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Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

Large Vision Language Models (LVLMs) have demonstrated remarkable reasoning capabilities over textual and visual inputs. However, these models remain prone to generating misinformation. Identifying and mitigating ungrounded responses is…

Artificial Intelligence · Computer Science 2025-05-07 Gabriela Ben-Melech Stan , Estelle Aflalo , Man Luo , Shachar Rosenman , Tiep Le , Sayak Paul , Shao-Yen Tseng , Vasudev Lal

In recent years, cross-modal reasoning (CMR), the process of understanding and reasoning across different modalities, has emerged as a pivotal area with applications spanning from multimedia analysis to healthcare diagnostics. As the…

Artificial Intelligence · Computer Science 2023-09-15 Dizhan Xue , Shengsheng Qian , Zuyi Zhou , Changsheng Xu

One of the major barriers to using large language models (LLMs) in medicine is the perception they use uninterpretable methods to make clinical decisions that are inherently different from the cognitive processes of clinicians. In this…

Computation and Language · Computer Science 2023-08-15 Thomas Savage , Ashwin Nayak , Robert Gallo , Ekanath Rangan , Jonathan H Chen

Knowledge Tracing (KT) models students' evolving knowledge states to predict future performance, serving as a foundation for personalized education. While traditional deep learning models achieve high accuracy, they often lack…

Computation and Language · Computer Science 2026-03-25 Runze Li , Kedi Chen , Guwei Feng , Mo Yu , Jun Wang , Wei Zhang

Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…

Machine Learning · Computer Science 2019-08-08 Sana Tonekaboni , Shalmali Joshi , Melissa D McCradden , Anna Goldenberg

Knowledge Tracing (KT) infers a student's knowledge state from past interactions to predict future performance. Conventional Deep Learning (DL)-based KT models are typically tied to platform-specific identifiers and latent representations,…

Artificial Intelligence · Computer Science 2026-04-23 Zhiyi Duan , Hongyu Yuan , Rui Liu

Recurrent Neural Networks (RNNs) have achieved remarkable performance on a range of tasks. A key step to further empowering RNN-based approaches is improving their explainability and interpretability. In this work we present MEME: a model…

Machine Learning · Computer Science 2021-04-15 Dmitry Kazhdan , Botty Dimanov , Mateja Jamnik , Pietro Liò

Interpretable machine learning has exploded as an area of interest over the last decade, sparked by the rise of increasingly large datasets and deep neural networks. Simultaneously, large language models (LLMs) have demonstrated remarkable…

Computation and Language · Computer Science 2024-02-06 Chandan Singh , Jeevana Priya Inala , Michel Galley , Rich Caruana , Jianfeng Gao

Multimodal Large Language Models (MLLMs) have shown strong potential for radiology report generation, yet their clinical translation is hindered by architectural heterogeneity and the prevalence of factual hallucinations. Standard…

Machine Learning · Computer Science 2026-01-13 Kun Zhao , Siyuan Dai , Pan Wang , Jifeng Song , Hui Ji , Chenghua Lin , Liang Zhan , Haoteng Tang

Intelligent learning diagnosis is a critical engine of intelligent tutoring systems, which aims to estimate learners' current knowledge mastery status and predict their future learning performance. The significant challenge with traditional…

Artificial Intelligence · Computer Science 2023-06-14 Zhifeng Wang , Wenxing Yan , Chunyan Zeng , Shi Dong

Explainable recommendation has demonstrated significant advantages in informing users about the logic behind recommendations, thereby increasing system transparency, effectiveness, and trustworthiness. To provide personalized and…

Information Retrieval · Computer Science 2025-02-19 Yuhan Li , Xinni Zhang , Linhao Luo , Heng Chang , Yuxiang Ren , Irwin King , Jia Li

Reasoning-oriented large language models (RLMs) achieve strong gains on tasks such as mathematics and coding by generating explicit intermediate reasoning. However, their impact on machine translation (MT) remains underexplored. We…

Computation and Language · Computer Science 2026-02-17 Sara Rajaee , Sebastian Vincent , Alexandre Berard , Marzieh Fadaee , Kelly Marchisio , Tom Kocmi

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Chronic Kidney Disease (CKD) is one of the widespread Chronic diseases with no known ultimo cure and high morbidity. Research demonstrates that progressive Chronic Kidney Disease (CKD) is a heterogeneous disorder that significantly impacts…

Machine Learning · Computer Science 2025-01-28 K M Tawsik Jawad , Anusha Verma , Fathi Amsaad , Lamia Ashraf

While large transformer models excel in predictive performance, their lack of interpretability restricts their usefulness in high-stakes domains. To remedy this, we propose the Generalized Induction-Head Model (GIM), an interpretable model…

Computation and Language · Computer Science 2025-10-31 Eunji Kim , Sriya Mantena , Weiwei Yang , Chandan Singh , Sungroh Yoon , Jianfeng Gao

LLMs for clinical decision support often fail under small but clinically meaningful input shifts such as masking a symptom or negating a finding, despite high performance on static benchmarks. These reasoning failures frequently go…

Machine Learning · Computer Science 2025-07-30 Raj Krishnan Vijayaraj

A patient's estimated glomerular filtration rate (eGFR) can provide important information about disease progression and kidney function. Traditionally, an eGFR time series is interpreted by a human expert labelling it as stable or unstable.…

Machine Learning · Computer Science 2016-05-18 Santosh Tirunagari , Simon Bull , Norman Poh

Interpretable brain network models for disease prediction are of great value for the advancement of neuroscience. GNNs are promising to model complicated network data, but they are prone to overfitting and suffer from poor interpretability,…

Machine Learning · Computer Science 2021-07-13 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang