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Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…

Signal Processing · Electrical Eng. & Systems 2020-12-01 Dani Kiyasseh , Tingting Zhu , David A. Clifton

Prototype-based learning (PbL) using a winner-take-all (WTA) network based on minimum Euclidean distance (ED-WTA) is an intuitive approach to multiclass classification. By constructing meaningful class centers, PbL provides higher…

Machine Learning · Computer Science 2025-01-07 Ramin Zarei Sabzevar , Kamaledin Ghiasi-Shirazi , Ahad Harati

In intensive care units (ICUs), critically ill patients are monitored with electroencephalograms (EEGs) to prevent serious brain injury. The number of patients who can be monitored is constrained by the availability of trained physicians to…

The success of Graph Neural Networks (GNNs) has led to a need for understanding their decision-making process and providing explanations for their predictions, which has given rise to explainable AI (XAI) that offers transparent…

Machine Learning · Computer Science 2024-02-21 Sangwoo Seo , Sungwon Kim , Chanyoung Park

Objective: We investigate whether deep learning techniques for natural language processing (NLP) can be used efficiently for patient phenotyping. Patient phenotyping is a classification task for determining whether a patient has a medical…

Despite recent advances in machine learning and explainable AI, a gap remains in personalized preventive healthcare: predictions, interventions, and recommendations should be both understandable and verifiable for all stakeholders in the…

The analysis of electrocardiogram (ECG) signals can be time consuming as it is performed manually by cardiologists. Therefore, automation through machine learning (ML) classification is being increasingly proposed which would allow ML…

Machine Learning · Computer Science 2022-05-10 Shourya Verma

Early detection of cardiovascular diseases is crucial for effective treatment and an electrocardiogram (ECG) is pivotal for diagnosis. The accuracy of Deep Learning based methods for ECG signal classification has progressed in recent years…

Signal Processing · Electrical Eng. & Systems 2022-04-12 Likith Reddy , Vivek Talwar , Shanmukh Alle , Raju. S. Bapi , U. Deva Priyakumar

Part-prototype Networks (ProtoPNets) are concept-based classifiers designed to achieve the same performance as black-box models without compromising transparency. ProtoPNets compute predictions based on similarity to class-specific…

Machine Learning · Computer Science 2023-01-24 Andrea Bontempelli , Stefano Teso , Katya Tentori , Fausto Giunchiglia , Andrea Passerini

Prototypical part learning is emerging as a promising approach for making semantic segmentation interpretable. The model selects real patches seen during training as prototypes and constructs the dense prediction map based on the similarity…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Hugo Porta , Emanuele Dalsasso , Diego Marcos , Devis Tuia

Advances in deep learning (DL) have resulted in impressive accuracy in some medical image classification tasks, but often deep models lack interpretability. The ability of these models to explain their decisions is important for fostering…

Recently, prototype learning has emerged in semi-supervised medical image segmentation and achieved remarkable performance. However, the scarcity of labeled data limits the expressiveness of prototypes in previous methods, potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Lijian Li

Prototypical parts-based models offer a "this looks like that" paradigm for intrinsic interpretability, yet they typically struggle with ImageNet-scale generalization and often require computationally expensive backbone finetuning.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Mikołaj Janusz , Adam Wróbel , Bartosz Zieliński , Dawid Rymarczyk

Deep neural networks are widely used for classification. These deep models often suffer from a lack of interpretability -- they are particularly difficult to understand because of their non-linear nature. As a result, neural networks are…

Artificial Intelligence · Computer Science 2017-11-22 Oscar Li , Hao Liu , Chaofan Chen , Cynthia Rudin

Digital healthcare systems have enabled the collection of mass healthcare data in electronic healthcare records (EHRs), allowing artificial intelligence solutions for various healthcare prediction tasks. However, existing studies often…

Machine Learning · Computer Science 2025-08-27 Zi Cai , Yu Liu , Zhiyao Luo , Tingting Zhu

Due to the recent advances in the area of deep learning, it has been demonstrated that a deep neural network, trained on a huge amount of data, can recognize cardiac arrhythmias better than cardiologists. Moreover, traditionally feature…

Machine Learning · Computer Science 2019-09-16 Milad Salem , Shayan Taheri , Jiann Shiun-Yuan

Models have been proposed to extract temporal patterns from longitudinal electronic health records (EHR) for clinical predictive models. However, the common relations among patients (e.g., receiving the same medical treatments) were rarely…

Applications · Statistics 2019-09-27 Yue Wang , Tong Wu , Yunlong Wang , Gao Wang

When we are faced with challenging image classification tasks, we often explain our reasoning by dissecting the image, and pointing out prototypical aspects of one class or another. The mounting evidence for each of the classes helps us…

Machine Learning · Computer Science 2020-01-01 Chaofan Chen , Oscar Li , Chaofan Tao , Alina Jade Barnett , Jonathan Su , Cynthia Rudin

Ejection fraction (EF) is a crucial metric for assessing cardiac function and diagnosing conditions such as heart failure. Traditionally, EF estimation requires manual tracing and domain expertise, making the process time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yeganeh Ghamary , Victoria Wu , Hooman Vaseli , Christina Luong , Teresa Tsang , Siavash Bigdeli , Purang Abolmaesumi

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh