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As software systems grow in scale and complexity, vulnerability management is increasingly strained by high alert volumes, fragmented toolchains, and manual triage processes. We introduce AgenticVM, a multi-agent framework that integrates…

Cryptography and Security · Computer Science 2026-05-05 Asrul Arifin , Hussain Ahmad , Yiyao Zhang , Diksha Goel

Inertial fusion energy promises nearly unlimited, clean power if it can be achieved. However, the design and engineering of fusion systems requires controlling and manipulating matter at extreme energies and timescales; the shock physics…

Designing and evaluating personalized and proactive assistant agents remains challenging due to the time, cost, and ethical concerns associated with human-in-the-loop experimentation. Existing Human-Computer Interaction (HCI) methods often…

Human-Computer Interaction · Computer Science 2025-11-25 Ziyi Xuan , Yiwen Wu , Xuhai Xu , Vinod Namboodiri , Mooi Choo Chuah , Yu Yang

The traditional ML development methodology does not enable a large number of contributors, each with distinct objectives, to work collectively on the creation and extension of a shared intelligent system. Enabling such a collaborative…

Machine Learning · Computer Science 2023-01-02 Andrea Gesmundo

Advances in large language models (LLMs) have recently opened new and promising avenues for small-molecule drug discovery. Yet existing LLM-based approaches for molecular generation often suffer from high rates of invalid and low-quality…

Machine Learning · Computer Science 2026-05-15 Andrew Y. Zhou , Sharvaree Vadgama , Sumanth Varambally , Peter Eckmann , Michael K. Gilson , Rose Yu

Software testing has progressed toward intelligent automation, yet current AI-based test generators still suffer from static, single-shot outputs that frequently produce invalid, redundant, or non-executable tests due to the lack of…

Software Engineering · Computer Science 2026-01-07 Saba Naqvi , Mohammad Baqar , Nawaz Ali Mohammad

Large language models (LLMs) have made rapid advancements in code generation for popular languages such as Python and C++. Many of these recent gains can be attributed to the use of ``agents'' that wrap domain-relevant tools alongside LLMs.…

Hardware Architecture · Computer Science 2026-03-31 Patrick Yubeaton , Siddharth Garg , Chinmay Hegde

LLM-based autonomous agents have demonstrated strong capabilities in reasoning, planning, and tool use, yet remain limited when tasks require sustained coordination across roles, tools, and environments. Multi-agent systems address this…

The field of Artificial Intelligence is undergoing a transition from Generative AI -- probabilistic generation of text and images -- to Agentic AI, in which autonomous systems execute actions within external environments on behalf of users.…

Artificial Intelligence · Computer Science 2026-03-02 Sheng Cao , Zhao Chang , Chang Li , Hannan Li , Liyao Fu , Ji Tang

The discovery of novel small molecule drugs remains a critical scientific challenge with far-reaching implications for treating diseases and advancing human health. Traditional drug development--especially for small molecule…

Biomolecules · Quantitative Biology 2025-04-01 Bowen Gao , Yanwen Huang , Yiqiao Liu , Wenxuan Xie , Wei-Ying Ma , Ya-Qin Zhang , Yanyan Lan

Large language models are increasingly deployed as multi-agent systems, where specialized roles communicate and collaborate through structured interactions to solve complex tasks that often exceed the capacity of a single agent. However,…

Computation and Language · Computer Science 2026-01-28 Yimeng Wang , Jiaxing Zhao , Hongbin Xie , Hexing Ma , Yuzhen Lei , Shuangxue Liu , Xuan Song , Zichen Zhang , Haoran Zhang

Metasurface inverse design has become central to realizing complex optical functionality, yet translating target responses into executable, solver-compatible workflows still demands specialized expertise in computational electromagnetics…

Artificial Intelligence · Computer Science 2026-04-03 Yi Huang , Bowen Zheng , Yunxi Dong , Hong Tang , Huan Zhao , S. M. Rakibul Hasan Shawon , Hualiang Zhang

Large Intelligent Systems are so complex these days that an urgent need for designing such systems in best available way is evolving. Modeling is the useful technique to show a complex real world system into the form of abstraction, so that…

Software Engineering · Computer Science 2011-11-04 Ankit Chaudhary , Jagdish L. Raheja

Rapid advances in Large Language Models (LLMs) create new opportunities by enabling efficient exploration of broad, complex design spaces. This is particularly valuable in computer architecture, where performance depends on…

Artificial Intelligence · Computer Science 2026-04-29 Alexander Blasberg , Vasilis Kypriotis , Dimitrios Skarlatos

Metamaterials, renowned for their exceptional mechanical, electromagnetic, and thermal properties, hold transformative potential across diverse applications, yet their design remains constrained by labor-intensive trial-and-error methods…

Multi-agent large language model frameworks are promising for complex multi step reasoning, yet existing systems remain weak for scientific and knowledge intensive domains due to static prompts and agent roles, rigid workflows, and…

Artificial Intelligence · Computer Science 2026-03-04 Yichao Feng , Haoran Luo , Zhenghong Lin , Yiqun Sun , Pengfei Wei , Lawrence B. Hsieh , Anh Tuan Luu

Techniques for coordination of multi-agent systems are vast and varied, often utilizing purpose-built solvers or controllers with tight coupling to the types of systems involved or the coordination goal. In this paper, we introduce a…

Optimization and Control · Mathematics 2025-04-07 Tyler Hanks , Hans Riess , Samuel Cohen , Trevor Gross , Matthew Hale , James Fairbanks

Training AI models has always been challenging, especially when there is a need for custom models to provide personalized services. Algorithm engineers often face a lengthy process to iteratively develop models tailored to specific business…

Artificial Intelligence · Computer Science 2023-11-27 Haoyuan Li , Hao Jiang , Tianke Zhang , Zhelun Yu , Aoxiong Yin , Hao Cheng , Siming Fu , Yuhao Zhang , Wanggui He

Large language models (LLMs) are transforming cellular biology by enabling the development of "virtual cells"--computational systems that represent, predict, and reason about cellular states and behaviors. This work provides a comprehensive…

Computation and Language · Computer Science 2025-10-10 Krinos Li , Xianglu Xiao , Shenglong Deng , Lucas He , Zijun Zhong , Yuanjie Zou , Zhonghao Zhan , Zheng Hui , Weiye Bao , Guang Yang

This paper introduces a multi-agent framework guided by Large Language Models (LLMs) to assist in the early stages of engineering design, a phase often characterized by vast parameter spaces and inherent uncertainty. Operating under a…

Artificial Intelligence · Computer Science 2026-04-21 Varun Kumar , George Em Karniadakis
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