , Matthew Ragoza , Mingming Gong , Kayhan Batmanghelich

Deep learning models perform best when tested on target (test) data domains whose distribution is similar to the set of source (train) domains. However, model generalization can be hindered when there is significant difference in the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Pulkit Khandelwal , Paul Yushkevich

Domain generalization (DG) has been a hot topic in image recognition, with a goal to train a general model that can perform well on unseen domains. Recently, federated learning (FL), an emerging machine learning paradigm to train a global…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Junming Chen , Meirui Jiang , Qi Dou , Qifeng Chen

Whole slide images~(WSIs) are digitized images of tissues placed in glass slides using advanced scanners. The digital processing of WSIs is challenging as they are gigapixel images and stored in multi-resolution format. A common challenge…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Deep learning models for dermatological image analysis remain sensitive to acquisition variability and domain-specific visual characteristics, leading to performance degradation when deployed in clinical settings. We investigate how visual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Rodrigo Mota , Kelvin Cunha , Emanoel dos Santos , Fábio Papais , Francisco Filho , Thales Bezerra , Erico Medeiros , Paulo Borba , Tsang Ing Ren

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Soham Rohit Chitnis , Sidong Liu , Tirtharaj Dash , Tanmay Tulsidas Verlekar , Antonio Di Ieva , Shlomo Berkovsky , Lovekesh Vig , Ashwin Srinivasan

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 So Won Jeong , Veronika Ročková

Deep learning has become the mainstream methodological choice for analyzing and interpreting whole-slide digital pathology images (WSIs). It is commonly assumed that tumor regions carry most predictive information. In this paper, we…

Quantitative Methods · Quantitative Biology 2022-04-26 Zihan Chen , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

Semantic segmentation models struggle to generalize in the presence of domain shift. In this paper, we introduce contrastive learning for feature alignment in cross-domain adaptation. We assemble both in-domain contrastive pairs and…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Feihu Zhang , Vladlen Koltun , Philip Torr , René Ranftl , Stephan R. Richter