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High-performing medical Large Language Models (LLMs) typically require extensive fine-tuning with substantial computational resources, limiting accessibility for resource-constrained healthcare institutions. This study introduces a…

Computation and Language · Computer Science 2025-10-17 Ziad Elshaer , Essam A. Rashed

Large language models (LLMs) excel at reasoning but struggle with knowledge-intensive questions due to limited context and parametric knowledge. However, existing methods that rely on finetuned LLMs or GNN retrievers are limited by…

Artificial Intelligence · Computer Science 2025-11-07 Yuanning Cui , Zequn Sun , Wei Hu , Zhangjie Fu

The lack of interpretability and transparency are preventing economists from using advanced tools like neural networks in their empirical research. In this paper, we propose a class of interpretable neural network models that can achieve…

Econometrics · Economics 2020-12-01 Yucheng Yang , Zhong Zheng , Weinan E

Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

Machine Learning · Computer Science 2026-03-06 Nishan Mitra

Multimodal fusion benefits disease diagnosis by providing a more comprehensive perspective. Developing algorithms is challenging due to data heterogeneity and the complex within- and between-modality associations. Deep-network-based…

Neurons and Cognition · Quantitative Biology 2020-06-18 Wenxing Hu , Xianghe Meng , Yuntong Bai , Aiying Zhang , Biao Cai , Gemeng Zhang , Tony W. Wilson , Julia M. Stephen , Vince D. Calhoun , Yu-Ping Wang

Accurate interpretation of pediatric dental clinical records and safe antibiotic prescribing remain persistent challenges in dental informatics. Traditional rule-based clinical decision support systems struggle with unstructured dental…

Computation and Language · Computer Science 2025-12-11 Zihan Han , Junyan Ge , Caifeng Li

Recent advances in general medical AI have made significant strides, but existing models often lack the reasoning capabilities needed for complex medical decision-making. This paper presents GMAI-VL-R1, a multimodal medical reasoning model…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Yanzhou Su , Tianbin Li , Jiyao Liu , Chenglong Ma , Junzhi Ning , Cheng Tang , Sibo Ju , Jin Ye , Pengcheng Chen , Ming Hu , Shixiang Tang , Lihao Liu , Bin Fu , Wenqi Shao , Xiaowei Hu , Xiangwen Liao , Yuanfeng Ji , Junjun He

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Current medical language models, adapted from large language models (LLMs), typically predict ICD code-based diagnosis from electronic health records (EHRs) because these labels are readily available. However, ICD codes do not capture the…

Computation and Language · Computer Science 2025-12-09 Wenhao Li , Hongkuan Zhang , Hongwei Zhang , Zhengxu Li , Zengjie Dong , Yafan Chen , Niranjan Bidargaddi , Hong Liu

Medical Large Vision-Language Models (Med-LVLMs) demonstrate significant potential in healthcare, but their reliance on general medical data and coarse-grained global visual understanding limits them in intelligent ophthalmic diagnosis.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Sijing Li , Tianwei Lin , Lingshuai Lin , Wenqiao Zhang , Jiang Liu , Xiaoda Yang , Juncheng Li , Yucheng He , Xiaohui Song , Jun Xiao , Yueting Zhuang , Beng Chin Ooi

Large language models are often assumed to acquire increasingly structured, generalizable internal representations simply by scaling data and parameters. We interrogate this assumption by introducing a Clinical Trial Natural Language…

Artificial Intelligence · Computer Science 2025-08-15 Maël Jullien , Marco Valentino , André Freitas

In spite of the strong performance of machine learning (ML) models in radiology, they have not been widely accepted by radiologists, limiting clinical integration. A key reason is the lack of explainability, which ensures that model…

Human-Computer Interaction · Computer Science 2026-04-14 Sara Ketabi , Matthias W. Wagner , Birgit Betina Ertl-Wagner , Greg A. Jamieson , Farzad Khalvati

Large language models (LLMs) have demonstrated promising performance in generating diagnostic conclusions from imaging findings, thereby supporting radiology reporting, trainee education, and quality control. However, systematic guidance on…

Artificial Intelligence · Computer Science 2026-05-26 Qiuli Wang , Xinhuang Sun , Yonglin Chen , Jie Cheng , Yongxu Liu , Xingpeng Zhang , Xiaoming Li , Wei Chen

In the rapidly evolving field of Explainable Natural Language Processing (NLP), textual explanations, i.e., human-like rationales, are pivotal for explaining model predictions and enriching datasets with interpretable labels. Traditional…

Computation and Language · Computer Science 2025-11-12 Mahdi Dhaini , Juraj Vladika , Ege Erdogan , Zineb Attaoui , Gjergji Kasneci

Accurate molecular property prediction is a critical challenge with wide-ranging applications in chemistry, materials science, and drug discovery. Molecular representation methods, including fingerprints and graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-08-13 Jiaxin Ju , Yizhen Zheng , Huan Yee Koh , Can Wang , Shirui Pan

Interpretability in Graph Convolutional Networks (GCNs) has been explored to some extent in computer vision in general, yet, in the medical domain, it requires further examination. Moreover, most of the interpretability approaches for GCNs,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Anees Kazi , Soroush Farghadani , Nassir Navab

Chest imaging plays an essential role in diagnosing and predicting patients with COVID-19 with evidence of worsening respiratory status. Many deep learning-based approaches for pneumonia recognition have been developed to enable…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Shengchao Chen , Sufen Ren , Guanjun Wang , Mengxing Huang , Chenyang Xue

In the early days of machine learning (ML), the emphasis was on developing complex algorithms to achieve best predictive performance. To understand and explain the model results, one had to rely on post hoc explainability techniques, which…

Machine Learning · Statistics 2023-05-26 Linwei Hu , Vijayan N. Nair , Agus Sudjianto , Aijun Zhang , Jie Chen

Spatio-temporal forecasting plays a crucial role in various sectors such as transportation systems, logistics, and supply chain management. However, existing methods are limited by their ability to handle large, complex datasets. To…

Machine Learning · Computer Science 2024-08-27 Sakhinana Sagar Srinivas , Chidaksh Ravuru , Geethan Sannidhi , Venkataramana Runkana