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Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Domain shift in the field of histopathological imaging is a common phenomenon due to the intra- and inter-hospital variability of staining and digitization protocols. The implementation of robust models, capable of creating generalized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Ilán Carretero , Pablo Meseguer , Rocío del Amor , Valery Naranjo

Traditional domain generalization methods often rely on domain alignment to reduce inter-domain distribution differences and learn domain-invariant representations. However, domain shifts are inherently difficult to eliminate, which limits…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuheng Xu , Taiping Zhang

The domain shift in pathological segmentation is an important problem, where a network trained by a source domain (collected at a specific hospital) does not work well in the target domain (from different hospitals) due to the different…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Xiaoqing Liu , Kengo Araki , Shota Harada , Akihiko Yoshizawa , Kazuhiro Terada , Mariyo Kurata , Naoki Nakajima , Hiroyuki Abe , Tetsuo Ushiku , Ryoma Bise

The domain generalization problem has been widely investigated in deep learning for non-contrast imaging over the last years, but it received limited attention for contrast-enhanced imaging. However, there are marked differences in contrast…

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Efficiently utilizing discriminative features is crucial for convolutional neural networks to achieve remarkable performance in medical image segmentation and is also important for model generalization across multiple domains, where letting…

Computer Vision and Pattern Recognition · Computer Science 2022-05-16 Ran Gu , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Xiaofan Zhang , Guotai Wang , Shaoting Zhang

In AI-based histopathology, domain shifts are common and well-studied. However, this research focuses on stain and scanner variations, which do not show the full picture -- shifts may be combinations of other shifts, or "invisible" shifts…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Andrew Walker

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Domain shift is a significant problem in histopathology. There can be large differences in data characteristics of whole-slide images between medical centers and scanners, making generalization of deep learning to unseen data difficult. To…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Karin Stacke , Gabriel Eilertsen , Jonas Unger , Claes Lundström

During the past decade, deep neural networks have led to fast-paced progress and significant achievements in computer vision problems, for both academia and industry. Yet despite their success, state-of-the-art image classification…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Aristotelis Ballas , Christos Diou

Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications. Nevertheless, the presence of out-of-distribution data…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Mostafa Jahanifar , Manahil Raza , Kesi Xu , Trinh Vuong , Rob Jewsbury , Adam Shephard , Neda Zamanitajeddin , Jin Tae Kwak , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Deep learning-based methods deliver state-of-the-art performance for solving inverse problems that arise in computational imaging. These methods can be broadly divided into two groups: (1) learn a network to map measurements to the signal…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Nebiyou Yismaw , Ulugbek S. Kamilov , M. Salman Asif

In real-life applications, machine learning models often face scenarios where there is a change in data distribution between training and test domains. When the aim is to make predictions on distributions different from those seen at…

Machine Learning · Computer Science 2021-11-04 Lucas Mansilla , Rodrigo Echeveste , Diego H. Milone , Enzo Ferrante

Preparing and scanning histopathology slides consists of several steps, each with a multitude of parameters. The parameters can vary between pathology labs and within the same lab over time, resulting in significant variability of the…

Computer Vision and Pattern Recognition · Computer Science 2018-01-11 Maxime W. Lafarge , Josien P. W. Pluim , Koen A. J. Eppenhof , Pim Moeskops , Mitko Veta

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Zheren Li , Zhiming Cui , Lichi Zhang , Sheng Wang , Chenjin Lei , Xi Ouyang , Dongdong Chen , Xiangyu Zhao , Yajia Gu , Zaiyi Liu , Chunling Liu , Dinggang Shen , Jie-Zhi Cheng

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

The limited ability of Convolutional Neural Networks to generalize to images from previously unseen domains is a major limitation, in particular, for safety-critical clinical tasks such as dermoscopic skin cancer classification. In order to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Katharina Fogelberg , Sireesha Chamarthi , Roman C. Maron , Julia Niebling , Titus J. Brinker

We introduce a novel approach to unsupervised and semi-supervised domain adaptation for semantic segmentation. Unlike many earlier methods that rely on adversarial learning for feature alignment, we leverage contrastive learning to bridge…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Weizhe Liu , David Ferstl , Samuel Schulter , Lukas Zebedin , Pascal Fua , Christian Leistner
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