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Large-scale pretraining followed by task-specific finetuning has achieved great success in various NLP tasks. Since finetuning all parameters of large pretrained models poses substantial computational and memory challenges, several…

Computation and Language · Computer Science 2024-03-19 Ruiyi Zhang , Rushi Qiang , Sai Ashish Somayajula , Pengtao Xie

Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Shuo Jiang , Zhuwen Chen , Liaoman Xu , Yanming Zhu , Changmiao Wang , Jiong Zhang , Feiwei Qin , Yifei Chen , Zhu Zhu

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Unsupervised domain adaptation (UDA) methods have been broadly utilized to improve the models' adaptation ability in general computer vision. However, different from the natural images, there exist huge semantic gaps for the nuclei from…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Canran Li , Dongnan Liu , Haoran Li , Zheng Zhang , Guangming Lu , Xiaojun Chang , Weidong Cai

Breast cancer is the most commonly diagnosed cancer worldwide, with over two million new cases each year. During diagnostic tumour grading, pathologists manually count the number of dividing cells (mitotic figures) in biopsy or tumour…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Jack Breen , Kieran Zucker , Nicolas M. Orsi , Nishant Ravikumar

In medical contexts, the imbalanced data distribution in long-tailed datasets, due to scarce labels for rare diseases, greatly impairs the diagnostic accuracy of deep learning models. Recent multimodal text-image supervised foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Sirui Li , Li Lin , Yijin Huang , Pujin Cheng , Xiaoying Tang

Fine-tuning pre-trained large language models in a parameter-efficient manner is widely studied for its effectiveness and efficiency. LoRA is one of the most widely used methods, which assumes that the optimization process is essentially…

Computation and Language · Computer Science 2024-12-16 Changqun Li , Chaofan Ding , Kexin Luan , Xinhan Di

Emerging 3D geometric foundation models, such as DUSt3R, offer a promising approach for in-the-wild 3D vision tasks. However, due to the high-dimensional nature of the problem space and scarcity of high-quality 3D data, these pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Ziqi Lu , Heng Yang , Danfei Xu , Boyi Li , Boris Ivanovic , Marco Pavone , Yue Wang

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Most tumor grading systems for human as for veterinary histopathology are based upon the absolute count of mitotic figures in a certain reference area of a histology slide. Since time for prognostication is limited in a diagnostic setting,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Marc Aubreville , Christof A. Bertram , Robert Klopfleisch , Andreas Maier

Although vision foundation models (VFMs) are increasingly reused for biomedical image analysis, it remains unclear whether the latent representations they provide are general enough to support effective transfer and reuse across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Caterina Fuster-Barceló , Virginie Uhlmann

Using massive datasets, foundation models are large-scale, pre-trained models that perform a wide range of tasks. These models have shown consistently improved results with the introduction of new methods. It is crucial to analyze how these…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Mobina Mansoori , Sajjad Shahabodini , Farnoush Bayatmakou , Jamshid Abouei , Konstantinos N. Plataniotis , Arash Mohammadi

Atypical mitotic figures (AMFs) represent abnormal cell division associated with poor prognosis. Yet their detection remains difficult due to low prevalence, subtle morphology, and inter-observer variability. The MIDOG 2025 challenge…

Image and Video Processing · Electrical Eng. & Systems 2025-10-15 Guillaume Balezo , Hana Feki , Raphaël Bourgade , Lily Monnier , Matthieu Blons , Alice Blondel , Etienne Decencière , Albert Pla Planas , Thomas Walter

Accurate lung tumor segmentation is crucial for improving diagnosis, treatment planning, and patient outcomes in oncology. However, the complexity of tumor morphology, size, and location poses significant challenges for automated…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Elena Mulero Ayllón , Massimiliano Mantegna , Linlin Shen , Paolo Soda , Valerio Guarrasi , Matteo Tortora

Mitotic figures (MFs) are relevant biomarkers in tumor grading. Differentiating atypical MFs (AMFs) from normal MFs (NMFs) remains difficult, as manual annotation is time-consuming and subjective. In this work an ensemble of ConvNeXtBase…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Sara Krauss , Ellena Spieß , Daniel Hieber , Frank Kramer , Johannes Schobel , Dominik Müller

Histopathological prognostication of neoplasia including most tumor grading systems are based upon a number of criteria. Probably the most important is the number of mitotic figures which are most commonly determined as the mitotic count…

Computer Vision and Pattern Recognition · Computer Science 2020-01-06 Marc Aubreville , Christof A. Bertram , Robert Klopfleisch , Andreas Maier

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…

Computer Vision and Pattern Recognition · Computer Science 2022-02-18 Robin Elizabeth Yancey

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Wessam M. Salama , Ahmed Shokry

Automated detection of mitotic figures in histopathology images has seen vast improvements, thanks to modern deep learning-based pipelines. Application of these methods, however, is in practice limited by strong variability of images…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Marc Aubreville , Christof Bertram , Mitko Veta , Robert Klopfleisch , Nikolas Stathonikos , Katharina Breininger , Natalie ter Hoeve , Francesco Ciompi , Andreas Maier
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