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A primary goal of computational phenotype research is to conduct medical diagnosis. In hospital, physicians rely on massive clinical data to make diagnosis decisions, among which laboratory tests are one of the most important resources.…

Artificial Intelligence · Computer Science 2017-11-20 Shiyue Zhang , Pengtao Xie , Dong Wang , Eric P. Xing

Intensive Care Unit (ICU) mortality prediction, which estimates a patient's mortality status at discharge using EHRs collected early in an ICU admission, is vital in critical care. For this task, predictive accuracy alone is insufficient;…

Machine Learning · Computer Science 2025-10-15 Qingwen Li , Xiaohang Zhao , Xiao Han , Hailiang Huang , Lanjuan Liu

The prototypical network is a prototype classifier based on meta-learning and is widely used for few-shot learning because it classifies unseen examples by constructing class-specific prototypes without adjusting hyper-parameters during…

Computer Vision and Pattern Recognition · Computer Science 2022-09-16 Mingcheng Hou , Issei Sato

Electrocardiogram (ECG) signal is a common and powerful tool to study heart function and diagnose several abnormal arrhythmias. While there have been remarkable improvements in cardiac arrhythmia classification methods, they still cannot…

Quantitative Methods · Quantitative Biology 2019-03-14 Sajad Mousavi , Fatemeh Afghah , U. Rajendra Acharya

Imaging-derived phenotypes (IDPs) summarize multi-organ physiology but provide only static snapshots of diseases that evolve over time. In contrast, longitudinal electronic health records encode disease trajectories through temporal…

Information Retrieval · Computer Science 2026-05-13 Zian Wang , Lizhen Lan , Guangming Wang , Haosen Zhang , Minxuan Xu , Qing Li , Tianxing He , Mo Yang , Wenyue Mao , Yajing Zhang , Yan Li , Chengyan Wang

In high-stakes settings, Machine Learning models that can provide predictions that are interpretable for humans are crucial. This is even more true with the advent of complex deep learning based models with a huge number of tunable…

Artificial Intelligence · Computer Science 2023-09-21 Merel de Leeuw den Bouter , Javier Lloret Pardo , Zeno Geradts , Marcel Worring

Electrocardiogram (ECG) signals play critical roles in the clinical screening and diagnosis of many types of cardiovascular diseases. Despite deep neural networks that have been greatly facilitated computer-aided diagnosis (CAD) in many…

Machine Learning · Computer Science 2021-05-31 Jingyi Liu , Zhongyu Li , Xiayue Fan , Jintao Yan , Bolin Li , Xuemeng Hu , Qing Xia , Yue Wu

Understanding the spatial architecture of the tumor microenvironment (TME) is critical to advance precision oncology. We present ProteinPNet, a novel framework based on prototypical part networks that discovers TME motifs from spatial…

Machine Learning · Computer Science 2025-12-03 Louis McConnell , Jieran Sun , Theo Maffei , Raphael Gottardo , Marianna Rapsomaniki

Prototype-based classification learning methods are known to be inherently interpretable. However, this paradigm suffers from major limitations compared to deep models, such as lower performance. This led to the development of the so-called…

Machine Learning · Computer Science 2025-04-18 Sascha Saralajew , Ashish Rana , Thomas Villmann , Ammar Shaker

As mobile robots increasingly operate in environments shared with humans, proactively anticipating human motion rather than responding reactively is critical for preempting collisions during close-proximity navigation, while maintaining…

Human-Computer Interaction · Computer Science 2025-11-24 Xiaoshan Zhou , Carol C. Menassa , Vineet R. Kamat

Life science is entering a new era of petabyte-level sequencing data. Converting such big data to biological insights represents a huge challenge for computational analysis. To this end, we developed DeepMetabolism, a biology-guided deep…

Genomics · Quantitative Biology 2017-05-10 Weihua Guo , You Xu , Xueyang Feng

Ear biometrics offer a stable and contactless modality for identity recognition, yet their effectiveness remains limited by the scarcity of annotated data and significant intra-class variability. Existing methods typically extract identity…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Santhoshkumar Peddi , Sadhvik Bathini , Arun Balasubramanian , Monalisa Sarma , Debasis Samanta

We present ProtoConcepts, a method for interpretable image classification combining deep learning and case-based reasoning using prototypical parts. Existing work in prototype-based image classification uses a ``this looks like that''…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Chiyu Ma , Brandon Zhao , Chaofan Chen , Cynthia Rudin

We introduce ProtoSeg, a novel model for interpretable semantic image segmentation, which constructs its predictions using similar patches from the training set. To achieve accuracy comparable to baseline methods, we adapt the mechanism of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Mikołaj Sacha , Dawid Rymarczyk , Łukasz Struski , Jacek Tabor , Bartosz Zieliński

We introduce ProtoPool, an interpretable image classification model with a pool of prototypes shared by the classes. The training is more straightforward than in the existing methods because it does not require the pruning stage. It is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Dawid Rymarczyk , Łukasz Struski , Michał Górszczak , Koryna Lewandowska , Jacek Tabor , Bartosz Zieliński

The proposed framework named IDEAL (Interpretable-by-design DEep learning ALgorithms) recasts the standard supervised classification problem into a function of similarity to a set of prototypes derived from the training data, while taking…

Machine Learning · Computer Science 2023-11-21 Plamen Angelov , Dmitry Kangin , Ziyang Zhang

Recent advances in deep learning have had a methodological and practical impact on brain-computer interface research. Among the various deep network architectures, convolutional neural networks have been well suited for…

Signal Processing · Electrical Eng. & Systems 2020-03-06 Wonjun Ko , Eunjin Jeon , Seungwoo Jeong , Heung-Il Suk

Concept-based machine learning methods have increasingly gained importance due to the growing interest in making neural networks interpretable. However, concept annotations are generally challenging to obtain, making it crucial to leverage…

Machine Learning · Computer Science 2024-11-06 Alba Carballo-Castro , Sonia Laguna , Moritz Vandenhirtz , Julia E. Vogt

Deployments of artificial intelligence in medical diagnostics mandate not just accuracy and efficacy but also trust, emphasizing the need for explainability in machine decisions. The recent trend in automated medical image diagnostics leans…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Ugur Demir , Debesh Jha , Zheyuan Zhang , Elif Keles , Bradley Allen , Aggelos K. Katsaggelos , Ulas Bagci

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

Machine Learning · Computer Science 2023-08-23 Jeong Min Lee , Milos Hauskrecht
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