Related papers: Dominant ionic currents in rabbit ventricular acti…
Contemporary realistic mathematical models of single-cell cardiac electrical excitation are immensely detailed. Model complexity leads to parameter uncertainty, high computational cost and barriers to mechanistic understanding. There is a…
The complexity and size of state-of-the-art cell models have significantly increased in part due to the requirement that these models possess complex cellular functions which are thought--but not necessarily proven--to be important. Modern…
We develop a simple model of ionic current through neuronal membranes as a function of membrane potential and extracellular ion concentration. The model combines a simplified Poisson-Nernst-Planck (PNP) model of ion transport through…
We numerically investigate the role of mechanical stress in modifying the conductivity properties of the cardiac tissue and its impact in computational models for cardiac electromechanics. We follow a theoretical framework recently proposed…
How is reliable physiological function maintained in cells despite considerable variability in the values of key parameters of multiple interacting processes that govern that function? Here we use the classic Hodgkin-Huxley formulation of…
Vascular calcification is implicated as an important factor in major adverse cardiovascular events (MACE), including heart attack and stroke. A controversy remains over how to integrate the diverse forms of vascular calcification into…
The origin of the high leakage current measured in several vertical-type diamond Schottky devices is conjointly investigated by conducting probe atomic force microscopy (CP-AFM) and confocal micro-Raman/Photoluminescence (PL) imaging…
Action potential propagation along the axons and across the dendrites is the foundation of the electrical activity observed in the brain and the rest of the central nervous system. Theoretical and numerical modeling of this action potential…
We present the statistical method to study the interaction between a chosen protein and another molecule (e.g., both being components of lubricin found in synovial fluid) in a water environment. The research is performed on the example of…
The action potential signal of nerve and muscle is produced by voltage sensitive channels that include a specialized device to sense voltage. Gating currents of the voltage sensor are now known to depend on the back-and-forth movements of…
We report a detailed semi-analytical treatment to investigate the dynamics of a single cavity soliton (CS) and two co-propagating CSs separately in a Kerr mediated passive optical fiber resonator which is driven by a phase-modulated pump.…
The noble elements constitute the simplest group of atoms. At low temperatures or high pressures they freeze into the face-centered cubic (fcc) crystal structure (except helium). We perform molecular dynamics using the recently proposed…
We analyze the spectrum of harmonic flow, $v_n(p_T)$ for $n=0\text{--}5$, in event-by-event hydrodynamic simulations of Pb+Pb collisions at the CERN Large Hadron Collider ($\sqrt{s_{NN}}=2.76\,{\text{TeV}}$) with principal component…
A solvable molecular collision model that predicts Aharonov-Bohm (AB) like scattering in the adiabatic approximation is introduced. For it, we propagate coupled channel wave packets without resorting to a Born-Oppenheimer (BO)…
Cardiac diseases are the principal cause of human morbidity and mortality in the western world. The electric potential of the heart is a highly complex signal emerging as a result of nontrivial flow conduction, hierarchical structuring and…
Halide perovskite nanocrystals are leading candidates for next-generation optoelectronics, yet the role of surface ligands in controlling their phonon dynamics remains poorly understood. These dynamics critically govern nonradiative…
We study the phase diagram of strongly interacting matter in the framework of a non-local SU(2) chiral quark model which includes wave function renormalization and coupling to the Polyakov loop. Both non-local interactions based on the…
The successive ionization potentials (IPs) and electron affinities (EAs) for superheavy elements with $111 \leq Z \leq 114$, namely, Rg, Cn, Nh, and Fl are reexamined using the relativistic Fock-space coupled-cluster method with…
Active microparticles in confining potentials manifest complex and intriguing dynamical phenomena, as their activity competes with confinement. The steady-state position distributions of harmonically bound active Brownian particles (HBABPs)…
In this paper, we study magnetized winds described by variable adiabatic index equation of state in Paczy\'{n}ski \& Wiita pseudo-Newtonian potential. We identify the flow solutions with the parameter space of the flow. We also confirm that…