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Foundation models trained via vision-language pretraining have demonstrated strong zero-shot capabilities across diverse image domains, yet their application to volumetric medical imaging remains limited. We introduce MedCT-VLM: Medical CT…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Thuraya Alzubaidi , Farhad R. Nezami , Muzammil Behzad

Low-Rank Adaptation (LoRA) enables parameter-efficient fine-tuning of large models by decomposing weight updates into low-rank matrices, significantly reducing storage and computational overhead. While effective, standard LoRA lacks…

Machine Learning · Computer Science 2026-05-11 Viktar Dubovik , Patryk Marszałek , Jacek Tabor , Tomasz Kuśmierczyk

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Domain shift presents a significant challenge in applying Deep Learning to the segmentation of 3D medical images from sources like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). Although numerous Domain Adaptation methods…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Boris Shirokikh , Anvar Kurmukov , Mariia Donskova , Valentin Samokhin , Mikhail Belyaev , Ivan Oseledets

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Claudio Fernandez-Martín , Umay Kiraz , Julio Silva-Rodríguez , Sandra Morales , Emiel Janssen , Valery Naranjo

Digitization of histopathology slides has led to several advances, from easy data sharing and collaborations to the development of digital diagnostic tools. Deep learning (DL) methods for classification and detection have shown great…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Apostolia Tsirikoglou , Karin Stacke , Gabriel Eilertsen , Martin Lindvall , Jonas Unger

Foundation models have revolutionized AI, but adapting them efficiently for multimodal tasks, particularly in dual-stream architectures composed of unimodal encoders, such as DINO and BERT, remains a significant challenge.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Wish Suharitdamrong , Tony Alex , Muhammad Awais , Sara Ahmed

Task-specific deep learning models in histopathology offer promising opportunities for improving diagnosis, clinical research, and precision medicine. However, development of such models is often limited by availability of high-quality…

PURPOSE: Deep learning methods for classifying prostate cancer (PCa) in ultrasound images typically employ convolutional networks (CNNs) to detect cancer in small regions of interest (ROI) along a needle trace region. However, this approach…

Despite the promise of computational pathology foundation models, adapting them to specific clinical tasks remains challenging due to the complexity of whole-slide image (WSI) processing, the opacity of learned features, and the wide range…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdul Rahman Diab , Emily E. Karn , Renchin Wu , Emily S. Ruiz , William Lotter

We propose a new training scheme for domain generalization in mitotic figure detection. Mitotic figures show different characteristics for each scanner. We consider each scanner as a 'domain' and the image distribution specified for each…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Youjin Chung , Jihoon Cho , Jinah Park

Fine-tuning adapts a pre-trained model to downstream tasks using a small amount of labeled data. Low-Rank Adaptation (LoRA) is an efficient fine-tuning method that reduces memory and computation costs while often achieving performance close…

Machine Learning · Computer Science 2026-05-20 Ali Zindari , Rotem Mulayoff , Sebastian U. Stich

Low-Rank Adaptation (LoRA) has emerged as a widely adopted parameter-efficient fine-tuning (PEFT) technique for foundation models. Recent work has highlighted an inherent asymmetry in the initialization of LoRA's low-rank factors, which has…

Machine Learning · Statistics 2025-06-18 Anastasis Kratsios , Tin Sum Cheng , Aurelien Lucchi , Haitz Sáez de Ocáriz Borde

The growing demand for accurate and equitable AI models in digital dermatology faces a significant challenge: the lack of diverse, high-quality labeled data. In this work, we investigate the potential of domain-specific foundation models…

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

The Segment Anything Model (SAM) has demonstrated remarkable capabilities of scaled-up segmentation models, enabling zero-shot generalization across a variety of domains. By leveraging large-scale foundational models as pre-trained models,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Weijia Feng , Lingting Zhu , Lequan Yu

While Low-Rank Adaptation (LoRA) has proven beneficial for efficiently fine-tuning large models, LoRA fine-tuned text-to-image diffusion models lack diversity in the generated images, as the model tends to copy data from the observed…

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