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The presence and density of specific types of immune cells are important to understand a patient's immune response to cancer. However, immunofluorescence staining required to identify T cell subtypes is expensive, time-consuming, and rarely…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Georg Wölflein , In Hwa Um , David J Harrison , Ognjen Arandjelović

Obtaining a high-quality frontal face image from a low-resolution (LR) non-frontal face image is primarily important for many facial analysis applications. However, mainstreams either focus on super-resolving near-frontal LR faces or…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Yang Zhang , Ivor W. Tsang , Jun Li , Ping Liu , Xiaobo Lu , Xin Yu

Molecular testing of tumor samples for targetable biomarkers is restricted by a lack of standardization, turnaround-time, cost, and tissue availability across cancer types. Additionally, targetable alterations of low prevalence may not be…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Kshitij Ingale , Sun Hae Hong , Qiyuan Hu , Renyu Zhang , Bo Osinski , Mina Khoshdeli , Josh Och , Kunal Nagpal , Martin C. Stumpe , Rohan P. Joshi

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

Histological examination is crucial for cancer diagnosis, including hematoxylin and eosin (H&E) staining for mapping morphology and immunohistochemistry (IHC) staining for revealing chemical information. Recently developed two-color…

Tissues and Organs · Quantitative Biology 2023-09-22 Hongli Ni , Chinmayee Prabhu Dessai , Haonan Lin , Wei Wang , Shaoxiong Chen , Yuhao Yuan , Xiaowei Ge , Jianpeng Ao , Nolan Vild , Ji-Xin Cheng

This paper presents a novel multi-fake evolutionary generative adversarial network(MFEGAN) for handling imbalance hyperspectral image classification. It is an end-to-end approach in which different generative objective losses are considered…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Tanmoy Dam , Nidhi Swami , Sreenatha G. Anavatti , Hussein A. Abbass

Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Amirata Ghorbani , Vivek Natarajan , David Coz , Yuan Liu

Training robust supervised deep learning models for many geospatial applications of computer vision is difficult due to dearth of class-balanced and diverse training data. Conversely, obtaining enough training data for many applications is…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Xuerong Xiao , Swetava Ganguli , Vipul Pandey

Blood vessels (BVs) play a critical role in the Tumor Micro-Environment (TME), potentially influencing cancer progression and treatment response. However, manually quantifying BVs in Hematoxylin and Eosin (H&E) stained images is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Jiaqi Lv , Stefan S Antonowicz , Shan E Ahmed Raza

Generative adversarial networks (GANs) are a machine learning technique capable of producing high-quality synthetic images. In the field of materials science, when a crystallographic dataset includes inadequate or difficult-to-obtain…

The advent of Generative Adversarial Networks (GANs) has brought about completely novel ways of transforming and manipulating pixels in digital images. GAN based techniques such as Image-to-Image translations, DeepFakes, and other automated…

Computer Vision and Pattern Recognition · Computer Science 2019-10-04 Lakshmanan Nataraj , Tajuddin Manhar Mohammed , Shivkumar Chandrasekaran , Arjuna Flenner , Jawadul H. Bappy , Amit K. Roy-Chowdhury , B. S. Manjunath

The rapid progress in deep generative models has led to the creation of incredibly realistic synthetic images that are becoming increasingly difficult to distinguish from real-world data. The widespread use of Variational Models, Diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Anant Mehta , Bryant McArthur , Nagarjuna Kolloju , Zhengzhong Tu

Using a deep neural network, we demonstrate a digital staining technique, which we term PhaseStain, to transform quantitative phase images (QPI) of labelfree tissue sections into images that are equivalent to brightfield microscopy images…

Image and Video Processing · Electrical Eng. & Systems 2019-02-08 Yair Rivenson , Tairan Liu , Zhensong Wei , Yibo Zhang , Aydogan Ozcan

Pathologists have a rich vocabulary with which they can describe all the nuances of cellular morphology. In their world, there is a natural pairing of images and words. Recent advances demonstrate that machine learning models can now be…

Machine Learning · Computer Science 2022-07-14 Simon M. Thomas , James G. Lefevre , Glenn Baxter , Nicholas A. Hamilton

Immunohistochemical (IHC) staining serves as a valuable technique for detecting specific antigens or proteins through antibody-mediated visualization. However, the IHC staining process is both time-consuming and costly. To address these…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Zetong Chen , Yuzhuo Chen , Hai Zhong , Xu Qiao

In this paper, we develop a complete pipeline for stain normalization, segmentation, and classification of nuclei in hematoxylin and eosin (H&E) stained breast cancer histopathology images. In the first step, we use a CNN-based stain…

Computer Vision and Pattern Recognition · Computer Science 2018-11-12 Edwin Yuan , Junkyo Suh

Generative Adversarial Networks (GANs) have been successfully used to synthesize realistically looking images of faces, scenery and even medical images. Unfortunately, they usually require large training datasets, which are often scarce in…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Christoph Baur , Shadi Albarqouni , Nassir Navab

Synthetic images can be used for the development and evaluation of deep learning algorithms in the context of limited availability of data. In the field of computational pathology, where histology images are large in size and visual context…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Srijay Deshpande , Fayyaz Minhas , Simon Graham , Nasir Rajpoot

Integration of quantum computing in generative machine learning models has the potential to offer benefits such as training speed-up and superior feature extraction. However, the existing quantum generative adversarial networks (QGANs) fail…

Quantum Physics · Physics 2025-05-15 Amena Khatun , Kübra Yeter Aydeniz , Yaakov S. Weinstein , Muhammad Usman

We introduce a new AI-ready computational pathology dataset containing restained and co-registered digitized images from eight head-and-neck squamous cell carcinoma patients. Specifically, the same tumor sections were stained with the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-29 Parmida Ghahremani , Joseph Marino , Juan Hernandez-Prera , Janis V. de la Iglesia , Robbert JC Slebos , Christine H. Chung , Saad Nadeem
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