English
Related papers

Related papers: CellForge: Agentic Design of Virtual Cell Models

200 papers

Affective computing has made significant strides in emotion recognition and generation, yet current approaches mainly focus on short-term pattern recognition and lack a comprehensive framework to guide affective agents toward long-term…

Human-Computer Interaction · Computer Science 2025-02-26 Bin Yin , Chong-Yi Liu , Liya Fu , Jinkun Zhang

Agent-based modeling is a paradigm of modeling dynamic systems of interacting agents that are individually governed by specified behavioral rules. Training a model of such agents to produce an emergent behavior by specification of the…

Machine Learning · Computer Science 2019-10-11 Karan K. Budhraja , Hang Gao , Tim Oates

Agent-based modeling is indispensable for studying complex systems across many domains. However, existing simulation platforms exhibit two major issues: performance and modularity. Low performance prevents simulations with a large number of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-17 Lukas Johannes Breitwieser

A cell can be seen as an adaptive autonomous agent or as a society of adaptive autonomous agents, where each can exhibit a particular behaviour depending on its cognitive capabilities. We present an intracellular signalling model obtained…

Multiagent Systems · Computer Science 2007-05-23 Pedro Pablo Gonzalez Perez , Maura Cardenas Garcia , Carlos Gershenson , Jaime Lagunez-Otero

The paper presents a detailed Agentic Artificial Intelligence (AI) model that would enable people with disabilities and neurodivergence to lead healthier lives and have more regular days. The system will use a multi-layer structure; it will…

Artificial Intelligence · Computer Science 2025-12-01 Salman Jan , Toqeer Ali Syed , Gohar Ali , Ali Akarma , Mohammad Riyaz Belgaum , Ahmad Ali

Cybersecurity decision-making increasingly occurs in environments characterized by uncertainty, partial observability, and adversarial manipulation, where heterogeneous signals from multiple sources are often incomplete, ambiguous, or…

Cryptography and Security · Computer Science 2026-05-01 Andrei Kojukhov , Arkady Bovshover

Large language models (LLMs) have recently gained significant attention as a promising approach to accelerate scientific discovery. However, their application in open-ended scientific domains such as biology remains limited, primarily due…

Machine Learning · Computer Science 2026-05-21 Yunhui Jang , Lu Zhu , Jake Fawkes , Alisandra Kaye Denton , Dominique Beaini , Emmanuel Noutahi

The development of artificial intelligence systems is transitioning from creating static, task-specific models to dynamic, agent-based systems capable of performing well in a wide range of applications. We propose an Interactive Agent…

Agentic methods have emerged as a powerful and autonomous paradigm that enhances reasoning, collaboration, and adaptive control, enabling systems to coordinate and independently solve complex tasks. We extend this paradigm to safety…

Artificial Intelligence · Computer Science 2025-10-30 Juan Ren , Mark Dras , Usman Naseem

Designing realistic and adaptive networked threat scenarios remains a core challenge in cybersecurity research and training, still requiring substantial manual effort. While large language models (LLMs) show promise for automated synthesis,…

Cryptography and Security · Computer Science 2025-10-30 Ana M. Rodriguez , Jaime Acosta , Anantaa Kotal , Aritran Piplai

Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce…

Artificial Intelligence · Computer Science 2025-07-25 Soorya Ram Shimgekar , Shayan Vassef , Abhay Goyal , Navin Kumar , Koustuv Saha

Risk management resulting from the actions and states of the different elements making up a operating room is a major concern during a surgical procedure. Agent-based simulation shows an interest through its interaction concepts,…

Artificial Intelligence · Computer Science 2020-07-23 Bruno Perez , Julien Henriet , Christophe Lang , Laurent Philippe

Using multiple agents was found to improve the debugging capabilities of Large Language Models. However, increasing the number of LLM-agents has several drawbacks such as increasing the running costs and rising the risk for the agents to…

Software Engineering · Computer Science 2025-04-28 Yacine Majdoub , Eya Ben Charrada , Haifa Touati

Agentic AI marks an important transition from single-step generative models to systems capable of reasoning, planning, acting, and adapting over long-lasting tasks. By integrating memory, tool use, and iterative decision cycles, these…

Cryptography and Security · Computer Science 2026-01-12 Sahaya Jestus Lazer , Kshitiz Aryal , Maanak Gupta , Elisa Bertino

Multi-agent systems (MAS) are foundational in simulating complex real-world scenarios involving autonomous, interacting entities. However, traditional MAS architectures often suffer from rigid coordination mechanisms and difficulty adapting…

Multiagent Systems · Computer Science 2026-04-21 Kushagra Agrawal , Nisharg Nargund

Multi-agent systems often operate under feedback, adaptation, and non-stationarity, yet many simulation studies retain static decision rules and fixed control parameters. This paper introduces a general adaptive multi-agent learning…

Multiagent Systems · Computer Science 2025-11-26 Roberto Garrone

Human-like Agents with diverse and dynamic personalities could serve as an essential design probe in the process of user-centered design, thereby enabling designers to enhance the user experience of interactive applications. In this…

Human-Computer Interaction · Computer Science 2024-06-18 Jiale Li , Jiayang Li , Jiahao Chen , Yifan Li , Shijie Wang , Hugo Zhou , Minjun Ye , Yunsheng Su

Building effective clinical decision support systems requires the synthesis of complex heterogeneous multimodal data. Such modalities include temporal electronic health records data, medical images, radiology reports, and clinical notes.…

Artificial Intelligence · Computer Science 2026-05-12 Baraa Al Jorf , Farah E. Shamout

Modern agentic frameworks (e.g., CrewAI and AutoGen) have evolved into complex, autonomous multi-agent systems, introducing unique reliability challenges beyond earlier pipeline-based LLM libraries. However, existing empirical studies focus…

Software Engineering · Computer Science 2026-04-13 Xiaowen Zhang , Hannuo Zhang , Shin Hwei Tan

With the development of foundation model (FM), agentic AI systems are getting more attention, yet their inherent issues like hallucination and poor reasoning, coupled with the frequent ad-hoc nature of system design, lead to unreliable and…

Artificial Intelligence · Computer Science 2026-01-28 Minh-Dung Dao , Quy Minh Le , Hoang Thanh Lam , Duc-Trong Le , Quoc-Viet Pham , Barry O'Sullivan , Hoang D. Nguyen