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Large language models (LLMs) have demonstrated impressive reasoning abilities in complex tasks. However, they lack up-to-date knowledge and experience hallucinations during reasoning, which can lead to incorrect reasoning processes and…

Computation and Language · Computer Science 2024-02-27 Linhao Luo , Yuan-Fang Li , Gholamreza Haffari , Shirui Pan

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Interpretability for machine learning models in medical imaging (MLMI) is an important direction of research. However, there is a general sense of murkiness in what interpretability means. Why does the need for interpretability in MLMI…

Machine Learning · Computer Science 2024-04-17 Alan Q. Wang , Batuhan K. Karaman , Heejong Kim , Jacob Rosenthal , Rachit Saluja , Sean I. Young , Mert R. Sabuncu

Mechanistic interpretability is an emerging diagnostic approach for neural models that has gained traction in broader natural language processing domains. This paradigm aims to provide attribution to components of neural systems where…

Information Retrieval · Computer Science 2025-01-20 Andrew Parry , Catherine Chen , Carsten Eickhoff , Sean MacAvaney

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Large language models (LLMs) face significant token efficiency bottlenecks in code generation and logical reasoning tasks, a challenge that directly impacts inference cost and model interpretability. This paper proposes a formal framework…

Artificial Intelligence · Computer Science 2025-02-03 Lumen AI , Tengzhou No. 1 Middle School , Shihao Ji , Zihui Song , Fucheng Zhong , Jisen Jia , Zhaobo Wu , Zheyi Cao , Tianhao Xu

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Large Language Models (LLMs) are playing an increasingly important role in physics research by assisting with symbolic manipulation, numerical computation, and scientific reasoning. However, ensuring the reliability, transparency, and…

Artificial Intelligence · Computer Science 2025-08-19 Yinggan Xu , Hana Kimlee , Yijia Xiao , Di Luo

Automated mental health prediction using textual data has shown promising results with deep learning and large language models. However, deploying these models in high-stakes real-world settings remains challenging, as existing approaches…

Computation and Language · Computer Science 2026-05-07 Yucheng Ruan , Ling Huang , Qika Lin , Kai He , Mengling Feng

Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions…

Methodology · Statistics 2020-06-25 Simon Kocbek , Primoz Kocbek , Leona Cilar , Gregor Stiglic

Recent large language models (LLMs) have demonstrated remarkable prediction performance for a growing array of tasks. However, their proliferation into high-stakes domains (e.g. medicine) and compute-limited settings has created a…

Artificial Intelligence · Computer Science 2023-12-05 Chandan Singh , Armin Askari , Rich Caruana , Jianfeng Gao

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

With the powerful reasoning capabilities of large language models (LLMs) and vision-language models (VLMs), many recent works have explored using them for decision-making. However, most of these approaches rely solely on language-based…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Yihao Sun , Zhilong Zhang , Yang Yu , Pierre-Luc Bacon

As artificial intelligence systems increasingly operate in Real-world environments, the integration of multi-modal data sources such as vision, language, and audio presents both unprecedented opportunities and critical challenges for…

Machine Learning · Computer Science 2025-07-01 Sree Bhargavi Balija

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Electronic medical records (EMR) contain longitudinal information about patients that can be used to analyze outcomes. Typically, studies on EMR data have worked with established variables that have already been acknowledged to be…

Machine Learning · Computer Science 2017-11-30 Prithwish Chakraborty , Vishrawas Gopalakrishnan , Sharon M. H. Alford , Faisal Farooq

In this study, we present a novel clinical decision support system and discuss its interpretability-related properties. It combines a decision set of rules with a machine learning scheme to offer global and local interpretability. More…

Methodology · Statistics 2021-07-16 Francisco Valente , Simão Paredes , Jorge Henriques

Large language models suffer from knowledge staleness and lack of interpretability due to implicit knowledge storage across entangled network parameters, preventing targeted updates and reasoning transparency. We propose ExplicitLM, a novel…

Artificial Intelligence · Computer Science 2025-11-04 Chengzhang Yu , Zening Lu , Chenyang Zheng , Chiyue Wang , Yiming Zhang , Zhanpeng Jin

Large language models have exhibited impressive performance across a broad range of downstream tasks in natural language processing. However, how a language model predicts the next token and generates content is not generally understandable…