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Pathologists routinely classify breast tumors according to recurring patterns of nuclear grades, cytoplasmic coloration, and large-scale morphological formations (i.e. streams of spindle cells, adenoid islands, etc.). The fact that there…

Tissues and Organs · Quantitative Biology 2017-04-26 David H. Nguyen

Receiver operating characteristic (ROC) analysis is a tool to evaluate the capacity of a numeric measure to distinguish between groups, often employed in the evaluation of diagnostic tests. Overall classification ability is sometimes…

In machine learning contests such as the ImageNet Large Scale Visual Recognition Challenge and the KDD Cup, contestants can submit candidate solutions and receive from an oracle (typically the organizers of the competition) the accuracy of…

Machine Learning · Computer Science 2015-11-16 Jacob Whitehill

In this paper we obtain an explicit formula for the number of curves in a compact complex surface $X$ (passing through the right number of generic points), that has up to one node and one singularity of codimension $k$, provided the total…

Algebraic Geometry · Mathematics 2015-01-08 Somnath Basu , Ritwik Mukherjee

Let $W(z)$ be a $n\times n$ matrix polynomial with rational coefficients. Denote $C$ the spectral curve $\det \left( w\cdot{\bf 1}-W(z)\right) =0$. Under some natural assumptions about the structure of $W(z)$ we prove that certain…

Algebraic Geometry · Mathematics 2018-07-31 Boris Dubrovin

For a certain class of varieties X, we derive a formula for the valuation d_{X} on the arc space L(Y) of a smooth ambient space Y, in terms of an embedded resolution of singularities. A simple transformation rule yields a formula for the…

Algebraic Geometry · Mathematics 2007-05-23 Johannes Nicaise

For Classical compact Lie groups, we use Macdonald's formula \cite{Ma} and Ricci curvature for analyzing a "concentration locus", which is a tool to detect where a sequence of metric, Borel measurable spaces concentrates its measure.

Group Theory · Mathematics 2022-04-12 Sergio L. Cacciatori , Pietro Ursino

To assess the classification accuracy of a continuous diagnostic result, the receiver operating characteristic (ROC) curve is commonly used in applications. The partial area under the ROC curve (pAUC) is one of widely accepted summary…

Applications · Statistics 2011-03-11 Hung Hung , Chin-Tsang Chiang

2D and 3D tumor features are widely used in a variety of medical image analysis tasks. However, for chemotherapy response prediction, the effectiveness between different kinds of 2D and 3D features are not comprehensively assessed,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Neman Abdoli , Ke Zhang , Patrik Gilley , Xuxin Chen , Youkabed Sadri , Theresa C. Thai , Lauren E. Dockery , Kathleen Moore , Robert S. Mannel , Yuchen Qiu

In clinical practice, multiple biomarkers are used for disease diagnosis, but their individual accuracies are often suboptimal, with only a few proving directly relevant. Effectively selecting and combining biomarkers can significantly…

Methodology · Statistics 2025-09-03 Ao Sun , Zhanwang Deng , Jiahui Zhao , Hang Li , Xiao-Hua Zhou

Let J be the jacobian of a reduced projective curve C with nodes only. 1) We give a simple and natural definition for its many compactifications and show the connection with various other definitions appearing in the literature. 2) Among…

alg-geom · Mathematics 2008-02-03 Valery Alexeev

Functional markers become a more frequent tool in medical diagnosis. In this paper, we aim to define an index allowing to discriminate between populations when the observations are functional data belonging to a Hilbert space. We discuss…

Methodology · Statistics 2025-02-03 Ana M. Bianco , Graciela Boente , Juan Carlos Pardo-Fernández

Breast cancer is the most common malignant tumor among women and the second cause of cancer-related death. Early diagnosis in clinical practice is crucial for timely treatment and prognosis. Dynamic contrast-enhanced magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zixian Li , Yuming Zhong , Yi Wang

A class of generalized conditional gradient algorithms for the solution of optimization problem in spaces of Radon measures is presented. The method iteratively inserts additional Dirac-delta functions and optimizes the corresponding…

Optimization and Control · Mathematics 2021-03-30 Konstantin Pieper , Daniel Walter

Recent work on privacy-preserving machine learning has considered how data-mining competitions such as Kaggle could potentially be "hacked", either intentionally or inadvertently, by using information from an oracle that reports a…

Machine Learning · Computer Science 2017-09-12 Jacob Whitehill

Here we develop some basic analytic tools to study compactness properties of $J$-curves (i.e. pseudo-holomorphic curves) when regarded as submanifolds. Incorporating techniques from the theory of minimal surfaces, we derive an inhomogeneous…

Symplectic Geometry · Mathematics 2010-05-06 Joel W. Fish

We define and count lattice points in the moduli space of stable genus g curves with n labeled points. This extends a construction of the second author for the uncompactified moduli space. The enumeration produces polynomials with top…

Geometric Topology · Mathematics 2014-11-11 Norman Do , Paul Norbury

This is the second in a series of three papers in which we investigate the rational Chow ring of the stack consisting of nodal curves of genus. Here we define the basic classes: the classes of strata and the Mumford classes.

Algebraic Geometry · Mathematics 2009-01-12 Damiano Fulghesu

Lame curves are a particular class of elliptic curves (with a torsion point attached to them) which naturally arise when studying Lame operators with finite monodromy. They can be realized as covers of the projective line unramified outside…

Algebraic Geometry · Mathematics 2007-05-23 Leonardo Zapponi

The area under the ROC curve is widely used as a measure of performance of classification rules. However, it has recently been shown that the measure is fundamentally incoherent, in the sense that it treats the relative severities of…

Methodology · Statistics 2013-08-02 David J. Hand , Christoforos Anagnostopoulos