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Predicting individual cognitive decline in Alzheimer's disease (AD) is difficult due to the heterogeneity of disease progression. Reliable clinical tools require not only high accuracy but also fairness across demographics and robustness to…

Artificial Intelligence · Computer Science 2026-04-27 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

The role played by physical activity in slowing down the progression of type-2 diabetes is well recognized. However, except for general clinical guidelines, quantitative real-time estimates of the recommended amount of physical activity,…

Systems and Control · Electrical Eng. & Systems 2025-03-13 Pierluigi Francesco De Paola , Alessandro Borri , Alessia Paglialonga , Pasquale Palumbo , Fabrizio Dabbene

Continuous Blood Glucose (CGM) monitors have revolutionized the ability of diabetics to manage their blood glucose, and paved the way for artificial pancreas systems. In this paper we augment CGM data with sensor input collected by a smart…

Human-Computer Interaction · Computer Science 2023-02-06 Sam Royston

The insulin sensitivity (IS) of the human body changes with a circadian rhythm. This adds to the time-varying feature of the glucose metabolism process and places challenges on the blood glucose (BG) control of patients with Type 1 Diabetes…

Systems and Control · Computer Science 2021-01-29 Lukas Ortmann , Dawei Shi , Eyal Dassau , Francis J. Doyle , Steffen Leonhardt , Berno J. E. Misgeld

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during…

Machine Learning · Computer Science 2024-07-02 Yue Wang , Tianfan Fu , Yinlong Xu , Zihan Ma , Hongxia Xu , Yingzhou Lu , Bang Du , Honghao Gao , Jian Wu

Quantifying the uncertainty in predictive models is critical for establishing trust and enabling risk-informed decision making for personalized medicine. In contrast to one-size-fits-all approaches that seek to mitigate risk at the…

Computational Engineering, Finance, and Science · Computer Science 2025-05-15 Graham Pash , Umberto Villa , David A. Hormuth , Thomas E. Yankeelov , Karen Willcox

Pedestrian dynamics simulates the fine-scaled trajectories of individuals in a crowd. It has been used to suggest public health interventions to reduce infection risk in important components of air travel, such as during boarding and in…

Computers and Society · Computer Science 2024-10-21 Ashok Srinivasan , Satkkeerthi Sriram , Sirish Namilae , Andrew Arash Mahyari

People with diabetes need insulin delivery to effectively manage their blood glucose levels, especially after meals, because their bodies either do not produce enough insulin or cannot fully utilize it. Accurate insulin delivery starts with…

Systems and Control · Electrical Eng. & Systems 2024-11-21 Hanyu Zeng , Hui Ji , Pengfei Zhou

Artificial intelligence (AI) algorithms are a critical part of state-of-the-art digital health technology for diabetes management. Yet, access to large high-quality datasets is creating barriers that impede development of robust AI…

Artificial Intelligence · Computer Science 2025-07-21 Temiloluwa Prioleau , Baiying Lu , Yanjun Cui

Digital twin technology has a huge potential for widespread applications in different industrial sectors such as infrastructure, aerospace, and automotive. However, practical adoptions of this technology have been slower, mainly due to a…

Machine Learning · Statistics 2020-06-16 Souvik Chakraborty , Sondipon Adhikari

People with diabetes must carefully monitor their blood glucose levels, especially after eating. Blood glucose regulation requires a proper combination of food intake and insulin boluses. Glucose prediction is vital to avoid dangerous…

Machine Learning · Computer Science 2023-07-06 Daniel Parra , David Joedicke , J. Manuel Velasco , Gabriel Kronberger , J. Ignacio Hidalgo

Digital twin technology, when combined with physics-informed machine learning with simulation results of Aspen, offers transformative capabilities for industrial process monitoring, control, and optimization. In this work, the proposed…

Machine Learning · Computer Science 2026-03-27 Debadutta Patra , Ayush Bardhan Tripathy , Soumya Ranjan Sahu , Sucheta Panda

Accurate blood glucose prediction can enable novel interventions for type 1 diabetes treatment, including personalized insulin and dietary adjustments. Although recent advances in transformer-based architectures have demonstrated the power…

Quantitative Methods · Quantitative Biology 2025-05-15 Meryem Altin Karagoz , Marc D. Breton , Anas El Fathi

In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 diabetes. We consider three families of sequence models based on LSTM, GRU, and…

Machine Learning · Computer Science 2026-03-31 Hai Siong Tan , Rafe McBeth

Network digital twins (NDTs) facilitate the estimation of key performance indicators (KPIs) before physically implementing a network, thereby enabling efficient optimization of the network configuration. In this paper, we propose a…

Networking and Internet Architecture · Computer Science 2023-06-13 Boning Li , Timofey Efimov , Abhishek Kumar , Jose Cortes , Gunjan Verma , Ananthram Swami , Santiago Segarra

In non-terrestrial networks (NTN), high-speed satellite orbital motion, limited pilot signaling resources, and spatiotemporally heterogeneous traffic make accurate channel and traffic state characterization particularly challenging. In this…

Signal Processing · Electrical Eng. & Systems 2026-05-25 Xinyu Huang , Yixiao Zhang , Xue Qin , Mingcheng He , Junling Li , Weihua Zhuang , Xuemin Shen

Digital twins (DT) have received significant attention due to their numerous benefits, such as real-time data analytics and cost reduction in production. DT serves as a fundamental component of many applications, encompassing smart…

Networking and Internet Architecture · Computer Science 2025-05-08 Chen Chen , Zihan Jia , Ze Wang , Lin Cui , Fung Po Tso

The ability of the Network digital twin (NDT) to remain aware of changes in its physical counterpart, known as the physical twin (PTwin), is a fundamental condition to enable timely synchronization, also referred to as twinning. In this…

Musculoskeletal disorders (MSDs) are a leading cause of disability worldwide, requiring advanced diagnostic and therapeutic tools for personalised assessment and treatment. Effective management of MSDs involves the interaction of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Martina Paccini , Simone Cammarasana , Giuseppe Patanè

Accurate prediction of future blood glucose (BG) levels can effectively improve BG management for people living with diabetes, thereby reducing complications and improving quality of life. The state of the art of BG prediction has been…

Machine Learning · Computer Science 2024-02-27 Chengzhe Piao , Taiyu Zhu , Stephanie E Baldeweg , Paul Taylor , Pantelis Georgiou , Jiahao Sun , Jun Wang , Kezhi Li