English
Related papers

Related papers: CellForge: Agentic Design of Virtual Cell Models

200 papers

The emergence of LLMs has catalyzed a paradigm shift in autonomous agent development, enabling systems capable of reasoning, planning, and executing complex multi-step tasks. However, existing agent frameworks often suffer from…

Artificial Intelligence · Computer Science 2026-01-21 Akbar Anbar Jafari , Cagri Ozcinar , Gholamreza Anbarjafari

The emergence of large language models has catalyzed two distinct yet interconnected paradigms in artificial intelligence: standalone AI Agents and collaborative Agentic AI ecosystems. This comprehensive study establishes a definitive…

Artificial Intelligence · Computer Science 2025-06-17 Prashik Buddhaghosh Bansod

Cellular Agent-Based Models are commonly employed to describe a variety biological systems. Over the course of the past years, many modeling tools have emerged which solve particular research questions. In this short opinion piece, we argue…

Cell Behavior · Quantitative Biology 2025-11-18 Jonas Pleyer

The automation of scientific discovery represents a critical milestone in Artificial Intelligence (AI) research. However, existing agentic systems for science suffer from two fundamental limitations: rigid, pre-programmed workflows that…

Artificial Intelligence · Computer Science 2025-10-20 Ed Li , Junyu Ren , Xintian Pan , Cat Yan , Chuanhao Li , Dirk Bergemann , Zhuoran Yang

Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation of various tools to achieve desired outcomes can be…

Artificial Intelligence · Computer Science 2024-07-16 Yihang Xiao , Jinyi Liu , Yan Zheng , Xiaohan Xie , Jianye Hao , Mingzhi Li , Ruitao Wang , Fei Ni , Yuxiao Li , Jintian Luo , Shaoqing Jiao , Jiajie Peng

GPU kernels are critical for ML performance but difficult to optimize across diverse accelerators. We present KForge, a platform-agnostic framework built on two collaborative LLM-based agents: a generation agent that produces and…

Machine Learning · Computer Science 2025-11-18 Taras Sereda , Tom St. John , Burak Bartan , Natalie Serrino , Sachin Katti , Zain Asgar

Multi-agent workflows have become an effective strategy for tackling complicated tasks by decomposing them into multiple sub-tasks and assigning them to specialized agents. However, designing optimal workflows remains challenging due to the…

Human-Computer Interaction · Computer Science 2025-07-22 Pan Hao , Dongyeop Kang , Nicholas Hinds , Qianwen Wang

Literature on the modeling and simulation of complex adaptive systems (cas) has primarily advanced vertically in different scientific domains with scientists developing a variety of domain-specific approaches and applications. However,…

Multiagent Systems · Computer Science 2017-08-09 Muaz A. Niazi

Foundation model-enabled generative artificial intelligence facilitates the development and implementation of agents, which can leverage distinguished reasoning and language processing capabilities to takes a proactive, autonomous role to…

Artificial Intelligence · Computer Science 2024-11-07 Yue Liu , Sin Kit Lo , Qinghua Lu , Liming Zhu , Dehai Zhao , Xiwei Xu , Stefan Harrer , Jon Whittle

Agent-based modeling and network science have been used extensively to advance our understanding of emergent collective behavior in systems that are composed of a large number of simple interacting individuals or agents. With the increasing…

Multiagent Systems · Computer Science 2019-03-14 Marcos Cardinot , Colm O'Riordan , Josephine Griffith , Matjaž Perc

Autonomous AI is no longer a hard-to-reach concept, it enables the agents to move beyond executing tasks to independently addressing complex problems, adapting to change while handling the uncertainty of the environment. However, what makes…

Neurons and Cognition · Quantitative Biology 2025-05-12 Zinan Liu , Haoran Li , Jingyi Lu , Gaoyuan Ma , Xu Hong , Giovanni Iacca , Arvind Kumar , Shaojun Tang , Lin Wang

Developing a reinforcement learning (RL) agent often involves identifying values for numerous parameters, covering the policy, reward function, environment, and agent-internal architecture. Since these parameters are interrelated in complex…

Machine Learning · Computer Science 2025-04-03 Francisco Erivaldo Fernandes Junior , Antti Oulasvirta

Recent significant advances in integrating multiple Large Language Model (LLM) systems have enabled Agentic Frameworks capable of performing complex tasks autonomously, including novel scientific research. We develop and demonstrate such a…

Artificial Intelligence · Computer Science 2025-07-16 Darui Lu , Jordan M. Malof , Willie J. Padilla

The rise of multi-agent systems powered by large language models (LLMs) and specialized reasoning agents exposes fundamental limitations in today's data management architectures. Traditional databases and data fabrics were designed for…

Multiagent Systems · Computer Science 2025-12-11 Ioana Giurgiu , Michael E. Nidd

Large language models generate plausible code but cannot verify correctness. Existing multi-agent systems simulate execution or leave verification optional. We introduce execution-grounded verification as a first-class principle: every code…

Software Engineering · Computer Science 2026-04-16 Rajesh Kumar , Waqar Ali , Junaid Ahmed , Najma Imtiaz Ali , Shaban Usman

In an era where vast amounts of data are collected and processed from diverse sources, there is a growing demand for sophisticated AI systems capable of intelligently fusing and analyzing this information. To address these challenges,…

Software Engineering · Computer Science 2025-11-24 Amine Ben Hassouna , Hana Chaari , Ines Belhaj

The emergence of Agentic AI systems has outpaced the architectural thinking required to operate them effectively. These agents differ fundamentally from traditional software: their behavior is not fixed at deployment but continuously shaped…

Software Engineering · Computer Science 2026-01-13 Shaunak Biswas , Hiya Bhatt , Karthik Vaidhyanathan

We envision the Full-Body AI Agent as a comprehensive AI system designed to simulate, analyze, and optimize the dynamic processes of the human body across multiple biological levels. By integrating computational models, machine learning…

Tissues and Organs · Quantitative Biology 2025-08-28 Aoqi Wang , Jiajia Liu , Jianguo Wen , Yangyang Luo , Zhiwei Fan , Liren Yang , Xi Hu , Ruihan Luo , Yankai Yu , Sophia Li , Weiling Zhao , Xiaobo Zhou

Leveraging multiple Large Language Models(LLMs) has proven effective for addressing complex, high-dimensional tasks, but current approaches often rely on static, manually engineered multi-agent configurations. To overcome these constraints,…

Machine Learning · Computer Science 2025-07-21 Xiaowen Ma , Chenyang Lin , Yao Zhang , Volker Tresp , Yunpu Ma

Agent-based modeling is a computational dynamic modeling technique that may be less familiar to some readers. Agent-based modeling seeks to understand the behaviour of complex systems by situating agents in an environment and studying the…

Multiagent Systems · Computer Science 2023-04-19 G. Wade McDonald , Nathaniel D. Osgood
‹ Prev 1 2 3 10 Next ›