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Related papers: Pathology-Guided Virtual Staining Metric for Evalu…

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An aesthetics evaluation model is at the heart of predicting users' aesthetic experience and developing user interfaces with higher quality. However, previous methods on aesthetic evaluation largely ignore the interpretability of the model…

Human-Computer Interaction · Computer Science 2022-02-10 Xiaoran Wu

Label-free imaging approaches seek to simplify and augment histopathologic assessment by replacing the current practice of staining by dyes to visualize tissue morphology with quantitative optical measurements. Quantitative phase imaging…

We present the Leuven Art Personalized Image Set (LAPIS), a novel dataset for personalized image aesthetic assessment (PIAA). It is the first dataset with images of artworks that is suitable for PIAA. LAPIS consists of 11,723 images and was…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Anne-Sofie Maerten , Li-Wei Chen , Stefanie De Winter , Christophe Bossens , Johan Wagemans

Several metrics exist to quantify the similarity between images, but they are inefficient when it comes to measure the similarity of highly distorted images. In this work, we propose to empirically investigate perceptual metrics based on…

Computer Vision and Pattern Recognition · Computer Science 2022-02-18 Rémi Kazmierczak , Gianni Franchi , Nacim Belkhir , Antoine Manzanera , David Filliat

Pathologists diagnose cancer using gigapixel whole-slide images (WSIs), but the current digital workflow is fragmented. These multiscale datasets often exceed 100,000 x 100,000 pixels, yet standard 2D monitors restrict the field of view.…

Human-Computer Interaction · Computer Science 2026-02-27 Jai Prakash Veerla , Partha Sai Guttikonda , Helen H. Shang , Mohammad Sadegh Nasr , Cesar Torres , Jacob M. Luber

This paper introduces a Virtual Immunohistochemistry Multiplex staining (VIMs) model designed to generate multiple immunohistochemistry (IHC) stains from a single hematoxylin and eosin (H&E) stained tissue section. IHC stains are crucial in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Shikha Dubey , Yosep Chong , Beatrice Knudsen , Shireen Y. Elhabian

Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Hengrong Lan , Jiali Gong , Fei Gao

Using a deep neural network, we demonstrate a digital staining technique, which we term PhaseStain, to transform quantitative phase images (QPI) of labelfree tissue sections into images that are equivalent to brightfield microscopy images…

Image and Video Processing · Electrical Eng. & Systems 2019-02-08 Yair Rivenson , Tairan Liu , Zhensong Wei , Yibo Zhang , Aydogan Ozcan

This study introduces a novel metric, the Index of Visual Similarity (IVS), to qualitatively characterize boiling heat transfer regimes using only visual data. The IVS is constructed by combining morphological similarity, through SIFT-based…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Pranay Nirapure , Ayushman Singh , Srikanth Rangarajan , Bahgat Sammakia

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Biometric has been increasing in relevance these days since it can be used for several applications such as access control for instance. Unfortunately, with the increased deployment of biometric applications, we observe an increase of…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Jose Maureira , Juan Tapia , Claudia Arellano , Christoph Busch

Histochemical staining is essential for visualizing tissue architecture and cellular morphology but is destructive and limited by the availability of tissue for multiple stains. Virtual staining with label-free microscopy offers a…

In the clinic, resected tissue samples are stained with Hematoxylin-and-Eosin (H&E) and/or Immunhistochemistry (IHC) stains and presented to the pathologists on glass slides or as digital scans for diagnosis and assessment of disease…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Parmida Ghahremani , Joseph Marino , Ricardo Dodds , Saad Nadeem

With the rapid development of digital pathology, virtual staining has become a key technology in multimedia medical information systems, offering new possibilities for the analysis and diagnosis of pathological images. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Hao Yang , JianYu Wu , Run Fang , Xuelian Zhao , Yuan Ji , Zhiyu Chen , Guibin He , Junceng Guo , Yang Liu , Xinhua Zeng

Tumor spatial heterogeneity analysis requires precise correlation between Hematoxylin and Eosin H&E morphology and immunohistochemical (IHC) biomarker expression, yet current methods suffer from spatial misalignment in consecutive sections,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yizhe Yuan , Bingsen Xue , Bangzheng Pu , Chengxiang Wang , Cheng Jin

Image quality assessment (IQA) is crucial in the evaluation stage of novel algorithms operating on images, including traditional and machine learning based methods. Due to the lack of available quality-rated medical images, most commonly…

Image and Video Processing · Electrical Eng. & Systems 2026-05-01 Anna Breger , Janek Gröhl , Clemens Karner , Thomas R Else , Ian Selby , Tom Rix , Lara-Sophie Witt , Merle Duchêne , Jonathan Weir-McCall , Carola-Bibiane Schönlieb

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

Digital pathology offers a groundbreaking opportunity to transform clinical practice in histopathological image analysis, yet faces a significant hurdle: the substantial file sizes of pathological Whole Slide Images (WSI). While current…

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

Medical Physics · Physics 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio