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Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to…

The emergence of deep learning networks raises a need for explainable AI so that users and domain experts can be confident applying them to high-risk decisions. In this paper, we leverage data from the latent space induced by deep learning…

Machine Learning · Computer Science 2019-09-10 Alan H. Gee , Diego Garcia-Olano , Joydeep Ghosh , David Paydarfar

The ability to interpret machine learning model decisions is critical in such domains as healthcare, where trust in model predictions is as important as their accuracy. Inspired by the development of prototype parts-based deep neural…

Machine Learning · Computer Science 2026-03-06 Jacek Karolczak , Jerzy Stefanowski

Remote screening of respiratory diseases has been widely studied as a non-invasive and early instrument for diagnosis purposes, especially in the pandemic. The respiratory sound classification task has been realized with numerous deep…

Sound · Computer Science 2022-02-08 Zhao Ren , Thanh Tam Nguyen , Wolfgang Nejdl

The use of deep neural models for diagnosis prediction from clinical text has shown promising results. However, in clinical practice such models must not only be accurate, but provide doctors with interpretable and helpful results. We…

In time-series domains where both predictive performance and interpretability are essential, deep neural networks achieve strong results but provide limited insight into how their predictions are made. Projection-based prototype networks…

Machine Learning · Computer Science 2026-05-11 Steven Song , Sahil Sethi , Brett Beaulieu-Jones , Robert L. Grossman

Deep learning models have achieved high performance in medical applications, however, their adoption in clinical practice is hindered due to their black-box nature. Self-explainable models, like prototype-based models, can be especially…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Shreyasi Pathak , Jörg Schlötterer , Jeroen Veltman , Jeroen Geerdink , Maurice van Keulen , Christin Seifert

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

Deep learning methods are powerful tools in classifying multivariate time series data. Despite their high performance, these methods are hard to interpret, which diminishes their applications in high-risk domains such as healthcare. In this…

Machine Learning · Computer Science 2026-05-11 Bhavesh Kalisetti , Vincent Wang , Gaurav R. Ghosal , Maryam Bijanzadeh , Reza Abbasi-Asl

Prototypical part networks offer interpretable alternatives to black-box deep learning models by learning visual prototypes for classification. This work provides a comprehensive analysis of prototype formulations, comparing point-based and…

Machine Learning · Computer Science 2026-01-08 Maximilian Xiling Li , Korbinian Franz Rudolf , Paul Mattes , Nils Blank , Rudolf Lioutikov

We present a deformable prototypical part network (Deformable ProtoPNet), an interpretable image classifier that integrates the power of deep learning and the interpretability of case-based reasoning. This model classifies input images by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Jon Donnelly , Alina Jade Barnett , Chaofan Chen

Recognizing relations between entities is a pivotal task of relational learning. Learning relation representations from distantly-labeled datasets is difficult because of the abundant label noise and complicated expressions in human…

Computation and Language · Computer Science 2021-03-23 Ning Ding , Xiaobin Wang , Yao Fu , Guangwei Xu , Rui Wang , Pengjun Xie , Ying Shen , Fei Huang , Hai-Tao Zheng , Rui Zhang

Interpretability is often an essential requirement in medical imaging. Advanced deep learning methods are required to address this need for explainability and high performance. In this work, we investigate whether additional information…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Luisa Gallee , Meinrad Beer , Michael Goetz

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Deep neural networks have achieved remarkable performance in various text-based tasks but often lack interpretability, making them less suitable for applications where transparency is critical. To address this, we propose ProtoLens, a novel…

Computation and Language · Computer Science 2024-10-25 Bowen Wei , Ziwei Zhu

Prototypical Learning is based on the idea that there is a point (which we call prototype) around which the embeddings of a class are clustered. It has shown promising results in scenarios with little labeled data or to design explainable…

Machine Learning · Computer Science 2024-06-25 Antonio Almudévar , Théo Mariotte , Alfonso Ortega , Marie Tahon , Luis Vicente , Antonio Miguel , Eduardo Lleida

We present PECMAE, an interpretable model for music audio classification based on prototype learning. Our model is based on a previous method, APNet, which jointly learns an autoencoder and a prototypical network. Instead, we propose to…

Classifying images with an interpretable decision-making process is a long-standing problem in computer vision. In recent years, Prototypical Part Networks has gained traction as an approach for self-explainable neural networks, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Zhijie Zhu , Lei Fan , Maurice Pagnucco , Yang Song

The lack of explainability of deep learning models limits the adoption of such models in clinical practice. Prototype-based models can provide inherent explainable predictions, but these have predominantly been designed for classification…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Linde S. Hesse , Nicola K. Dinsdale , Ana I. L. Namburete

Deep learning models have shown high accuracy in classifying electrocardiograms (ECGs), but their black box nature hinders clinical adoption due to a lack of trust and interpretability. To address this, we propose a novel three-stage…

Machine Learning · Computer Science 2025-12-09 Jose Geraldo Fernandes , Luiz Facury de Souza , Pedro Robles Dutenhefner , Gisele L. Pappa , Wagner Meira
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